Michael Clerx

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Gary MiramsCentre for Mathematical Medicine & Biology, University of NottinghamVerified email at nottingham.ac.uk
David GavaghanProfessor of Computational Biology, University of OxfordVerified email at cs.ox.ac.uk
Chon Lok LeiUniversity of MacauVerified email at um.edu.mo
Paul VoldersHoogleraar Genetische Cardiologie, Universiteit MaastrichtVerified email at maastrichtuniversity.nl
Dominic G WhittakerGSKVerified email at gsk.com
Pieter CollinsDepartment of Data Science and Knowledge Engineering, Maastricht UniversityVerified email at maastrichtuniversity.nl
Jonathan CooperUniversity College LondonVerified email at ucl.ac.uk
Teun P. de BoerAssociate Professor, Department of Medical Physiology, University Medical Center UtrechtVerified email at umcutrecht.nl
Kylie A BeattieGlaxoSmithKlineVerified email at gsk.com
Martin RobinsonHead of Research Software Engineering, Department of Computer Science, University of OxfordVerified email at cs.ox.ac.uk
Ben LambertUniversity of OxfordVerified email at stats.ox.ac.uk
David ChristiniProfessor, Weill Cornell Medical CollegeVerified email at med.cornell.edu
Ross H. JohnstoneDPhil, University of OxfordVerified email at pm.me
sanmitra ghoshMRC Postdoctoral Fellow, MRC Biostatistics Unit, University of CambridgeVerified email at mrc-bsu.cam.ac.uk
Jordi HeijmanDiv of Medical Physics & Biophysics, Gottfried Schatz Research Center, Medical University of GrazVerified email at medunigraz.at
Poul NielsenProfessor, Engineering Science and Auckland Bioengineering Institute, University of AucklandVerified email at auckland.ac.nz
Alan GarnyAuckland Bioengineering Institute, University of AucklandVerified email at auckland.ac.nz
David Phillip NickersonAuckland Bioengineering Institute, University of AucklandVerified email at auckland.ac.nz
Matthijs CluitmansMaastricht University & Philips ResearchVerified email at maastrichtuniversity.nl
Ralf PeetersProfessor in Mathematics, Dept. Advanced Computing Sciences, Maastricht UniversityVerified email at maastrichtuniversity.nl

Michael Clerx

Researcher, University of Nottingham

Verified email at nottingham.ac.uk - Homepage

Cardiac cellular electrophysiology & modelling


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Myokit: A simple interface to cardiac cellular electrophysiology M Clerx, P Collins, E de Lange, PGA Volders Progress in Biophysics and Molecular Biology 120 (1-3), 100-114, 2016	119	2016
Calibration of ionic and cellular cardiac electrophysiology models DG Whittaker, M Clerx, CL Lei, DJ Christini, GR Mirams Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2020	99	2020
Probabilistic Inference on Noisy Time Series (PINTS) M Clerx, M Robinson, B Lambert, CL Lei, S Ghosh, GR Mirams, ... Journal of Open Research Software 7 (1), 23, 2019	60	2019
Four ways to fit an ion channel model M Clerx, KA Beattie, DJ Gavaghan, GR Mirams Biophysical journal 117 (12), 2420-2437, 2019	57	2019
Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments CL Lei, M Clerx, DG Whittaker, DJ Gavaghan, TP De Boer, GR Mirams Philosophical Transactions of the Royal Society A 378 (2173), 20190348, 2020	56	2020
Rapid characterization of hERG channel kinetics I: using an automated high-throughput system CL Lei, M Clerx, DJ Gavaghan, L Polonchuk, GR Mirams, K Wang Biophysical journal 117 (12), 2438-2454, 2019	54	2019
Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology CL Lei, K Wang, M Clerx, RH Johnstone, MP Hortigon-Vinagre, V Zamora, ... Frontiers in Physiology 8, 986, 2017	50	2017
Rapid characterization of hERG channel kinetics II: temperature dependence CL Lei, M Clerx, KA Beattie, D Melgari, JC Hancox, DJ Gavaghan, ... Biophysical journal 117 (12), 2455-2470, 2019	48	2019
Predicting changes to INa from missense mutations in human SCN5A M Clerx, J Heijman, P Collins, PGA Volders Scientific Reports 8 (1), 12797, 2018	33	2018
Maastricht antiarrhythmic drug evaluator (MANTA): A computational tool for better understanding of antiarrhythmic drugs H Sutanto, L Laudy, M Clerx, D Dobrev, HJGM Crijns, J Heijman Pharmacological research 148, 104444, 2019	32	2019
CellML 2.0 M Clerx, MT Cooling, J Cooper, A Garny, K Moyle, DP Nickerson, ... Journal of Integrative Bioinformatics 17 (2-3), 2020	31	2020
Reproducible model development in the Cardiac Electrophysiology Web Lab AC Daly, M Clerx, KA Beattie, J Cooper, DJ Gavaghan, GR Mirams Progress in Biophysics and Molecular Biology, 2018	26	2018
Physiology-based regularization of the electrocardiographic inverse problem MJM Cluitmans, M Clerx, N Vandersickel, RLM Peeters, PGA Volders, ... Medical & biological engineering & computing, 1-13, 2016	25	2016
A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer CL Lei, A Fabbri, DG Whittaker, M Clerx, MJ Windley, AP Hill, GR Mirams, ... Wellcome Open Research 5, 152, 2021	15	2021
Autocorrelated measurement processes and inference for ordinary differential equation models of biological systems B Lambert, CL Lei, M Robinson, M Clerx, R Creswell, S Ghosh, S Tavener, ... Journal of the Royal Society Interface 20 (199), 20220725, 2023	13	2023
Models of the cardiac L‐type calcium current: A quantitative review A Agrawal, K Wang, L Polonchuk, J Cooper, M Hendrix, DJ Gavaghan, ... WIREs Mechanisms of Disease, e1581, 2022	11*	2022
Applying novel identification protocols to Markov models of INa M Clerx, P Collins, PGA Volders Computing in Cardiology 2015, 2015	11	2015
Model-driven optimal experimental design for calibrating cardiac electrophysiology models CL Lei, M Clerx, DJ Gavaghan, GR Mirams Computer Methods and Programs in Biomedicine 240, 107690, 2023	9	2023
Leak current, even with gigaohm seals, can cause misinterpretation of stem cell-derived cardiomyocyte action potential recordings AP Clark, M Clerx, S Wei, CL Lei, TP de Boer, GR Mirams, DJ Christini, ... Europace 25 (9), euad243, 2023	7	2023
Personalisation of cellular electrophysiology models: utopia? M Clerx Computing in Cardiology 45, 2018	7	2018

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