Arthur J Michalek
Arthur J Michalek
Associate Professor of Mechanical & Aeronautical Engineering, Clarkson University
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Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair?
JC Iatridis, SB Nicoll, AJ Michalek, BA Walter, MS Gupta
The Spine Journal 13 (3), 243-262, 2013
Complex loading affects intervertebral disc mechanics and biology
BA Walter, CL Korecki, D Purmessur, PJ Roughley, AJ Michalek, ...
Osteoarthritis and cartilage 19 (8), 1011-1018, 2011
Genipin-crosslinked fibrin hydrogels as a potential adhesive to augment intervertebral disc annulus repair
RM Schek, AJ Michalek, JC Iatridis
European cells & materials 21, 373, 2011
Measurement of local strains in intervertebral disc anulus fibrosus tissue under dynamic shear: contributions of matrix fiber orientation and elastin content
AJ Michalek, MR Buckley, LJ Bonassar, I Cohen, JC Iatridis
Journal of biomechanics 42 (14), 2279-2285, 2009
Needle puncture injury of the rat intervertebral disc affects torsional and compressive biomechanics differently
AJ Michalek, KL Funabashi, JC Iatridis
European Spine Journal 19 (12), 2110-2116, 2010
The effects of needle puncture injury on microscale shear strain in the intervertebral disc annulus fibrosus
AJ Michalek, MR Buckley, LJ Bonassar, I Cohen, JC Iatridis
The Spine Journal 10 (12), 1098-1105, 2010
Localized intervertebral disc injury leads to organ level changes in structure, cellularity, and biosynthesis
JC Iatridis, AJ Michalek, D Purmessur, CL Korecki
Cellular and molecular bioengineering 2 (3), 437-447, 2009
Analysis of quantitative magnetic resonance imaging and biomechanical parameters on human discs with different grades of degeneration
J Antoniou, LM Epure, AJ Michalek, MP Grant, JC Iatridis, F Mwale
Journal of Magnetic Resonance Imaging 38 (6), 1402-1414, 2013
Effects of torsion on intervertebral disc gene expression and biomechanics, using a rat tail model
A Barbir, KE Godburn, AJ Michalek, A Lai, RD Monsey, JC Iatridis
Spine 36 (8), 607, 2011
Height and torsional stiffness are most sensitive to annular injury in large animal intervertebral discs
AJ Michalek, JC Iatridis
The Spine Journal 12 (5), 425-432, 2012
Different effects of static versus cyclic compressive loading on rat intervertebral disc height and water loss in vitro
K Masuoka, AJ Michalek, JJ MacLean, IAF Stokes, JC Iatridis
Spine 32 (18), 1974, 2007
Effects of enzymatic digestion on compressive properties of rat intervertebral discs
A Barbir, AJ Michalek, RD Abbott, JC Iatridis
Journal of biomechanics 43 (6), 1067-1073, 2010
Phosphorylation and calcium antagonistically tune myosin-binding protein C’s structure and function
MJ Previs, JY Mun, AJ Michalek, SB Previs, J Gulick, J Robbins, ...
Proceedings of the National Academy of Sciences 113 (12), 3239-3244, 2016
Large residual strains are present in the intervertebral disc annulus fibrosus in the unloaded state
AJ Michalek, MG Gardner-Morse, JC Iatridis
Journal of biomechanics 45 (7), 1227-1231, 2012
Evaluation of quantitative magnetic resonance imaging, biochemical and mechanical properties of trypsin‐treated intervertebral discs under physiological compression loading
F Mwale, CN Demers, AJ Michalek, G Beaudoin, T Goswami, L Beckman, ...
Journal of Magnetic Resonance Imaging: An Official Journal of the …, 2008
Phosphorylation modulates the mechanical stability of the cardiac myosin-binding protein C motif
AJ Michalek, JW Howarth, J Gulick, MJ Previs, J Robbins, PR Rosevear, ...
Biophysical journal 104 (2), 442-452, 2013
A numerical study to determine pericellular matrix modulus and evaluate its effects on the micromechanical environment of chondrocytes
AJ Michalek, JC Iatridis
Journal of biomechanics 40 (6), 1405-1409, 2007
Penetrating annulus fibrosus injuries affect dynamic compressive behaviors of the intervertebral disc via altered fluid flow: an analytical interpretation
AJ Michalek, JC Iatridis
Journal of biomechanical engineering 133 (8), 2011
Molecular modulation of actomyosin function by cardiac myosin-binding protein C
MJ Previs, AJ Michalek, DM Warshaw
Pflügers Archiv-European Journal of Physiology 466 (3), 439-444, 2014
Residual strains in the intervertebral disc annulus fibrosus suggest complex tissue remodeling in response to in-vivo loading
SE Duclos, AJ Michalek
Journal of the mechanical behavior of biomedical materials 68, 232-238, 2017
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