Gatien Moriceau
Gatien Moriceau
Assistant Professor at UCLA
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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF (V600E)
PI Poulikakos, Y Persaud, M Janakiraman, X Kong, C Ng, G Moriceau, ...
Nature 480 (7377), 387, 2011
Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy
H Shi, W Hugo, X Kong, A Hong, RC Koya, G Moriceau, T Chodon, R Guo, ...
Cancer discovery, 2013
Melanoma whole-exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance
H Shi, G Moriceau, X Kong, MK Lee, H Lee, RC Koya, C Ng, T Chodon, ...
Nature communications 3, 724, 2012
Non-genomic and immune evolution of melanoma acquiring MAPKi resistance
W Hugo, H Shi, L Sun, M Piva, C Song, X Kong, G Moriceau, A Hong, ...
Cell 162 (6), 1271-1285, 2015
MDM4 is a key therapeutic target in cutaneous melanoma
A Gembarska, F Luciani, C Fedele, EA Russell, M Dewaele, S Villar, ...
Nature medicine 18 (8), 1239, 2012
Tunable-combinatorial mechanisms of acquired resistance limit the efficacy of BRAF/MEK cotargeting but result in melanoma drug addiction
G Moriceau, W Hugo, A Hong, H Shi, X Kong, CY Clarissa, RC Koya, ...
Cancer cell 27 (2), 240-256, 2015
A novel AKT1 mutant amplifies an adaptive melanoma response to BRAF inhibition
H Shi, A Hong, X Kong, RC Koya, C Song, G Moriceau, W Hugo, ...
Cancer discovery, 2013
Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors
H Shi, G Moriceau, X Kong, RC Koya, R Nazarian, GM Pupo, ...
Cancer discovery, 2012
Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process
G Moriceau, B Ory, L Mitrofan, C Riganti, F Blanchard, R Brion, C Charrier, ...
Cancer Research, canres. 0578.2010, 2010
Recurrent tumor cell-intrinsic and-extrinsic alterations during MAPKi-induced melanoma regression and early adaptation
C Song, M Piva, L Sun, A Hong, G Moriceau, X Kong, H Zhang, S Lomeli, ...
Cancer discovery, CD-17-0401, 2017
Vemurafenib resistance reprograms melanoma cells towards glutamine dependence
JE Hernandez-Davies, TQ Tran, MA Reid, KR Rosales, XH Lowman, ...
Journal of translational medicine 13 (1), 210, 2015
Acquired resistance and clonal evolution in melanoma during BRAF inhibitor therapy. Cancer Discov. 2014; 4: 80–93. doi: 10.1158/2159-8290
H Shi, W Hugo, X Kong, A Hong, RC Koya, G Moriceau, T Chodon, R Guo, ...
CD-13-0642.[PMC free article][Abstract][Cross Ref], 0
Exploiting drug addiction mechanisms to select against MAPKi-resistant melanoma
A Hong, G Moriceau, L Sun, S Lomeli, M Piva, R Damoiseaux, SL Holmen, ...
Cancer discovery, 2017
Exploiting drug addiction mechanisms to select against
A Hong, G Moriceau, L Sun, S Lomeli, M Piva, R Damoiseaux, SL Holmen, ...
JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma
B Titz, A Lomova, A Le, W Hugo, X Kong, J Ten Hoeve, M Friedman, H Shi, ...
Cell discovery 2, 16028, 2016
Therapeutic approach of primary bone tumours by bisphosphonates
G Moriceau, B Ory, B Gobin, F Verrecchia, F Gouin, F Blanchard, F Redini, ...
Current Pharmaceutical Design 16 (27), 2981-2987, 2010
Imatinib mesylate exerts anti-proliferative effects on osteosarcoma cells and inhibits the tumour growth in immunocompetent murine models
B Gobin, G Moriceau, B Ory, C Charrier, R Brion, F Blanchard, F Redini, ...
PloS one 9 (3), e90795, 2014
mTOR inhibitors (rapamycin and its derivatives) and nitrogen containing bisphosphonates: bi-functional compounds for the treatment of bone tumours
B Ory, G Moriceau, F Redini, D Heymann
Current medicinal chemistry 14 (13), 1381-1387, 2007
Regulation of osteoprotegerin pro-or anti-tumoral activity by bone tumor microenvironment
F Lamoureux, G Moriceau, G Picarda, J Rousseau, V Trichet, F Rédini
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1805 (1), 17-24, 2010
Farnesyl diphosphate synthase is involved in the resistance to zoledronic acid of osteosarcoma cells
B Ory, G Moriceau, V Trichet, F Blanchard, M Berreur, F Rédini, M Rogers, ...
Journal of cellular and molecular medicine 12 (3), 928-941, 2008
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