Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritis—structure, chaos and senescence T Aigner, S Söder, PM Gebhard, A McAlinden, J Haag Nature Clinical Practice Rheumatology 3 (7), 391-399, 2007 | 357 | 2007 |
Inflammation and epigenetic regulation in osteoarthritis J Shen, Y Abu-Amer, RJ O’keefe, A McAlinden Connective tissue research 58 (1), 49-63, 2017 | 236 | 2017 |
Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice SL Bonar, SD Brydges, JL Mueller, MD McGeough, C Pena, D Chen, ... PloS one 7 (4), e35979, 2012 | 116 | 2012 |
α-Helical coiled-coil oligomerization domains are almost ubiquitous in the collagen superfamily A McAlinden, TA Smith, LJ Sandell, D Ficheux, DAD Parry, DJS Hulmes Journal of Biological Chemistry 278 (43), 42200-42207, 2003 | 111 | 2003 |
Emerging roles for long noncoding RNAs in skeletal biology and disease NPT Huynh, BA Anderson, F Guilak, A McAlinden Connective tissue research 58 (1), 116-141, 2017 | 102 | 2017 |
Persistent depletion of I kappa B alpha and interleukin-8 expression in human pulmonary epithelial cells exposed to quartz particles RPF Schins, A McAlinden, W MacNee, LA Jimenez, JA Ross, K Guy, ... Toxicology and applied pharmacology 167 (2), 107-117, 2000 | 74 | 2000 |
Changes of chondrocyte expression profiles in human MSC aggregates in the presence of PEG microspheres and TGF-β3 S Ravindran, JL Roam, PK Nguyen, TM Hering, DL Elbert, A McAlinden Biomaterials 32 (33), 8436-8445, 2011 | 65 | 2011 |
Missense and nonsense mutations in the alternatively‐spliced exon 2 of COL2A1 cause the ocular variant of Stickler syndrome A McAlinden, M Majava, PN Bishop, R Perveen, GCM Black, ME Pierpont, ... Human mutation 29 (1), 83-90, 2008 | 64 | 2008 |
Processing of type II procollagen amino propeptide by matrix metalloproteinases N Fukui, A McAlinden, Y Zhu, E Crouch, TJ Broekelmann, RP Mecham, ... Journal of Biological Chemistry 277 (3), 2193-2201, 2002 | 63 | 2002 |
The amino-terminal heptad repeats of the coiled-coil neck domain of pulmonary surfactant protein D are necessary for the assembly of trimeric subunits and dodecamers P Zhang, A McAlinden, S Li, T Schumacher, H Wang, S Hu, L Sandell, ... Journal of Biological Chemistry 276 (23), 19862-19870, 2001 | 62 | 2001 |
MicroRNA-181a/b-1 over-expression enhances osteogenesis by modulating PTEN/PI3K/AKT signaling and mitochondrial metabolism H Zheng, J Liu, E Tycksen, R Nunley, A McAlinden Bone 123, 92-102, 2019 | 61 | 2019 |
DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism J Shen, C Wang, D Li, T Xu, J Myers, JM Ashton, T Wang, MJ Zuscik, ... JCI insight 2 (12), 2017 | 61 | 2017 |
Differentially expressed microRNAs in chondrocytes from distinct regions of developing human cartilage A McAlinden, N Varghese, L Wirthlin, LW Chang PloS one 8 (9), e75012, 2013 | 61 | 2013 |
Type IIA procollagen in development of the human intervertebral disc: Regulated expression of the NH2‐propeptide by enzymic processing reveals a unique … Y Zhu, A Mcalinden, LJ Sandell Developmental dynamics: an official publication of the American Association …, 2001 | 61 | 2001 |
The role of microRNAs in bone development AP Hensley, A McAlinden Bone 143, 115760, 2021 | 60 | 2021 |
Age-related changes in the synthesis and mRNA expression of decorin and aggrecan in human meniscus and articular cartilage A McAlinden, J Dudhia, MC Bolton, P Lorenzo, D Heinegård, MT Bayliss Osteoarthritis and Cartilage 9 (1), 33-41, 2001 | 60 | 2001 |
Alternative splicing of type II procollagen exon 2 is regulated by the combination of a weak 5′ splice site and an adjacent intronic stem-loop cis element A McAlinden, N Havlioglu, L Liang, SR Davies, LJ Sandell Journal of Biological Chemistry 280 (38), 32700-32711, 2005 | 58 | 2005 |
Nuclear protein TIA-1 regulates COL2A1 alternative splicing and interacts with precursor mRNA and genomic DNA A McAlinden, L Liang, Y Mukudai, T Imamura, LJ Sandell Journal of Biological Chemistry 282 (33), 24444-24454, 2007 | 55 | 2007 |
Upregulation of Runx2 and Osterix during in vitro chondrogenesis of human adipose-derived stromal cells JT Rich, I Rosová, JA Nolta, TM Myckatyn, LJ Sandell, A McAlinden Biochemical and biophysical research communications 372 (1), 230-235, 2008 | 46 | 2008 |
Expression of two novel alternatively spliced COL2A1 isoforms during chondrocyte differentiation A McAlinden, B Johnstone, J Kollar, N Kazmi, TM Hering Matrix Biology 27 (3), 254-266, 2008 | 39 | 2008 |