Michael Clerx
Michael Clerx
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Myokit: A simple interface to cardiac cellular electrophysiology
M Clerx, P Collins, E de Lange, PGA Volders
Progress in Biophysics and Molecular Biology 120 (1-3), 100-114, 2016
Calibration of ionic and cellular cardiac electrophysiology models
DG Whittaker, M Clerx, CL Lei, DJ Christini, GR Mirams
Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2020
Probabilistic Inference on Noisy Time Series (PINTS)
M Clerx, M Robinson, B Lambert, CL Lei, S Ghosh, GR Mirams, ...
Journal of Open Research Software 7 (1), 23, 2019
Four ways to fit an ion channel model
M Clerx, KA Beattie, DJ Gavaghan, GR Mirams
Biophysical journal 117 (12), 2420-2437, 2019
Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology
CL Lei, K Wang, M Clerx, RH Johnstone, MP Hortigon-Vinagre, V Zamora, ...
Frontiers in Physiology 8, 986, 2017
Rapid characterization of hERG channel kinetics I: using an automated high-throughput system
CL Lei, M Clerx, DJ Gavaghan, L Polonchuk, GR Mirams, K Wang
Biophysical journal 117 (12), 2438-2454, 2019
Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments
CL Lei, M Clerx, DG Whittaker, DJ Gavaghan, TP De Boer, GR Mirams
Philosophical Transactions of the Royal Society A 378 (2173), 20190348, 2020
Rapid characterization of hERG channel kinetics II: temperature dependence
CL Lei, M Clerx, KA Beattie, D Melgari, JC Hancox, DJ Gavaghan, ...
Biophysical journal 117 (12), 2455-2470, 2019
Predicting changes to INa from missense mutations in human SCN5A
M Clerx, J Heijman, P Collins, PGA Volders
Scientific Reports 8 (1), 12797, 2018
CellML 2.0
M Clerx, MT Cooling, J Cooper, A Garny, K Moyle, DP Nickerson, ...
Journal of Integrative Bioinformatics 17 (2-3), 2020
Maastricht antiarrhythmic drug evaluator (MANTA): A computational tool for better understanding of antiarrhythmic drugs
H Sutanto, L Laudy, M Clerx, D Dobrev, HJGM Crijns, J Heijman
Pharmacological research 148, 104444, 2019
Reproducible model development in the Cardiac Electrophysiology Web Lab
AC Daly, M Clerx, KA Beattie, J Cooper, DJ Gavaghan, GR Mirams
Progress in Biophysics and Molecular Biology, 2018
Physiology-based regularization of the electrocardiographic inverse problem
MJM Cluitmans, M Clerx, N Vandersickel, RLM Peeters, PGA Volders, ...
Medical & biological engineering & computing, 1-13, 2016
Applying novel identification protocols to Markov models of INa
M Clerx, P Collins, PGA Volders
Computing in Cardiology 2015, 2015
A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer
CL Lei, A Fabbri, DG Whittaker, M Clerx, MJ Windley, AP Hill, GR Mirams, ...
Wellcome Open Research 5, 152, 2021
Autocorrelated measurement processes and inference for ordinary differential equation models of biological systems
B Lambert, CL Lei, M Robinson, M Clerx, R Creswell, S Ghosh, S Tavener, ...
Journal of the Royal Society Interface 20 (199), 20220725, 2023
Personalisation of cellular electrophysiology models: utopia?
M Clerx
Computing in Cardiology 45, 2018
Immediate and delayed response of simulated human atrial myocytes to clinically-relevant hypokalemia
M Clerx, GR Mirams, AJ Rogers, SM Narayan, WR Giles
Frontiers in physiology 12, 651162, 2021
Myokit: A Framework for Computational Cellular Electrophysiology
M Clerx, PGA Volders, P Collins
Computing in Cardiology 41, 229-232, 2014
Models of the cardiac L‐type calcium current: A quantitative review
A Agrawal, K Wang, L Polonchuk, J Cooper, M Hendrix, DJ Gavaghan, ...
WIREs Mechanisms of Disease, e1581, 2022
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