| G-quadruplex stabilizer 3, 6-bis (1-methyl-4-vinylpyridinium) carbazole diiodide induces accelerated senescence and inhibits tumorigenic properties in cancer cells FC Huang, CC Chang, PJ Lou, IC Kuo, CW Chien, CT Chen, FY Shieh, ... Molecular Cancer Research 6 (6), 955-964, 2008 | 68 | 2008 |
| Synthesis, cytotoxicity and human telomerase inhibition activities of a series of 1, 2-heteroannelated anthraquinones and anthra [1, 2-d] imidazole-6, 11-dione homologues HS Huang, TC Chen, RH Chen, KF Huang, FC Huang, JR Jhan, CL Chen, ... Bioorganic & medicinal chemistry 17 (21), 7418-7428, 2009 | 67 | 2009 |
| Synthesis and cytotoxic properties of 4, 11-bis [(aminoethyl) amino] anthra [2, 3-b] thiophene-5, 10-diones, novel analogues of antitumor anthracene-9, 10-diones AE Shchekotikhin, VA Glazunova, LG Dezhenkova, YN Luzikov, ... Bioorganic & medicinal chemistry 17 (5), 1861-1869, 2009 | 64 | 2009 |
| Activation of human telomerase reverse transcriptase expression by some new symmetrical bis-substituted derivatives of the anthraquinone HS Huang, JF Chiou, Y Fong, CC Hou, YC Lu, JY Wang, JW Shih, ... Journal of medicinal chemistry 46 (15), 3300-3307, 2003 | 62 | 2003 |
| Erlotinib-conjugated iron oxide nanoparticles as a smart cancer-targeted theranostic probe for MRI AAA Ali, FT Hsu, CL Hsieh, CY Shiau, CH Chiang, ZH Wei, CY Chen, ... Scientific reports 6 (1), 36650, 2016 | 60 | 2016 |
| Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2, 7-bis-substituted amido-anthraquinone derivatives HS Huang, KF Huang, CL Li, YY Huang, YH Chiang, FC Huang, JJ Lin Bioorganic & medicinal chemistry 16 (14), 6976-6986, 2008 | 60 | 2008 |
| Synthesis and human telomerase inhibition of a series of regioisomeric disubstituted amidoanthraquinones HS Huang, IB Chen, KF Huang, WC Lu, FY Shieh, YY Huang, FC Huang, ... Chemical and pharmaceutical bulletin 55 (2), 284-292, 2007 | 55 | 2007 |
| Induction of senescence in cancer cells by the G‐quadruplex stabilizer, BMVC4, is independent of its telomerase inhibitory activity FC Huang, CC Chang, JM Wang, TC Chang, JJ Lin British journal of pharmacology 167 (2), 393-406, 2012 | 54 | 2012 |
| Pharmacoinformatics and preclinical studies of nsc765690 and nsc765599, potential stat3/cdk2/4/6 inhibitors with antitumor activities against nci60 human tumor cell lines B Lawal, YL Liu, N Mokgautsi, H Khedkar, MR Sumitra, ATH Wu, ... Biomedicines 9 (01), 92, 2021 | 53 | 2021 |
| Inhibition of cancer cell migration and invasion through suppressing the Wnt1-mediating signal pathway by G-quadruplex structure stabilizers JM Wang, FC Huang, MHJ Kuo, ZF Wang, TY Tseng, LC Chang, SJ Yen, ... Journal of Biological Chemistry 289 (21), 14612-14623, 2014 | 53 | 2014 |
| mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 are druggable candidates for N-(2, 4-difluorophenyl)-2′, 4′-difluoro-4-hydroxybiphenyl-3-carboxamide (NSC765598), with consequent anticancer … B Lawal, CY Lee, N Mokgautsi, MR Sumitra, H Khedkar, ATH Wu, ... Frontiers in Oncology 11, 656738, 2021 | 52 | 2021 |
| Human telomerase inhibition and cytotoxicity of regioisomeric disubstituted amidoanthraquinones and aminoanthraquinones HS Huang, CL Chou, CL Guo, CL Yuan, YC Lu, FY Shieh, JJ Lin Bioorganic & medicinal chemistry 13 (5), 1435-1444, 2005 | 51 | 2005 |
| The first series of 4, 11-bis [(2-aminoethyl) amino] anthra [2, 3-b] furan-5, 10-diones: Synthesis and anti-proliferative characteristics AE Shchekotikhin, VA Glazunova, LG Dezhenkova, EK Shevtsova, ... European journal of medicinal chemistry 46 (1), 423-428, 2011 | 49 | 2011 |
| New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes KT Cheng, FL Hsu, SH Chen, PK Hsieh, HS Huang, CK Lee, MH Lee Chemical and pharmaceutical bulletin 55 (5), 757-761, 2007 | 48 | 2007 |
| Effects of cantharidinimides on human carcinoma cells LH Lin, HS Huang, CC Lin, LW Lee, PY Lin Chemical and pharmaceutical bulletin 52 (7), 855-857, 2004 | 47 | 2004 |
| Temporal expression patterns of distinct cytokines and M1/M2 macrophage polarization regulate rheumatoid arthritis progression CC Kung, SP Dai, H Chiang, HS Huang, WH Sun Molecular biology reports 47, 3423-3437, 2020 | 45 | 2020 |
| Structure-based design, synthesis and evaluation of novel anthra [1, 2-d] imidazole-6, 11-dione derivatives as telomerase inhibitors and potential for cancer polypharmacology CL Chen, DM Chang, TC Chen, CC Lee, HH Hsieh, FC Huang, KF Huang, ... European journal of medicinal chemistry 60, 29-41, 2013 | 41 | 2013 |
| Synthesis and structure–activity correlations of the cytotoxic bifunctional 1, 4-diamidoanthraquinone derivatives HS Huang, HF Chiu, AL Lee, CL Guo, CL Yuan Bioorganic & medicinal chemistry 12 (23), 6163-6170, 2004 | 41 | 2004 |
| Different roles of p53 in the regulation of DNA damage caused by 1, 2-heteroannelated anthraquinones and doxorubicin YL Chang, HJ Lee, ST Liu, YS Lin, TC Chen, TY Hsieh, HS Huang, ... The international journal of biochemistry & cell biology 43 (12), 1720-1728, 2011 | 39 | 2011 |
| TC-N19, a novel dual inhibitor of EGFR and cMET, efficiently overcomes EGFR-TKI resistance in non-small-cell lung cancer cells DW Wu, TC Chen, HS Huang, H Lee Cell death & disease 7 (6), e2290-e2290, 2016 | 38 | 2016 |
Chia-Chung LeeGraduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and TechnologyПодтвержден адрес электронной почты в домене tmu.edu.tw
