| Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes CE Nestor, R Ottaviano, J Reddington, D Sproul, D Reinhardt, D Dunican, ... Genome research 22 (3), 467-477, 2012 | 363 | 2012 |
| Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA. C Nestor, A Ruzov, RR Meehan, DS Dunican Biotechniques 48 (4), 317-319, 2010 | 231 | 2010 |
| Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes JP Reddington, SM Perricone, CE Nestor, J Reichmann, NA Youngson, ... Genome biology 14 (3), 1-17, 2013 | 200 | 2013 |
| Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer D Sproul, C Nestor, J Culley, JH Dickson, JM Dixon, DJ Harrison, ... Proceedings of the National Academy of Sciences 108 (11), 4364-4369, 2011 | 161 | 2011 |
| Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns D Sproul, RR Kitchen, CE Nestor, JM Dixon, AH Sims, DJ Harrison, ... Genome biology 13 (10), 1-16, 2012 | 153 | 2012 |
| Modules, networks and systems medicine for understanding disease and aiding diagnosis M Gustafsson, CE Nestor, H Zhang, AL Barabási, S Baranzini, S Brunak, ... Genome medicine 6 (10), 1-11, 2014 | 151 | 2014 |
| Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems CE Nestor, R Ottaviano, D Reinhardt, HA Cruickshanks, HK Mjoseng, ... Genome biology 16 (1), 1-17, 2015 | 144 | 2015 |
| Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline JA Hackett, JP Reddington, CE Nestor, DS Dunican, MR Branco, ... Development 139 (19), 3623-3632, 2012 | 134 | 2012 |
| Profiling of human CD4+ T-cell subsets identifies the TH2-specific noncoding RNA GATA3-AS1 H Zhang, CE Nestor, S Zhao, A Lentini, B Bohle, M Benson, H Wang Journal of Allergy and Clinical Immunology 132 (4), 1005-1008, 2013 | 78 | 2013 |
| Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome JP Thomson, H Lempiäinen, JA Hackett, CE Nestor, A Müller, F Bolognani, ... Genome biology 13 (10), 1-17, 2012 | 78 | 2012 |
| Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise NC Whitelaw, S Chong, DK Morgan, C Nestor, TJ Bruxner, A Ashe, ... Genome biology 11 (11), 1-10, 2010 | 62 | 2010 |
| DNA methylation changes separate allergic patients from healthy controls and may reflect altered CD4+ T-cell population structure CE Nestor, F Barrenäs, H Wang, A Lentini, H Zhang, S Bruhn, R Jörnsten, ... PLoS Genet 10 (1), e1004059, 2014 | 61 | 2014 |
| A validated gene regulatory network and GWAS identifies early regulators of T cell–associated diseases M Gustafsson, DR Gawel, L Alfredsson, S Baranzini, J Björkander, ... Science translational medicine 7 (313), 313ra178-313ra178, 2015 | 54 | 2015 |
| A reassessment of DNA-immunoprecipitation-based genomic profiling A Lentini, C Lagerwall, S Vikingsson, HK Mjoseng, K Douvlataniotis, ... Nature methods 15 (7), 499-504, 2018 | 49 | 2018 |
| 5-Hydroxymethylcytosine remodeling precedes lineage specification during differentiation of human CD4+ T cells CE Nestor, A Lentini, CH Nilsson, DR Gawel, M Gustafsson, L Mattson, ... Cell reports 16 (2), 559-570, 2016 | 48 | 2016 |
| Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques JP Thomson, JM Hunter, CE Nestor, DS Dunican, R Terranova, JG Moggs, ... Nucleic acids research 41 (22), e206-e206, 2013 | 46 | 2013 |
| TCF/LEF dependent and independent transcriptional regulation of Wnt/β‐catenin target genes N Doumpas, F Lampart, MD Robinson, A Lentini, CE Nestor, C Cantù, ... The EMBO journal 38 (2), e98873, 2019 | 40 | 2019 |
| Dynamic response genes in CD4+ T cells reveal a network of interactive proteins that classifies disease activity in multiple sclerosis S Hellberg, D Eklund, DR Gawel, M Köpsén, H Zhang, CE Nestor, ... Cell reports 16 (11), 2928-2939, 2016 | 37 | 2016 |
| A generally applicable translational strategy identifies S100A4 as a candidate gene in allergy S Bruhn, Y Fang, F Barrenäs, M Gustafsson, H Zhang, A Konstantinell, ... Science translational medicine 6 (218), 218ra4-218ra4, 2014 | 36 | 2014 |
| Hydroxymethylated DNA immunoprecipitation (hmeDIP) CE Nestor, RR Meehan Functional analysis of DNA and chromatin, 259-267, 2014 | 32 | 2014 |
