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Alexey Strokach
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Fast and flexible protein design using deep graph neural networks
A Strokach, D Becerra, C Corbi-Verge, A Perez-Riba, PM Kim
Cell systems 11 (4), 402-411. e4, 2020
2682020
Deep generative modeling for protein design
A Strokach, PM Kim
Current opinion in structural biology 72, 226-236, 2022
992022
ELASPIC web-server: proteome-wide structure-based prediction of mutation effects on protein stability and binding affinity
DK Witvliet, A Strokach, AF Giraldo-Forero, J Teyra, R Colak, PM Kim
Bioinformatics 32 (10), 1589-1591, 2016
882016
A universal deep-learning model for zinc finger design enables transcription factor reprogramming
DM Ichikawa, O Abdin, N Alerasool, M Kogenaru, AL Mueller, H Wen, ...
Nature Biotechnology 41 (8), 1117-1129, 2023
512023
Predicting changes in protein stability caused by mutation using sequence‐and structure‐based methods in a CAGI5 blind challenge
A Strokach, C Corbi‐Verge, PM Kim
Human mutation 40 (9), 1414-1423, 2019
372019
ELASPIC2 (EL2): combining contextualized language models and graph neural networks to predict effects of mutations
A Strokach, TY Lu, PM Kim
Journal of molecular biology 433 (11), 166810, 2021
362021
Predicting the effect of mutations on protein folding and protein-protein interactions
A Strokach, C Corbi-Verge, J Teyra, PM Kim
Computational methods in protein evolution, 1-17, 2019
252019
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
Genome biology 25 (1), 53, 2024
242024
Evaluating the predictions of the protein stability change upon single amino acid substitutions for the FXN CAGI5 challenge
C Savojardo, M Petrosino, G Babbi, S Bovo, C Corbi‐Verge, R Casadio, ...
Human mutation 40 (9), 1392-1399, 2019
202019
Computational generation of proteins with predetermined three-dimensional shapes using ProteinSolver
A Strokach, D Becerra, C Corbi-Verge, A Perez-Riba, PM Kim
STAR protocols 2 (2), 100505, 2021
52021
System and method for generating a protein sequence
AV STROKACH, DB ROMERO, CC VERGE, AP Riba
US Patent App. 17/781,805, 2022
12022
Assessing the predicted impact of single amino acid substitutions in calmodulin for CAGI6 challenges
P Turina, G Dal Cortivo, CA Enriquez Sandoval, E Alexov, DB Ascher, ...
Human Genetics, 1-13, 2024
2024
Assessing predictions on fitness effects of missense variants in HMBS in CAGI6
J Zhang, L Kinch, P Katsonis, O Lichtarge, M Jagota, YS Song, Y Sun, ...
Human genetics, 1-17, 2024
2024
Machine learning approaches for structure-guided protein design
A Strokach
University of Toronto (Canada), 2024
2024
PROBING THE OLIGOMERIC STATUS OF G PROTEIN-COUPLED RECEPTORS BY SINGLE-MOLECULE FLUORESCENCE
AV Strokach, JW Wells
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION 33 (3), 203-203, 2013
2013
Probing the Oligomeric Status of G Protein-Coupled Receptors by Forster Resonance Energy Transfer and Single-Particle Fluorescence
A Strokach
2013
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Articles 1–16