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Fiona Simpkins
Fiona Simpkins
Geverifieerd e-mailadres voor uphs.upenn.edu
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Targeting the ATR/CHK1 Axis with PARP Inhibition Results in Tumor Regression in BRCA-Mutant Ovarian Cancer Models
H Kim, E George, RL Ragland, S Rafail, R Zhang, C Krepler, MA Morgan, ...
Clinical Cancer Research 23 (12), 3097-3108, 2017
2532017
Radiation therapy compared with pelvic node resection for node-positive vulvar cancer: a randomized controlled trial
C Kunos, F Simpkins, H Gibbons, C Tian, H Homesley
Obstetrics & Gynecology 114 (3), 537-546, 2009
2182009
Combining PARP with ATR inhibition overcomes PARP inhibitor and platinum resistance in ovarian cancer models
H Kim, H Xu, E George, D Hallberg, S Kumar, V Jagannathan, ...
Nature communications 11 (1), 3726, 2020
2112020
Visual working memory in primary generalized epilepsy: An18 FDG-PET study
BE Swartz, F Simpkins, E Halgren, M Mandelkern, C Brown, ...
Neurology 47 (5), 1203-1212, 1996
1821996
Proteomic analysis for the early detection and rational treatment of cancer—realistic hope?
EM Posadas, F Simpkins, LA Liotta, C MacDonald, EC Kohn
Annals of oncology 16 (1), 16-22, 2005
1622005
BET bromodomain inhibition synergizes with PARP inhibitor in epithelial ovarian cancer
S Karakashev, H Zhu, Y Yokoyama, B Zhao, N Fatkhutdinov, ...
Cell reports 21 (12), 3398-3405, 2017
1612017
A PET imaging agent for evaluating PARP-1 expression in ovarian cancer
M Makvandi, A Pantel, L Schwartz, E Schubert, K Xu, CJ Hsieh, C Hou, ...
The Journal of clinical investigation 128 (5), 2116-2126, 2018
1192018
Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer
CD Capo-chichi, KQ Cai, F Simpkins, P Ganjei-Azar, AK Godwin, XX Xu
BMC medicine 9, 1-12, 2011
1112011
Cortical metabolic activation in humans during a visual memory task
BE Swartz, E Halgren, JM Fuster, F Simpkins, M Gee, M Mandelkern
Cerebral Cortex 5 (3), 205-214, 1995
1111995
Avoiding bevacizumab related gastrointestinal toxicity for recurrent ovarian cancer by careful patient screening
F Simpkins, JL Belinson, PG Rose
Gynecologic oncology 107 (1), 118-123, 2007
1072007
RING domain–deficient BRCA1 promotes PARP inhibitor and platinum resistance
Y Wang, JJ Krais, AJ Bernhardy, E Nicolas, KQ Cai, MI Harrell, HH Kim, ...
The Journal of clinical investigation 126 (8), 3145-3157, 2016
922016
Lysophosphatidic acid and endothelin-induced proliferation of ovarian cancer cell lines is mitigated by neutralization of granulin–epithelin precursor (GEP), a prosurvival …
M Kamrava, F Simpkins, E Alejandro, C Michener, E Meltzer, EC Kohn
Oncogene 24 (47), 7084-7093, 2005
882005
Cisplatin resistance in human cervical, ovarian and lung cancer cells
J Chen, C Solomides, H Parekh, F Simpkins, H Simpkins
Cancer chemotherapy and pharmacology 75, 1217-1227, 2015
872015
New insights on the role of hormonal therapy in ovarian cancer
F Simpkins, A Garcia-Soto, J Slingerland
Steroids 78 (6), 530-537, 2013
792013
VEGFA activates an epigenetic pathway upregulating ovarian cancer‐initiating cells
K Jang, M Kim, CA Gilbert, F Simpkins, TA Ince, JM Slingerland
EMBO molecular medicine 9 (3), 304-318, 2017
712017
A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers
E George, H Kim, C Krepler, B Wenz, M Makvandi, JL Tanyi, E Brown, ...
JCI insight 2 (1), 2017
702017
Dual Src and MEK inhibition decreases ovarian cancer growth and targets tumor initiating stem-like cells
F Simpkins, K Jang, H Yoon, KE Hew, M Kim, DJ Azzam, J Sun, D Zhao, ...
Clinical cancer research 24 (19), 4874-4886, 2018
672018
SELDI-TOF mass spectrometry for cancer biomarker discovery and serum proteomic diagnostics
F Simpkins, JA Czechowicz, L Liotta, EC Kohn
Future Medicine Ltd 6 (6), 647-653, 2005
642005
Improved Sensitivity of 18FDG‐Positron Emission Tomography Scans in Frontal and “Frontal Plus” Epilepsy
BE Swartz, A Khonsari, C Brown, M Mandelkern, F Simpkins, ...
Epilepsia 36 (4), 388-395, 1995
641995
Combination ATR and PARP Inhibitor (CAPRI): A phase 2 study of ceralasertib plus olaparib in patients with recurrent, platinum-resistant epithelial ovarian cancer
PD Shah, SL Wethington, C Pagan, N Latif, J Tanyi, LP Martin, M Morgan, ...
Gynecologic oncology 163 (2), 246-253, 2021
612021
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Artikelen 1–20