Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm I Aksoy, R Jauch, J Chen, M Dyla, U Divakar, GK Bogu, R Teo, ... The EMBO journal 32 (7), 938-953, 2013 | 213 | 2013 |
A unique Oct4 interface is crucial for reprogramming to pluripotency D Esch, J Vahokoski, MR Groves, V Pogenberg, V Cojocaru, ... Nature cell biology 15 (3), 295-301, 2013 | 162 | 2013 |
Conversion of Sox17 into a pluripotency reprogramming factor by reengineering its association with Oct4 on DNA R Jauch, I Aksoy, AP Hutchins, CKL Ng, XF Tian, J Chen, P Palasingam, ... Stem cells 29 (6), 940-951, 2011 | 113 | 2011 |
Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog R Jauch, CKL Ng, KS Saikatendu, RC Stevens, PR Kolatkar Journal of molecular biology 376 (3), 758-770, 2008 | 109 | 2008 |
Deciphering the Sox-Oct partner code by quantitative cooperativity measurements CKL Ng, NX Li, S Chee, S Prabhakar, PR Kolatkar, R Jauch Nucleic acids research 40 (11), 4933-4941, 2012 | 101 | 2012 |
The structure of Sox17 bound to DNA reveals a conserved bending topology but selective protein interaction platforms P Palasingam, R Jauch, CKL Ng, PR Kolatkar Journal of molecular biology 388 (3), 619-630, 2009 | 100 | 2009 |
The crystal structure of the Sox4 HMG domain–DNA complex suggests a mechanism for positional interdependence in DNA recognition R Jauch, CKL Ng, K Narasimhan, PR Kolatkar Biochemical Journal 443 (1), 39-47, 2012 | 87 | 2012 |
Sox transcription factors require selective interactions with Oct4 and specific transactivation functions to mediate reprogramming I Aksoy, R Jauch, V Eras, WA Chng, J Chen, U Divakar, CKL Ng, ... Stem cells 31 (12), 2632-2646, 2013 | 75 | 2013 |
Structural basis for the SOX-dependent genomic redistribution of OCT4 in stem cell differentiation F Merino, CKL Ng, V Veerapandian, HR Schöler, R Jauch, V Cojocaru Structure 22 (9), 1274-1286, 2014 | 54 | 2014 |
Evolution of the vertebrate gene regulatory network controlled by the transcriptional repressor REST R Johnson, J Samuel, CKL Ng, R Jauch, LW Stanton, IC Wood Molecular biology and evolution 26 (7), 1491-1507, 2009 | 48 | 2009 |
Changing POU dimerization preferences converts Oct6 into a pluripotency inducer S Jerabek, CKL Ng, G Wu, MJ Arauzo‐Bravo, KP Kim, D Esch, V Malik, ... EMBO reports 18 (2), 319-333, 2017 | 46 | 2017 |
Loss of the scavenger mRNA decapping enzyme DCPS causes syndromic intellectual disability with neuromuscular defects CKL Ng, M Shboul, V Taverniti, C Bonnard, H Lee, A Eskin, SF Nelson, ... Human Molecular Genetics 24 (11), 3163-3171, 2015 | 39 | 2015 |
Co-motif discovery identifies an Esrrb-Sox2-DNA ternary complex as a mediator of transcriptional differences between mouse embryonic and epiblast stem cells AP Hutchins, SH Choo, TK Mistri, M Rahmani, CT Woon, ... Stem Cells 31 (2), 269-281, 2013 | 38 | 2013 |
Sensitive plasma etching endpoint detection using tunable diode laser absorption spectroscopy HC Sun, V Patel, B Singh, CK Ng, EA Whittaker Applied physics letters 64 (21), 2779-2781, 1994 | 26 | 1994 |
Crystal structure of the dimeric Oct6 (POU3f1) POU domain bound to palindromic MORE DNA R Jauch, SH Choo, CK Ng, PR Kolatkar Proteins 79 (2), 674-677, 2011 | 25 | 2011 |
Combined wavelength and frequency modulation spectroscopy: a novel diagnostic tool for materials processing HC Sun, EA Whittaker, YW Bae, CK Ng, V Patel, WH Tam, S McGuire, ... Applied optics 32 (6), 885-893, 1993 | 24 | 1993 |
TherMos: Estimating protein–DNA binding energies from in vivo binding profiles W Sun, X Hu, MHK Lim, CKL Ng, SH Choo, DS Castro, D Drechsel, ... Nucleic acids research 41 (11), 5555-5568, 2013 | 23 | 2013 |
Purification, crystallization and preliminary X-ray diffraction analysis of the HMG domain of Sox17 in complex with DNA CKL Ng, P Palasingam, R Venkatachalam, N Baburajendran, J Cheng, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2008 | 15 | 2008 |
A fluid model for electron dynamics in the vacuum gap of a plasma opening switch CK Ng, RN Sudan Journal of applied physics 69 (1), 137-145, 1991 | 9 | 1991 |
Crystal optimization and preliminary diffraction data analysis of the Smad1 MH1 domain bound to a palindromic SBE DNA element N Baburajendran, P Palasingam, CKL Ng, R Jauch, PR Kolatkar Acta Crystallographica Section F: Structural Biology and Crystallization …, 2009 | 5 | 2009 |