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John Paul Shen
John Paul Shen
Assistant Professor, University of Texas MD Anderson Cancer Center
Verified email at alum.mit.edu - Homepage
Title
Cited by
Cited by
Year
Integrated genomic characterization of papillary thyroid carcinoma
N Agrawal, R Akbani, BA Aksoy, A Ally, H Arachchi, SL Asa, JT Auman, ...
Cell 159 (3), 676-690, 2014
24572014
Network-based stratification of tumor mutations
M Hofree, JP Shen, H Carter, A Gross, T Ideker
Nature methods 10 (11), 1108-1115, 2013
8702013
Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions
JP Shen, D Zhao, R Sasik, J Luebeck, A Birmingham, ...
Nature methods 14 (6), 573-576, 2017
3582017
Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease
JE Bradner, R Mak, SK Tanguturi, R Mazitschek, SJ Haggarty, K Ross, ...
Proceedings of the National Academy of Sciences 107 (28), 12617-12622, 2010
2312010
Novel third-generation EGFR tyrosine kinase inhibitors and strategies to overcome therapeutic resistance in lung cancer
A Murtuza, A Bulbul, JP Shen, P Keshavarzian, BD Woodward, ...
Cancer Research 79 (4), 689-698, 2019
1742019
Genetic interaction mapping in mammalian cells using CRISPR interference
D Du, A Roguev, DE Gordon, M Chen, SH Chen, M Shales, JP Shen, ...
Nature methods 14 (6), 577-580, 2017
1652017
A network of conserved synthetic lethal interactions for exploration of precision cancer therapy
R Srivas, JP Shen, CC Yang, SM Sun, J Li, AM Gross, J Jensen, K Licon, ...
Molecular cell 63 (3), 514-525, 2016
1602016
A robust small-molecule microarray platform for screening cell lysates
JE Bradner, OM McPherson, R Mazitschek, D Barnes-Seeman, JP Shen, ...
Chemistry & biology 13 (5), 493-504, 2006
1562006
A global transcriptional network connecting noncoding mutations to changes in tumor gene expression
W Zhang, A Bojorquez-Gomez, DO Velez, G Xu, KS Sanchez, JP Shen, ...
Nature genetics 50 (4), 613-620, 2018
1452018
Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss
AM Gross, RK Orosco, JP Shen, AM Egloff, H Carter, M Hofree, ...
Nature genetics 46 (9), 939-943, 2014
1422014
Few-shot learning creates predictive models of drug response that translate from high-throughput screens to individual patients
J Ma, SH Fong, Y Luo, CJ Bakkenist, JP Shen, S Mourragui, LFA Wessels, ...
Nature Cancer 2 (2), 233-244, 2021
1032021
Phase 1/2 study of ARV-110, an androgen receptor (AR) PROTAC degrader, in metastatic castration-resistant prostate cancer (mCRPC).
X Gao, HA Burris III, J Vuky, R Dreicer, AO Sartor, CN Sternberg, ...
Journal of Clinical Oncology 40 (6_suppl), 17-17, 2022
752022
Relative abundance of SARS-CoV-2 entry genes in the enterocytes of the lower gastrointestinal tract
JJ Lee, S Kopetz, E Vilar, JP Shen, K Chen, A Maitra
Genes 11 (6), 645, 2020
692020
Patient-derived micro-organospheres enable clinical precision oncology
S Ding, C Hsu, Z Wang, NR Natesh, R Millen, M Negrete, N Giroux, ...
Cell Stem Cell 29 (6), 905-917. e6, 2022
642022
Phase I/II trial of encorafenib, cetuximab, and nivolumab in patients with microsatellite stable, BRAFV600E metastatic colorectal cancer.
VK Morris, CM Parseghian, M Escano, B Johnson, KPS Raghav, A Dasari, ...
Journal of Clinical Oncology 40 (4_suppl), 12-12, 2022
572022
Genomic landscape of appendiceal neoplasms
CSP Ang, JP Shen, CJ Hardy-Abeloos, JK Huang, JS Ross, VA Miller, ...
JCO Precision Oncology 2, 1-18, 2018
572018
Disruption of NSD1 in Head and Neck Cancer Promotes Favorable Chemotherapeutic Responses Linked to Hypomethylation
N Bui, JK Huang, A Bojorquez-Gomez, K Licon, KS Sanchez, SN Tang, ...
Molecular cancer therapeutics 17 (7), 1585-1594, 2018
532018
Comprehensive Clinical and Molecular Characterization of KRASG12C-Mutant Colorectal Cancer
JT Henry, O Coker, S Chowdhury, JP Shen, VK Morris, A Dasari, ...
JCO Precision Oncology 5, 613-621, 2021
502021
Clinical and Molecular Characterization of POLE Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers
B Garmezy, J Gheeya, HY Lin, Y Huang, T Kim, X Jiang, KZ Thein, ...
JCO Precision Oncology 6, e2100267, 2022
392022
Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression
S Cao, JR Wang, S Ji, P Yang, Y Dai, S Guo, MD Montierth, JP Shen, ...
Nature biotechnology 40 (11), 1624-1633, 2022
382022
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