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Alan D. Irvine
Alan D. Irvine
Trinity College Dublin; Children's Health Ireland
Verified email at tcd.ie - Homepage
Title
Cited by
Cited by
Year
Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis
CNA Palmer, AD Irvine, A Terron-Kwiatkowski, Y Zhao, H Liao, SP Lee, ...
Nature genetics 38 (4), 441-446, 2006
36192006
Filaggrin mutations associated with skin and allergic diseases
AD Irvine, WHI McLean, DYM Leung
New England Journal of Medicine 365 (14), 1315-1327, 2011
14072011
Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris
FJD Smith, AD Irvine, A Terron-Kwiatkowski, A Sandilands, LE Campbell, ...
Nature genetics 38 (3), 337-342, 2006
13042006
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
A Strange, F Capon, CC Spencer, J Knight, ME Weale, MH Allen, ...
Nat Genet 42 (11), 985-990, 2010
11032010
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
LC Tsoi, SL Spain, J Knight, E Ellinghaus, PE Stuart, F Capon, J Ding, ...
Nature Genetics, 2012
10452012
Filaggrin in the frontline: role in skin barrier function and disease
A Sandilands, C Sutherland, AD Irvine, WHI McLean
Journal of cell science 122 (9), 1285-1294, 2009
10252009
Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome
S Chavanas, C Bodemer, A Rochat, D Hamel-Teillac, M Ali, AD Irvine, ...
Nature genetics 25 (2), 141-142, 2000
10182000
Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema
A Sandilands, A Terron-Kwiatkowski, PR Hull, GM O'Regan, TH Clayton, ...
Nature genetics 39 (5), 650-654, 2007
7932007
Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations
S Weidinger, T Illig, H Baurecht, AD Irvine, E Rodriguez, A Diaz-Lacava, ...
Journal of Allergy and Clinical Immunology 118 (1), 214-219, 2006
7562006
Filaggrin in atopic dermatitis
GM O'Regan, A Sandilands, WHI McLean, AD Irvine
Journal of Allergy and Clinical Immunology 122 (4), 689-693, 2008
6702008
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
JS Ried, J Li, XB Zuo, XD Zheng, XY Yin, LD Sun, MA McAleer, ...
Nature genetics 47 (12), 1449-1456, 2015
5842015
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming
PG Fallon, T Sasaki, A Sandilands, LE Campbell, SP Saunders, ...
Nature genetics 41 (5), 602-608, 2009
5502009
Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy
SJ Brown, Y Asai, HJ Cordell, LE Campbell, Y Zhao, H Liao, K Northstone, ...
Journal of Allergy and Clinical Immunology 127 (3), 661-667, 2011
5342011
Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease
E Rodríguez, H Baurecht, E Herberich, S Wagenpfeil, SJ Brown, ...
Journal of Allergy and Clinical Immunology 123 (6), 1361-1370. e7, 2009
5232009
The multifunctional role of filaggrin in allergic skin disease
MA McAleer, AD Irvine
Journal of Allergy and Clinical Immunology 131 (2), 280-291, 2013
5222013
Filaggrin mutations, atopic eczema, hay fever, and asthma in children
S Weidinger, M O'Sullivan, T Illig, H Baurecht, M Depner, E Rodriguez, ...
Journal of Allergy and Clinical Immunology 121 (5), 1203-1209. e1, 2008
5142008
Human keratin diseases: the increasing spectrum of disease and subtlety of the phenotype–genotype correlation
AD Irvine, WHI McLean
British Journal of Dermatology 140 (5), 815-828, 1999
4661999
Hay–Wells syndrome is caused by heterozygous missense mutations in the SAM domain of p63
JA McGrath, PHG Duijf, V Doetsch, AD Irvine, R Waal, KRJ Vanmolkot, ...
Human molecular genetics 10 (3), 221-230, 2001
4602001
The microbiome in patients with atopic dermatitis
AS Paller, HH Kong, P Seed, S Naik, TC Scharschmidt, RL Gallo, T Luger, ...
Journal of Allergy and Clinical Immunology 143 (1), 26-35, 2019
4312019
The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study
J Henderson, K Northstone, SP Lee, H Liao, Y Zhao, M Pembrey, ...
Journal of Allergy and Clinical Immunology 121 (4), 872-877. e9, 2008
4292008
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