| Two CES1 gene mutations lead to dysfunctional carboxylesterase 1 activity in man: clinical significance and molecular basis HJ Zhu, KS Patrick, HJ Yuan, JS Wang, JL Donovan, CL DeVane, ... The American Journal of Human Genetics 82 (6), 1241-1248, 2008 | 256 | 2008 |
| Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana HJ Zhu, JS Wang, JS Markowitz, JL Donovan, BB Gibson, HA Gefroh, ... Journal of Pharmacology and Experimental Therapeutics 317 (2), 850-857, 2006 | 207 | 2006 |
| Carboxylesterase 1 as a determinant of clopidogrel metabolism and activation HJ Zhu, X Wang, BE Gawronski, BJ Brinda, DJ Angiolillo, JS Markowitz Journal of Pharmacology and Experimental Therapeutics 344 (3), 665-672, 2013 | 199 | 2013 |
| Berberine promotes glucagon-like peptide-1 (7–36) amide secretion in streptozotocin-induced diabetic rats SS Lu, YL Yu, HJ Zhu, XD Liu, L Liu, YW Liu, P Wang, L Xie, GJ Wang Journal of Endocrinology 200 (2), 159-165, 2009 | 152 | 2009 |
| Evaluation of antipsychotic drugs as inhibitors of multidrug resistance transporter P-glycoprotein JS Wang, HJ Zhu, JS Markowitz, JL Donovan, CL DeVane Psychopharmacology 187 (4), 415-423, 2006 | 148 | 2006 |
| Glutamate up-regulates P-glycoprotein expression in rat brain microvessel endothelial cells by an NMDA receptor-mediated mechanism HJ Zhu, GQ Liu Life sciences 75 (11), 1313-1322, 2004 | 146 | 2004 |
| Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender J Shi, X Wang, JH Nguyen, BE Bleske, Y Liang, L Liu, HJ Zhu Biochemical Pharmacology 119, 76-84, 2016 | 107 | 2016 |
| An assessment of pharmacokinetics and antioxidant activity of free silymarin flavonolignans in healthy volunteers: A dose escalation study HJ Zhu, BJ Brinda, KD Chavin, HJ Bernstein, KS Patrick, JS Markowitz Drug Metabolism and Disposition 41 (9), 1679-1685, 2013 | 104 | 2013 |
| Age-and sex-related expression and activity of carboxylesterase 1 and 2 in mouse and human liver HJ Zhu, DI Appel, Y Jiang, JS Markowitz Drug Metabolism and Disposition 37 (9), 1819-1825, 2009 | 101 | 2009 |
| Activation of the antiviral prodrug oseltamivir is impaired by two newly identified carboxylesterase 1 variants HJ Zhu, JS Markowitz Drug Metabolism and Disposition 37 (2), 264-267, 2009 | 101 | 2009 |
| Risperidone and paliperidone inhibit p-glycoprotein activity in vitro HJ Zhu, JS Wang, JS Markowitz, JL Donovan, BB Gibson, CL DeVane Neuropsychopharmacology 32 (4), 757-764, 2007 | 98 | 2007 |
| The effects of Milk Thistle (Silybum marianum) on human cytochrome P450 activity M Kawaguchi-Suzuki, RF Frye, HJ Zhu, BJ Brinda, KD Chavin, ... Drug Metabolism and Disposition 42 (10), 1611-1616, 2014 | 89 | 2014 |
| Sertraline and its metabolite desmethylsertraline, but not bupropion or its three major metabolites, have high affinity for P-glycoprotein JS Wang, HJ Zhu, BB Gibson, JS Markowitz, JL Donovan, CL DeVane Biological & pharmaceutical bulletin 31 (2), 231, 2008 | 89 | 2008 |
| Long-term consequences of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic factor heterozygous mice HA Boger, LD Middaugh, KS Patrick, S Ramamoorthy, ED Denehy, H Zhu, ... The Journal of Neuroscience 27 (33), 8816-8825, 2007 | 86 | 2007 |
| Pharmacokinetics of Olanzapine After Single‐Dose Oral Administration of Standard Tablet Versus Normal and Sublingual Administration of an Orally Disintegrating Tablet in Normal … JS Markowitz, CL DeVane, RJ Malcolm, HA Gefroh, JS Wang, HJ Zhu, ... The Journal of Clinical Pharmacology 46 (2), 164-171, 2006 | 81 | 2006 |
| Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril HJ Zhu, DI Appel, JA Johnson, KD Chavin, JS Markowitz Biochemical pharmacology 77 (7), 1266-1272, 2009 | 77 | 2009 |
| Carboxylesterase 1 and Precision Pharmacotherapy: Pharmacogenetics and Nongenetic Regulators L Her, HJ Zhu Drug Metabolism and Disposition 48 (3), 230-244, 2020 | 73 | 2020 |
| Label-free absolute protein quantification with data-independent acquisition B He, J Shi, X Wang, H Jiang, HJ Zhu Journal of proteomics 200, 51-59, 2019 | 71 | 2019 |
| Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation J Shi, X Wang, J Nguyen, AH Wu, BE Bleske, HJ Zhu Drug Metab Dispos, 2016 | 71 | 2016 |
| Antipsychotic drugs inhibit the function of breast cancer resistance protein JS Wang, HJ Zhu, JS Markowitz, JL Donovan, HJ Yuan, CL DeVane Basic & clinical pharmacology & toxicology 103 (4), 336-341, 2008 | 71 | 2008 |
