Michael Clerx

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Gary MiramsCentre for Mathematical Medicine & Biology, University of NottinghamVerified email at nottingham.ac.uk
David GavaghanProfessor of Computational Biology, University of OxfordVerified email at cs.ox.ac.uk
Chon Lok LeiUniversity of MacauVerified email at um.edu.mo
Paul VoldersHoogleraar Genetische Cardiologie, Universiteit MaastrichtVerified email at maastrichtuniversity.nl
Pieter CollinsDepartment of Data Science and Knowledge Engineering, Maastricht UniversityVerified email at maastrichtuniversity.nl
Dominic G WhittakerGSKVerified email at gsk.com
Jonathan CooperUniversity College LondonVerified email at ucl.ac.uk
Kylie A BeattieGlaxoSmithKlineVerified email at gsk.com
Martin RobinsonHead of Research Software Engineering, Department of Computer Science, University of OxfordVerified email at cs.ox.ac.uk
Ben LambertUniversity of OxfordVerified email at stats.ox.ac.uk
Teun P. de BoerAssociate Professor, Department of Medical Physiology, University Medical Center UtrechtVerified email at umcutrecht.nl
David ChristiniProfessor, Weill Cornell Medical CollegeVerified email at med.cornell.edu
Ross H. JohnstoneDPhil, University of OxfordVerified email at pm.me
Jordi HeijmanDepartment of Cardiology, Maastricht University Medical CentreVerified email at maastrichtuniversity.nl
sanmitra ghoshMRC Postdoctoral Fellow, MRC Biostatistics Unit, University of CambridgeVerified email at mrc-bsu.cam.ac.uk
Poul NielsenProfessor, Engineering Science and Auckland Bioengineering Institute, University of AucklandVerified email at auckland.ac.nz
Alan GarnyAuckland Bioengineering Institute, University of AucklandVerified email at auckland.ac.nz
David Phillip NickersonAuckland Bioengineering Institute, University of AucklandVerified email at auckland.ac.nz
Matthijs CluitmansMaastricht University & Philips ResearchVerified email at maastrichtuniversity.nl
Ralf PeetersProfessor in Mathematics, Dept. Advanced Computing Sciences, Maastricht UniversityVerified email at maastrichtuniversity.nl

Michael Clerx

Researcher, University of Nottingham

Verified email at nottingham.ac.uk - Homepage

Cardiac cellular electrophysiology & modelling


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Myokit: A simple interface to cardiac cellular electrophysiology M Clerx, P Collins, E de Lange, PGA Volders Progress in Biophysics and Molecular Biology 120 (1-3), 100-114, 2016	103	2016
Calibration of ionic and cellular cardiac electrophysiology models DG Whittaker, M Clerx, CL Lei, DJ Christini, GR Mirams Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2020	85	2020
Probabilistic Inference on Noisy Time Series (PINTS) M Clerx, M Robinson, B Lambert, CL Lei, S Ghosh, GR Mirams, ... Journal of Open Research Software 7 (1), 23, 2019	46	2019
Four ways to fit an ion channel model M Clerx, KA Beattie, DJ Gavaghan, GR Mirams Biophysical journal 117 (12), 2420-2437, 2019	44	2019
Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology CL Lei, K Wang, M Clerx, RH Johnstone, MP Hortigon-Vinagre, V Zamora, ... Frontiers in Physiology 8, 986, 2017	44	2017
Rapid characterization of hERG channel kinetics I: using an automated high-throughput system CL Lei, M Clerx, DJ Gavaghan, L Polonchuk, GR Mirams, K Wang Biophysical journal 117 (12), 2438-2454, 2019	41	2019
Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage-clamp experiments CL Lei, M Clerx, DG Whittaker, DJ Gavaghan, TP De Boer, GR Mirams Philosophical Transactions of the Royal Society A 378 (2173), 20190348, 2020	40	2020
Rapid characterization of hERG channel kinetics II: temperature dependence CL Lei, M Clerx, KA Beattie, D Melgari, JC Hancox, DJ Gavaghan, ... Biophysical journal 117 (12), 2455-2470, 2019	34	2019
Predicting changes to INa from missense mutations in human SCN5A M Clerx, J Heijman, P Collins, PGA Volders Scientific Reports 8 (1), 12797, 2018	29	2018
CellML 2.0 M Clerx, MT Cooling, J Cooper, A Garny, K Moyle, DP Nickerson, ... Journal of Integrative Bioinformatics 17 (2-3), 2020	28	2020
Maastricht antiarrhythmic drug evaluator (MANTA): A computational tool for better understanding of antiarrhythmic drugs H Sutanto, L Laudy, M Clerx, D Dobrev, HJGM Crijns, J Heijman Pharmacological research 148, 104444, 2019	28	2019
Reproducible model development in the Cardiac Electrophysiology Web Lab AC Daly, M Clerx, KA Beattie, J Cooper, DJ Gavaghan, GR Mirams Progress in Biophysics and Molecular Biology, 2018	25	2018
Physiology-based regularization of the electrocardiographic inverse problem MJM Cluitmans, M Clerx, N Vandersickel, RLM Peeters, PGA Volders, ... Medical & biological engineering & computing, 1-13, 2016	21	2016
Applying novel identification protocols to Markov models of INa M Clerx, P Collins, PGA Volders Computing in Cardiology 2015, 2015	11	2015
A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer CL Lei, A Fabbri, DG Whittaker, M Clerx, MJ Windley, AP Hill, GR Mirams, ... Wellcome Open Research 5, 152, 2021	8	2021
Autocorrelated measurement processes and inference for ordinary differential equation models of biological systems B Lambert, CL Lei, M Robinson, M Clerx, R Creswell, S Ghosh, S Tavener, ... Journal of the Royal Society Interface 20 (199), 20220725, 2023	6	2023
Personalisation of cellular electrophysiology models: utopia? M Clerx Computing in Cardiology 45, 2018	6	2018
Immediate and delayed response of simulated human atrial myocytes to clinically-relevant hypokalemia M Clerx, GR Mirams, AJ Rogers, SM Narayan, WR Giles Frontiers in physiology 12, 651162, 2021	5	2021
Myokit: A Framework for Computational Cellular Electrophysiology M Clerx, PGA Volders, P Collins Computing in Cardiology 41, 229-232, 2014	5	2014
Models of the cardiac L‐type calcium current: A quantitative review A Agrawal, K Wang, L Polonchuk, J Cooper, M Hendrix, DJ Gavaghan, ... WIREs Mechanisms of Disease, e1581, 2022	4*	2022

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