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Christopher McCrae
Christopher McCrae
Principal Scientist, Translational Science & Experimental Medicine, BioPharmaceuticals R&D
Verified email at astrazeneca.com
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Cited by
Cited by
Year
Dynamics of IFN-β responses during respiratory viral infection. Insights for therapeutic strategies
A Watson, CM Spalluto, C McCrae, D Cellura, H Burke, D Cunoosamy, ...
American journal of respiratory and critical care medicine 201 (1), 83-94, 2020
642020
Budesonide and formoterol effects on rhinovirus replication and epithelial cell cytokine responses
YA Bochkov, WW Busse, RA Brockman-Schneider, MD Evans, NN Jarjour, ...
Respiratory research 14, 1-9, 2013
502013
Upper airway cell transcriptomics identify a major new immunological phenotype with strong clinical correlates in young children with acute wheezing
SK Khoo, J Read, K Franks, G Zhang, J Bizzintino, L Coleman, C McCrae, ...
The Journal of Immunology 202 (6), 1845-1858, 2019
482019
Euodenine A: A small-molecule agonist of human TLR4
JE Neve, HP Wijesekera, S Duffy, ID Jenkins, JA Ripper, SJ Teague, ...
Journal of Medicinal Chemistry 57 (4), 1252-1275, 2014
472014
Using novel computed tomography analysis to describe the contribution and distribution of emphysema and small airways disease in chronic obstructive pulmonary disease
K Ostridge, K Gove, KHW Paas, H Burke, A Freeman, S Harden, M Kirby, ...
Annals of the American Thoracic Society 16 (8), 990-997, 2019
442019
Attached stratified mucus separates bacteria from the epithelial cells in COPD lungs
JA Fernández-Blanco, D Fakih, L Arike, AM Rodríguez-Piñeiro, ...
JCI insight 3 (17), 2018
442018
Type 2 inflammation in eosinophilic chronic obstructive pulmonary disease
A Higham, A Beech, S Wolosianka, N Jackson, G Long, U Kolsum, ...
Allergy 76 (6), 1861, 2021
382021
Seasonal and geographic variations in the incidence of asthma exacerbations in the United States
M Gerhardsson de Verdier, P Gustafson, C McCrae, S Edsbäcker, ...
Journal of Asthma 54 (8), 818-824, 2017
352017
Colds as predictors of the onset and severity of COPD exacerbations
NW Johnston, M Olsson, S Edsbäcker, M Gerhardsson de Verdier, ...
International Journal of Chronic Obstructive Pulmonary Disease, 839-848, 2017
262017
Development of a high-throughput human rhinovirus infectivity cell-based assay for identifying antiviral compounds
T Phillips, L Jenkinson, C McCrae, B Thong, J Unitt
Journal of virological methods 173 (2), 182-188, 2011
212011
A novel class of small molecule agonists with preference for human over mouse TLR4 activation
JD Marshall, DS Heeke, E Rao, SK Maynard, D Hornigold, C McCrae, ...
PLoS One 11 (10), e0164632, 2016
192016
INEXAS: A Phase 2 Randomized Trial of On‐demand Inhaled Interferon Beta‐1a in Severe Asthmatics
C McCrae, M Olsson, P Gustafson, A Malmgren, M Aurell, M Fagerås, ...
Clinical & Experimental Allergy 51 (2), 273-283, 2021
162021
On-demand inhaled interferon-beta 1a for the prevention of severa asthma exacerbations: results of the INEXAS phase 2a study
C McCrae, M Olsson, M Aurell, C Lundin, J Paraskos, A Cavallin, ...
D12. IMMUNOTHERAPY IN LUNG DISEASE, A6165-A6165, 2018
152018
Lanosterol synthase regulates human rhinovirus replication in human bronchial epithelial cells
C McCrae, A Dzgoev, M Ståhlman, J Horndahl, R Svärd, A Große, ...
American Journal of Respiratory Cell and Molecular Biology 59 (6), 713-722, 2018
122018
Study on risk factors and phenotypes of acute exacerbations of chronic obstructive pulmonary disease in Guangzhou, China—design and baseline characteristics
Y Zhou, PLB Bruijnzeel, C McCrae, J Zheng, U Nihlen, R Zhou, ...
Journal of thoracic disease 7 (4), 720, 2015
102015
Increased mast cell activation in eosinophilic chronic obstructive pulmonary disease
A Higham, J Dungwa, TH Pham, C McCrae, D Singh
Clinical & translational immunology 11 (9), e1417, 2022
92022
Effect of lipophilicity modulation on inhibition of human rhinovirus capsid binders
A Morley, N Tomkinson, A Cook, C MacDonald, R Weaver, S King, ...
Bioorganic & medicinal chemistry letters 21 (20), 6031-6035, 2011
82011
Quantitative assessment of mucociliary clearance in smokers with mild-to-moderate chronic obstructive pulmonary disease and chronic bronchitis from planar radionuclide imaging …
JS Fleming, J Conway, MJ Bennett, L Tossici-Bolt, M Guy, FX Blé, ...
Journal of Aerosol Medicine and Pulmonary Drug Delivery 32 (4), 175-188, 2019
62019
Benralizumab versus Mepolizumab for Eosinophilic Granulomatosis with Polyangiitis
ME Wechsler, P Nair, B Terrier, B Walz, A Bourdin, DRW Jayne, ...
New England Journal of Medicine, 2024
52024
610 efficacy and safety of benralizumab in adults and adolescents with eosinophilic esophagitis: results from the 24-week double-blind period of the phase 3 messina trial
ME Rothenberg, ES Dellon, MH Collins, AJ Bredenoord, I Hirano, ...
Gastroenterology 164 (6), S-115, 2023
52023
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