Thomas Höfer
Thomas Höfer
Division head, German Cancer Research Center & Professor, University of Heidelberg
Verified email at
Cited by
Cited by
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch, A Acs, D Adam, S Adam‐Klages, ...
European journal of immunology 49 (10), 1457-1973, 2019
Fundamental properties of unperturbed haematopoiesis from stem cells in vivo
K Busch, K Klapproth, M Barile, M Flossdorf, T Holland-Letz, ...
Nature 518 (7540), 542-546, 2015
Telomerase activation by genomic rearrangements in high-risk neuroblastoma
M Peifer, F Hertwig, F Roels, D Dreidax, M Gartlgruber, R Menon, ...
Nature 526 (7575), 700-704, 2015
Modelling of simple and complex calcium oscillations: From single‐cell responses to intercellular signalling
S Schuster, M Marhl, T Höfer
European Journal of Biochemistry 269 (5), 1333-1355, 2002
Disparate individual fates compose robust CD8+ T cell immunity
VR Buchholz, M Flossdorf, I Hensel, L Kretschmer, B Weissbrich, P Gräf, ...
Science 340 (6132), 630-635, 2013
Constitutively active Lck kinase in T cells drives antigen receptor signal transduction
K Nika, C Soldani, M Salek, W Paster, A Gray, R Etzensperger, L Fugger, ...
Immunity 32 (6), 766-777, 2010
Sequential polarization and imprinting of type 1 T helper lymphocytes by interferon-γ and interleukin-12
EG Schulz, L Mariani, A Radbruch, T Höfer
Immunity 30 (5), 673-683, 2009
The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes
AB Stittrich, C Haftmann, E Sgouroudis, AA Kühl, AN Hegazy, I Panse, ...
Nature immunology 11 (11), 1057-1062, 2010
Polylox barcoding reveals haematopoietic stem cell fates realized in vivo
W Pei, TB Feyerabend, J Rössler, X Wang, D Postrach, K Busch, I Rode, ...
Nature 548 (7668), 456-460, 2017
Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8+ central memory T cells
P Graef, VR Buchholz, C Stemberger, M Flossdorf, L Henkel, ...
Immunity 41 (1), 116-126, 2014
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments
D Busse, M de la Rosa, K Hobiger, K Thurley, M Flossdorf, A Scheffold, ...
Proceedings of the National Academy of Sciences 107 (7), 3058-3063, 2010
Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR
UM Litzenburger, CA Opitz, F Sahm, KJ Rauschenbach, S Trump, ...
Oncotarget 5 (4), 1038, 2014
Multisite protein phosphorylation–from molecular mechanisms to kinetic models
C Salazar, T Höfer
The FEBS journal 276 (12), 3177-3198, 2009
Control and plasticity of intercellular calcium waves in astrocytes: a modeling approach
T Höfer, L Venance, C Giaume
Journal of Neuroscience 22 (12), 4850-4859, 2002
Genome-wide nucleosome positioning during embryonic stem cell development
VB Teif, Y Vainshtein, M Caudron-Herger, JP Mallm, C Marth, T Höfer, ...
Nature structural & molecular biology 19 (11), 1185-1192, 2012
Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems
A Raue, B Steiert, M Schelker, C Kreutz, T Maiwald, H Hass, J Vanlier, ...
Bioinformatics 31 (21), 3558-3560, 2015
Regulation of CD4+CD25+ regulatory T cell activity: it takes (IL‐)two to tango
A Scheffold, J Hühn, T Höfer
European journal of immunology 35 (5), 1336-1341, 2005
Evolutionary trajectories of IDHWT glioblastomas reveal a common path of early tumorigenesis instigated years ahead of initial diagnosis
V Körber, J Yang, P Barah, Y Wu, D Stichel, Z Gu, MNC Fletcher, D Jones, ...
Cancer cell 35 (4), 692-704. e12, 2019
Single-cell RNA sequencing of tumor-infiltrating NK cells reveals that inhibition of transcription factor HIF-1α unleashes NK cell activity
J Ni, X Wang, A Stojanovic, Q Zhang, M Wincher, L Bühler, A Arnold, ...
Immunity 52 (6), 1075-1087. e8, 2020
A cholesterol-based allostery model of T cell receptor phosphorylation
M Swamy, K Beck-Garcia, E Beck-Garcia, FA Hartl, A Morath, OS Yousefi, ...
Immunity 44 (5), 1091-1101, 2016
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