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Juliet Mwirigi
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Neuropathic pain creates an enduring prefrontal cortex dysfunction corrected by the type II diabetic drug metformin but not by gabapentin
S Shiers, G Pradhan, J Mwirigi, G Mejia, A Ahmad, S Kroener, T Price
Journal of Neuroscience 38 (33), 7337-7350, 2018
772018
Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK
S Shiers, J Mwirigi, G Pradhan, M Kume, B Black, P Barragan-Iglesias, ...
Neuropsychopharmacology 45 (3), 524-533, 2020
452020
A pharmacological interactome between COVID-19 patient samples and human sensory neurons reveals potential drivers of neurogenic pulmonary dysfunction
PR Ray, A Wangzhou, N Ghneim, MS Yousuf, C Paige, ...
Brain, behavior, and immunity 89, 559-568, 2020
422020
The cellular basis of protease-activated receptor 2–evoked mechanical and affective pain
SN Hassler, M Kume, JM Mwirigi, A Ahmad, S Shiers, A Wangzhou, ...
JCI insight 5 (11), 2020
252020
Harmonized cross-species cell atlases of trigeminal and dorsal root ganglia
SA Bhuiyan, M Xu, L Yang, E Semizoglou, P Bhatia, KI Pantaleo, ...
bioRxiv, 2023
102023
A role for protease activated receptor type 3 (PAR3) in nociception demonstrated through development of a novel peptide agonist
J Mwirigi, M Kume, SN Hassler, A Ahmad, PR Ray, C Jiang, ...
The journal of pain 22 (6), 692-706, 2021
92021
MNK inhibitor eFT508 (Tomivosertib) suppresses ectopic activity in human dorsal root ganglion neurons from dermatomes with radicular neuropathic pain
Y Li, ML Uhelski, RY North, JM Mwirigi, CE Tatsui, JP Cata, G Corrales, ...
bioRxiv, 2023
42023
Inducible co-stimulatory molecule (ICOS) alleviates paclitaxel-induced neuropathic pain via an IL-10-mediated mechanism in female mice
I Sankaranarayanan, D Tavares-Ferreira, JM Mwirigi, GL Mejia, ...
Journal of Neuroinflammation 20 (1), 32, 2023
42023
Meteorin alleviates paclitaxel-induced peripheral neuropathic pain in mice
I Sankaranarayanan, D Tavares-Ferreira, L He, M Kume, JM Mwirigi, ...
The Journal of Pain 24 (4), 555-567, 2023
22023
RNA isoform expression landscape of the human dorsal root ganglion (DRG) generated from long read sequencing
A Arendt-Tranholm, JM Mwirigi, TJ Price
bioRxiv, 2023
12023
Oncostatin M induces nociceptive signaling in human dorsal root ganglia
J Mwirigi, UM Franco-Enzastiga, I Sankaranarayanan, D Tavares-Ferreira, ...
The Journal of Pain 24 (4), 16, 2023
12023
Exploring the Single-Cell Transcriptome Landscape of the Human Dorsal Root Ganglion in Diabetic Peripheral Neuropathy
I Sankaranarayanan, JM Mwirigi, NN Inturi, D Tavares-Ferreira, TJ Price
The Journal of Pain 25 (4), 26, 2024
2024
Protocol for long read sequencing of dorsal root ganglia from human organ donors
A Arendt-Tranholm, JM Mwirigi, T Price
2024
Elevations in the Mitochondrial Matrix Protein Cyclophilin D Correlate With Reduced Parvalbumin Expression in the Prefrontal Cortex of Patients With Schizophrenia
JT O’Brien, SP Jalilvand, NA Suji, RK Jupelly, A Phensy, JM Mwirigi, ...
Schizophrenia Bulletin, sbae016, 2024
2024
Interleukin-6 induces nascent protein synthesis in human DRG nociceptors via MNK-eIF4E signaling
ME Mitchell, G Torrijos, LF Cook, JM Mwirigi, L He, S Shiers, TJ Price
bioRxiv, 2024.04. 04.588080, 2024
2024
Genetic editing of primary human dorsal root ganglion neurons using CRISPR-Cas9 with functional confirmation
SM Palomino, K Gabriel, J Mwirigi, A Cervantes, P Horton, G Funk, ...
bioRxiv, 2024.04. 02.587857, 2024
2024
Epigenomic landscape of the human dorsal root ganglion: sex differences and transcriptional regulation of nociceptive genes
Ú Franco-Enzástiga, NN Inturi, K Natarajan, JM Mwirigi, K Mazhar, ...
bioRxiv, 2024.03. 27.587047, 2024
2024
VLK drives extracellular phosphorylation of EphB2 to govern the EphB2-NMDAR interaction and injury-induced pain
KD Srikanth, H Elahi, P Chander, HR Washburn, S Hassler, JM Mwirigi, ...
bioRxiv, 2024.03. 18.585314, 2024
2024
The mitochondrial matrix protein cyclophilin D contributes to deficits in parvalbumin interneurons in schizophrenia
JT O'Brien, SP Jalilvand, NA Suji, A Phensy, RK Jupelly, JM Mwirigi, ...
bioRxiv, 2023.05. 19.541499, 2023
2023
Meteorin alleviates Paclitaxel-induced peripheral neuropathy in mice
I Sankaranarayanan, D Tavares-Ferreira, L He, M Kume, J Mwirigi, ...
bioRxiv, 2022.09. 13.507857, 2022
2022
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