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James Wells
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Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro
JR Spence, CN Mayhew, SA Rankin, MF Kuhar, JE Vallance, K Tolle, ...
Nature 470 (7332), 105-109, 2011
19552011
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
KW McCracken, EM Catá, CM Crawford, KL Sinagoga, M Schumacher, ...
Nature 516 (7531), 400-404, 2014
9902014
Vertebrate endoderm development and organ formation
AM Zorn, JM Wells
Annual Review of Cell and Developmental 25, 221-251, 2009
8892009
In vitro generation of human pluripotent stem cell derived lung organoids
BR Dye, DR Hill, MAH Ferguson, YH Tsai, MS Nagy, R Dyal, JM Wells, ...
elife 4, e05098, 2015
7552015
Vertebrate endoderm development
JM Wells, DA Melton
Annual review of cell and developmental biology 15 (1), 393-410, 1999
7151999
Engineered human pluripotent-stem-cell-derived intestinal tissues with a functional enteric nervous system
MJ Workman, MM Mahe, S Trisno, HM Poling, CL Watson, N Sundaram, ...
Nature medicine 23 (1), 49-59, 2017
5642017
An in vivo model of human small intestine using pluripotent stem cells
CL Watson, MM Mahe, J Múnera, JC Howell, N Sundaram, HM Poling, ...
Nature medicine 20 (11), 1310-1314, 2014
5552014
Early mouse endoderm is patterned by soluble factors from adjacent germ layers
JM Wells, DA Melton
Development 127 (8), 1563-1572, 2000
5452000
Generating human intestinal tissue from pluripotent stem cells in vitro
KW McCracken, JC Howell, JM Wells, JR Spence
Nature protocols 6 (12), 1920-1928, 2011
4482011
Sox17 and Sox4 differentially regulate β-catenin/T-cell factor activity and proliferation of colon carcinoma cells
D Sinner, JJ Kordich, JR Spence, R Opoka, S Rankin, SCJ Lin, D Jonatan, ...
Molecular and cellular biology 27 (22), 7802-7815, 2007
3782007
Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung
AE Serls, S Doherty, P Parvatiyar, JM Wells, GH Deutsch
Oxford University Press for The Company of Biologists Limited 132 (1), 35-47, 2005
3722005
Modeling steatohepatitis in humans with pluripotent stem cell-derived organoids
R Ouchi, S Togo, M Kimura, T Shinozawa, M Koido, H Koike, ...
Cell metabolism 30 (2), 374-384. e6, 2019
3692019
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells
JR Spence, AW Lange, SCJ Lin, KH Kaestner, AM Lowy, I Kim, ...
Developmental cell 17 (1), 62-74, 2009
3342009
Organoids by design
T Takebe, JM Wells
Science 364 (6444), 956-959, 2019
2942019
Global expression analysis of gene regulatory pathways during endocrine pancreatic development
G Gu, JM Wells, D Dombkowski, F Preffer, B Aronow, DA Melton
Oxford University Press for The Company of Biologists Limited 131 (1), 165-179, 2004
2942004
Pluripotent stem cell-derived organoids: using principles of developmental biology to grow human tissues in a dish
HA McCauley, JM Wells
Development 144 (6), 958-962, 2017
2842017
Modelling human hepato-biliary-pancreatic organogenesis from the foregut–midgut boundary
H Koike, K Iwasawa, R Ouchi, M Maezawa, K Giesbrecht, N Saiki, ...
Nature 574 (7776), 112-116, 2019
2472019
Differentiation of human pluripotent stem cells into colonic organoids via transient activation of BMP signaling
JO Múnera, N Sundaram, SA Rankin, D Hill, C Watson, M Mahe, ...
Cell stem cell 21 (1), 51-64. e6, 2017
2422017
Transdifferentiation of ciliated cells during repair of the respiratory epithelium
KS Park, JM Wells, AM Zorn, SE Wert, VE Laubach, LG Fernandez, ...
American journal of respiratory cell and molecular biology 34 (2), 151-157, 2006
2382006
FGF signaling is necessary for establishing gut tube domains alongthe anterior–posterior axis in vivo
J Dessimoz, R Opoka, JJ Kordich, A Grapin-Botton, JM Wells
Mechanisms of development 123 (1), 42-55, 2006
2372006
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Articles 1–20