Michael A Colman
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3D virtual human atria: A computational platform for studying clinical atrial fibrillation
OV Aslanidi, MA Colman, J Stott, H Dobrzynski, MR Boyett, AV Holden, ...
Progress in biophysics and molecular biology 107 (1), 156-168, 2011
Pro‐arrhythmogenic effects of atrial fibrillation‐induced electrical remodelling: insights from the three‐dimensional virtual human atria
MA Colman, OV Aslanidi, S Kharche, MR Boyett, C Garratt, JC Hancox, ...
The Journal of physiology 591 (17), 4249-4272, 2013
Slow conduction in the border zones of patchy fibrosis stabilizes the drivers for atrial fibrillation: insights from multi-scale human atrial modeling
R Morgan, MA Colman, H Chubb, G Seemann, OV Aslanidi
Frontiers in physiology 7, 474, 2016
Heterogeneous and anisotropic integrative model of pulmonary veins: computational study of arrhythmogenic substrate for atrial fibrillation
OV Aslanidi, MA Colman, M Varela, J Zhao, BH Smaill, JC Hancox, ...
Interface focus 3 (2), 20120069, 2013
A computational model of spatio-temporal cardiac intracellular calcium handling with realistic structure and spatial flux distribution from sarcoplasmic reticulum and t-tubule …
MA Colman, C Pinali, AW Trafford, H Zhang, A Kitmitto
PLoS computational biology 13 (8), e1005714, 2017
Atrial heterogeneity generates re-entrant substrate during atrial fibrillation and anti-arrhythmic drug action: mechanistic insights from canine atrial models
M Varela, MA Colman, JC Hancox, OV Aslanidi
PLoS computational biology 12 (12), e1005245, 2016
Evolution and pharmacological modulation of the arrhythmogenic wave dynamics in canine pulmonary vein model
MA Colman, M Varela, JC Hancox, H Zhang, OV Aslanidi
Europace 16 (3), 416-423, 2014
Virtual tissue engineering of the human atrium: Modelling pharmacological actions on atrial arrhythmogenesis
OV Aslanidi, M Al-Owais, AP Benson, M Colman, CJ Garratt, SH Gilbert, ...
European journal of pharmaceutical sciences 46 (4), 209-221, 2012
Correlation between P-wave morphology and origin of atrial focal tachycardia—insights from realistic models of the human atria and torso
MA Colman, OV Aslanidi, J Stott, AV Holden, H Zhang
IEEE Transactions on Biomedical Engineering 58 (10), 2952-2955, 2011
Three-dimensional and chemical mapping of intracellular signaling nanodomains in health and disease with enhanced expansion microscopy
TMD Sheard, ME Hurley, J Colyer, E White, R Norman, E Pervolaraki, ...
ACS nano 13 (2), 2143-2157, 2019
In silico assessment of genetic variation in KCNA5 reveals multiple mechanisms of human atrial arrhythmogenesis
MA Colman, H Ni, B Liang, N Schmitt, H Zhang
PLoS computational biology 13 (6), e1005587, 2017
Effects of human atrial ionic remodelling by β-blocker therapy on mechanisms of atrial fibrillation: a computer simulation
SR Kharche, T Stary, MA Colman, IV Biktasheva, AJ Workman, AC Rankin, ...
Europace 16 (10), 1524-1533, 2014
A new algorithm to diagnose Atrial ectopic origin from multi lead ECG systems-insights from 3D virtual human Atria and Torso
EAP Alday, MA Colman, P Langley, TD Butters, J Higham, AJ Workman, ...
PLoS computational biology 11 (1), e1004026, 2015
Arrhythmia mechanisms and spontaneous calcium release: Bi-directional coupling between re-entrant and focal excitation
MA Colman
PLoS computational biology 15 (8), e1007260, 2019
Comparison of electric-and magnetic-cardiograms produced by myocardial ischemia in models of the human ventricle and torso
EAP Alday, H Ni, C Zhang, MA Colman, Z Gan, H Zhang
PLoS One 11 (8), e0160999, 2016
Human atrial arrhythmogenesis and sinus bradycardia in KCNQ1-linked short QT syndrome: insights from computational modelling
DG Whittaker, MA Colman, H Ni, JC Hancox, H Zhang
Frontiers in physiology 9, 1402, 2018
Dynamic clamping human and rabbit atrial calcium current: narrowing ICaL window abolishes early afterdepolarizations
S Kettlewell, P Saxena, J Dempster, MA Colman, RC Myles, GL Smith, ...
The Journal of physiology 597 (14), 3619-3638, 2019
Trigger vs. substrate: multi-dimensional modulation of QT-prolongation associated arrhythmic dynamics by a hERG channel activator
MA Colman, EA Perez Alday, AV Holden, AP Benson
Frontiers in physiology, 757, 2017
Recent progress in multi-scale models of the human atria
MA Colman, SJ Castro, EAP Alday, JC Hancox, C Garratt, H Zhang
Drug Discovery Today: Disease Models 14, 23-32, 2014
Mechanisms of Atrial Arrhythmias
MA Colman
Mechanisms of Atrial Arrhythmias: Insights from the Development of a …, 2014
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