Drug combination therapy increases successful drug repositioning W Sun, PE Sanderson, W Zheng Drug discovery today 21 (7), 1189–1195, 2016 | 368 | 2016 |
Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs J Kouznetsova, W Sun, C Martínez-Romero, G Tawa, P Shinn, CZ Chen, ... Emerging microbes & infections 3 (1), 1-7, 2014 | 261 | 2014 |
Drug repurposing screens and synergistic drug‐combinations for infectious diseases W Zheng, W Sun, A Simeonov British journal of pharmacology 175 (2), 181-191, 2018 | 219 | 2018 |
δ-Tocopherol reduces lipid accumulation in Niemann-Pick type C1 and Wolman cholesterol storage disorders M Xu, K Liu, M Swaroop, FD Porter, R Sidhu, S Finkes, DS Ory, ... Journal of Biological Chemistry 287 (47), 39349-39360, 2012 | 163 | 2012 |
Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry S Yang, M Xu, EM Lee, K Gorshkov, SA Shiryaev, S He, W Sun, ... Cell discovery 4 (1), 31, 2018 | 145 | 2018 |
Chemical signatures and new drug targets for gametocytocidal drug development W Sun, TQ Tanaka, CT Magle, W Huang, N Southall, R Huang, ... Scientific reports 4 (1), 3743, 2014 | 129 | 2014 |
A facile and highly efficient route to α-amino phosphonates via three-component reactions catalyzed by Mg (ClO 4) 2 or molecular iodine J Wu, W Sun, HG Xia, X Sun Organic & Biomolecular Chemistry 4 (9), 1663-1666, 2006 | 126 | 2006 |
Synergistic drug combination effectively blocks Ebola virus infection W Sun, S He, C Martínez-Romero, J Kouznetsova, G Tawa, M Xu, P Shinn, ... Antiviral Research 137, 165–172, 2016 | 102 | 2016 |
Drug discovery and development for rare genetic disorders W Sun, W Zheng, A Simeonov American Journal of Medical Genetics Part A, 2017 | 95 | 2017 |
Rapid antimicrobial susceptibility test for identification of new therapeutics and drug combinations against multidrug-resistant bacteria W Sun, RA Weingarten, M Xu, N Southall, S Dai, P Shinn, PE Sanderson, ... Emerging microbes & infections 5 (1), 1-11, 2016 | 89 | 2016 |
AgOTf-Catalyzed three-component reactions of 2-alkynylbenzaldehydes, amines, and diethylphosphite. An efficient route to 2, 3-disubstituted-1, 2-dihydroisoquinolin-1-ylphosphonates W Sun, Q Ding, X Sun, R Fan, J Wu Journal of Combinatorial Chemistry 9 (4), 690-694, 2007 | 89 | 2007 |
N-Heterocyclic carbene: a highly efficient catalyst in the reactions of aziridines with silylated nucleophiles J Wu, X Sun, S Ye, W Sun Tetrahedron letters 47 (28), 4813-4816, 2006 | 86 | 2006 |
A phenotypic compound screening assay for lysosomal storage diseases M Xu, K Liu, M Swaroop, W Sun, SJ Dehdashti, JC McKew, W Zheng Journal of Biomolecular Screening 19 (1), 168-175, 2014 | 80 | 2014 |
ADAM12 induces EMT and promotes cell migration, invasion and proliferation in pituitary adenomas via EGFR/ERK signaling pathway J Wang, Z Zhang, R Li, F Mao, W Sun, J Chen, H Zhang, JW Bartsch, ... Biomedicine & Pharmacotherapy 97, 1066-1077, 2018 | 72 | 2018 |
Expeditious approach to α-amino phosphonates via three-component solvent-free reactions catalyzed by NBS or CBr 4 J Wu, W Sun, X Sun, HG Xia Green Chemistry 8 (4), 365-367, 2006 | 67 | 2006 |
DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer Y Meng, CW Chen, MMH Yung, W Sun, J Sun, Z Li, J Li, Z Li, W Zhou, ... Cancer letters 428, 104-116, 2018 | 65 | 2018 |
Metarrestin, a perinucleolar compartment inhibitor, effectively suppresses metastasis KJ Frankowski, C Wang, S Patnaik, FJ Schoenen, N Southall, D Li, ... Science translational medicine 10 (441), eaap8307, 2018 | 65 | 2018 |
Gold (III) Chloride/Silver Triflate: A Highly Efficient Catalyst for Ring‐Opening Reaction of Aziridines with Electron‐Rich Arenes X Sun, W Sun, R Fan, J Wu Advanced Synthesis & Catalysis 349 (13), 2151-2155, 2007 | 65 | 2007 |
A highly efficient and general method for the ring-opening of aziridines with various nucleophiles in DMSO J Wu, X Sun, W Sun Organic & Biomolecular Chemistry 4 (22), 4231-4235, 2006 | 55 | 2006 |
Expeditious approach to coumarins via Pechmann reaction catalyzed by molecular iodine or AgOTf J Wu, T Diao, W Sun, Y Li Synthetic communications 36 (20), 2949-2956, 2006 | 41 | 2006 |