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Nelson Y. S. Lam
Nelson Y. S. Lam
Research Fellow at the University of Cambridge
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
Achieving site-selectivity for C–H activation processes based on distance and geometry: a carpenter’s approach
G Meng, NYS Lam, EL Lucas, TG Saint-Denis, P Verma, N Chekshin, ...
Journal of the American Chemical Society 142 (24), 10571-10591, 2020
2422020
Advancing the logic of chemical synthesis: C− H activation as strategic and tactical disconnections for C− C bond construction
NYS Lam, K Wu, JQ Yu
Angewandte Chemie 133 (29), 15901-15924, 2021
2162021
From Catalysis to Cancer: Toward Structure–Activity Relationships for Benzimidazol-2-ylidene-Derived N-Heterocyclic-Carbene Complexes as Anticancer Agents
NYS Lam, D Truong, H Burmeister, MV Babak, HU Holtkamp, ...
Inorganic chemistry 57 (22), 14427-14434, 2018
632018
A directive Ni catalyst overrides conventional site selectivity in pyridine C–H alkenylation
T Zhang, YX Luan, NYS Lam, JF Li, Y Li, M Ye, JQ Yu
Nature chemistry 13 (12), 1207-1213, 2021
622021
Palladium-Catalyzed Enantioselective β-C(sp3)–H Activation Reactions of Aliphatic Acids: A Retrosynthetic Surrogate for Enolate Alkylation and Conjugate Addition
EL Lucas, NYS Lam, Z Zhuang, HSS Chan, DA Strassfeld, JQ Yu
Accounts of chemical research 55 (4), 537-550, 2022
562022
Unexpected arene ligand exchange results in the oxidation of an organoruthenium anticancer agent: the first X-ray structure of a protein–Ru (carbene) adduct
MP Sullivan, MK Nieuwoudt, GA Bowmaker, NYS Lam, D Truong, ...
Chemical communications 54 (48), 6120-6123, 2018
40*2018
Challenges and discoveries in the total synthesis of complex polyketide natural products
I Paterson, NYS Lam
The Journal of Antibiotics 71 (2), 215-233, 2018
382018
Molecular editing of aza-arene C–H bonds by distance, geometry and chirality
Z Fan, X Chen, K Tanaka, HS Park, NYS Lam, JJ Wong, KN Houk, JQ Yu
Nature 610 (7930), 87-93, 2022
332022
Empirical guidelines for the development of remote directing templates through quantitative and experimental analyses
NYS Lam, Z Fan, K Wu, HS Park, SY Shim, DA Strassfeld, JQ Yu
Journal of the American Chemical Society 144 (6), 2793-2803, 2022
302022
A synthesis-enabled relative stereochemical assignment of the C1–C28 region of hemicalide
BY Han, NYS Lam, CI MacGregor, JM Goodman, I Paterson
Chemical communications 54 (26), 3247-3250, 2018
272018
Synergism of anisotropic and computational NMR methods reveals the likely configuration of phormidolide A
IE Ndukwe, X Wang, NYS Lam, K Ermanis, KL Alexander, MJ Bertin, ...
Chemical communications 56 (55), 7565-7568, 2020
242020
The stereocontrolled total synthesis of polyketide natural products: a thirty-year journey
TP Stockdale, NYS Lam, MJ Anketell, I Paterson
Bulletin of the Chemical Society of Japan 94 (2), 713-731, 2021
222021
A counterintuitive stereochemical outcome from a chelation-controlled vinylmetal aldehyde addition leads to the configurational reassignment of phormidolide A
NYS Lam, G Muir, VR Challa, R Britton, I Paterson
Chemical communications 55 (65), 9717-9720, 2019
222019
An enantioselective Suzuki–Miyaura coupling to form axially chiral biphenols
R Pearce-Higgins, LN Hogenhout, PJ Docherty, DM Whalley, ...
Journal of the American Chemical Society 144 (33), 15026-15032, 2022
182022
Analysis of ruthenium anticancer agents by MEEKC‐UV and MEEKC–ICP‐MS: Impact of structural motifs on lipophilicity and biological activity
K Giringer, HU Holtkamp, S Movassaghi, WDJ Tremlett, NYS Lam, ...
Electrophoresis 39 (9-10), 1201-1207, 2018
182018
Quinoline-para-quinones and metals: coordination-assisted formation of quinoline-ortho-quinones
M Kubanik, NYS Lam, HU Holtkamp, T Söhnel, RF Anderson, ...
Chemical Communications, 2018
162018
Mechanistic Study of Enantioselective Pd-Catalyzed C(sp3)–H Activation of Thioethers Involving Two Distinct Stereomodels
TG Saint-Denis, NYS Lam, N Chekshin, PF Richardson, JS Chen, ...
ACS catalysis 11 (15), 9738-9753, 2021
152021
Stereocontrolled synthesis as an enabling tool for the configurational assignment of marine polyketide natural products
NYS Lam, I Paterson
European Journal of Organic Chemistry 2020 (16), 2310-2320, 2020
112020
Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents
TR Pettigrew, RJ Porter, SJ Walsh, MP Housden, NYS Lam, JS Carroll, ...
Chemical communications 56 (10), 1529-1532, 2020
112020
Conquering peaks and illuminating depths: developing stereocontrolled organic reactions to unlock nature's macrolide treasure trove
NYS Lam, TP Stockdale, MJ Anketell, I Paterson
Chemical Communications 57 (26), 3171-3189, 2021
102021
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Articles 1–20