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John F Gilmer
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Prodrugs for amines
AL Simplício, JM Clancy, JF Gilmer
Molecules 13 (3), 519-547, 2008
2152008
Matrix metalloproteinases in inflammatory bowel disease: an update
S O’Sullivan, JF Gilmer, C Medina
Mediators of inflammation 2015, 2015
2022015
Inhibition of acetylcholinesterase by tea tree oil
C Mills, BV Cleary, JJ Walsh, JF Gilmer
Journal of Pharmacy and Pharmacology 56 (3), 375-379, 2004
1932004
Nitric oxide-matrix metaloproteinase-9 interactions: biological and pharmacological significance: NO and MMP-9 interactions
S O'Sullivan, C Medina, M Ledwidge, MW Radomski, JF Gilmer
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (3), 603-617, 2014
1192014
A steroid‐based cryptand for halide anions
AP Davis, JF Gilmer, JJ Perry
Angewandte Chemie International Edition in English 35 (12), 1312-1315, 1996
1161996
Mechanisms of platelet-stimulated colon cancer invasion: role of clusterin and thrombospondin 1 in regulation of the P38MAPK–MMP-9 pathway
A Radziwon-Balicka, MJ Santos-Martinez, JJ Corbalan, S O’Sullivan, ...
Carcinogenesis 35 (2), 324-332, 2014
1022014
Bile acid toxicity structure–activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line …
R Sharma, F Majer, VK Peta, J Wang, R Keaveney, D Kelleher, A Long, ...
Bioorganic & medicinal chemistry 18 (18), 6886-6895, 2010
782010
Advances in bile acid medicinal chemistry
R Sharma, A Long, JF Gilmer
Current medicinal chemistry 18 (26), 4029-4052, 2011
732011
Isosorbide-2-benzyl carbamate-5-salicylate, a peripheral anionic site binding subnanomolar selective butyrylcholinesterase inhibitor
CG Carolan, GP Dillon, D Khan, SA Ryder, JM Gaynor, S Reidy, ...
Journal of medicinal chemistry 53 (3), 1190-1199, 2010
712010
β-Aminoketones as prodrugs with pH-controlled activation
AL Simplício, JM Clancy, JF Gilmer
International journal of pharmaceutics 336 (2), 208-214, 2007
542007
N-Substituted homopiperazine barbiturates as gelatinase inhibitors
J Wang, C Medina, MW Radomski, JF Gilmer
Bioorganic & medicinal chemistry 19 (16), 4985-4999, 2011
502011
Ursodeoxycholic acid amides as novel glucocorticoid receptor modulators
R Sharma, D Prichard, F Majer, AM Byrne, D Kelleher, A Long, JF Gilmer
Journal of medicinal chemistry 54 (1), 122-130, 2011
492011
Discovery of a “true” aspirin prodrug
LM Moriarty, MN Lally, CG Carolan, M Jones, JM Clancy, JF Gilmer
Journal of medicinal chemistry 51 (24), 7991-7999, 2008
452008
The aqueous stability of bupropion
PM O’Byrne, R Williams, JJ Walsh, JF Gilmer
Journal of pharmaceutical and biomedical analysis 53 (3), 376-381, 2010
412010
Isosorbide-based aspirin prodrugs: II. Hydrolysis kinetics of isosorbide diaspirinate
JF Gilmer, LM Moriarty, MN Lally, JM Clancy
European journal of pharmaceutical sciences 16 (4-5), 297-304, 2002
412002
Ursodeoxycholic acid attenuates colonic epithelial secretory function
OB Kelly, MS Mroz, JBJ Ward, C Colliva, M Scharl, R Pellicciari, JF Gilmer, ...
The Journal of physiology 591 (9), 2307-2318, 2013
402013
Isosorbide-based aspirin prodrugs: integration of nitric oxide releasing groups
M Jones, I Inkielewicz, C Medina, MJ Santos-Martinez, A Radomski, ...
Journal of medicinal chemistry 52 (21), 6588-6598, 2009
402009
Isosorbide-2-carbamate esters: potent and selective butyrylcholinesterase inhibitors
CG Carolan, GP Dillon, JM Gaynor, S Reidy, SA Ryder, D Khan, ...
Journal of medicinal chemistry 51 (20), 6400-6409, 2008
402008
New highly toxic bile acids derived from deoxycholic acid, chenodeoxycholic acid and lithocholic acid
F Májer, R Sharma, C Mullins, L Keogh, S Phipps, S Duggan, D Kelleher, ...
Bioorganic & medicinal chemistry 22 (1), 256-268, 2014
382014
Design, synthesis, and pharmacological effects of a cyclization-activated steroid prodrug for colon targeting in inflammatory bowel disease
JFM Ruiz, G Radics, H Windle, HO Serra, AL Simplício, K Kedziora, ...
Journal of medicinal chemistry 52 (10), 3205-3211, 2009
382009
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