Philip C. Biggin
TitleCited byYear
A hydrophobic gating mechanism for nanopores
O Beckstein, PC Biggin, MSP Sansom
The Journal of Physical Chemistry B 105 (51), 12902-12905, 2001
Structure and orientation of the mammalian antibacterial peptide cecropin P1 within phospholipid membranes
E Gazit, IR Miller, PC Biggin, MSP Sansom, Y Shai
Journal of molecular biology 258 (5), 860-870, 1996
Simulation approaches to ion channel structure-function relationships.
DP Tieleman, PC Biggin, GR Smith, MS Sansom
Quaterley Reviews in Biophysics 34 (4), 473-561, 2001
Potassium channels: structures, models, simulations
MSP Sansom, IH Shrivastava, JN Bright, J Tate, CE Capener, PC Biggin
Biochimica et Biophysica Acta (BBA)-Biomembranes 1565 (2), 294-307, 2002
Insect GABA receptors: splicing, editing, and targeting by antiparasitics and insecticides
SD Buckingham, PC Biggin, BM Sattelle, LA Brown, DB Sattelle
Molecular pharmacology 68 (4), 942-951, 2005
The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy
P Luik, C Chew, J Aittoniemi, J Chang, P Wentworth, RA Dwek, PC Biggin, ...
Proceedings of the National Academy of Sciences 106 (31), 12712-12716, 2009
K+ versus Na+ ions in a K channel selectivity filter: a simulation study
IH Shrivastava, DP Tieleman, PC Biggin, MSP Sansom
Biophysical journal 83 (2), 633-645, 2002
Biophysics: water at the nanoscale
MSP Sansom, PC Biggin
Nature 414 (6860), 156, 2001
Edit, cut and paste in the nicotinic acetylcholine receptor gene family of Drosophila melanogaster
DB Sattelle, AK Jones, BM Sattelle, K Matsuda, R Reenan, PC Biggin
Bioessays 27 (4), 366-376, 2005
Simulation studies of the interaction of antimicrobial peptides and lipid bilayers
P La Rocca, PC Biggin, DP Tieleman, MSP Sansom
Biochimica et Biophysica Acta (BBA)-Biomembranes 1462 (1-2), 185-200, 1999
Interactions of α-helices with lipid bilayers: a review of simulation studies
PC Biggin, MSP Sansom
Biophysical chemistry 76 (3), 161-183, 1999
Ion channel gating: insights via molecular simulations
O Beckstein, PC Biggin, P Bond, JN Bright, C Domene, A Grottesi, ...
FEBS letters 555 (1), 85-90, 2003
Rapid and accurate prediction and scoring of water molecules in protein binding sites
GA Ross, GM Morris, PC Biggin
PloS one 7 (3), e32036, 2012
Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump
J Marcoux, SC Wang, A Politis, E Reading, J Ma, PC Biggin, M Zhou, ...
Proceedings of the National Academy of Sciences 110 (24), 9704-9709, 2013
Towards understanding promiscuity in multidrug efflux pumps
K Wong, J Ma, A Rothnie, PC Biggin, ID Kerr
Trends in biochemical sciences 39 (1), 8-16, 2014
Predictive low-glucose insulin suspension reduces duration of nocturnal hypoglycemia in children without increasing ketosis
BA Buckingham, D Raghinaru, F Cameron, BW Bequette, HP Chase, ...
Diabetes Care 38 (7), 1197-1204, 2015
Additional acetylcholine (ACh) binding site at α4/α4 interface of (α4β2) 2α4 nicotinic receptor influences agonist sensitivity
S Mazzaferro, N Benallegue, A Carbone, F Gasparri, R Vijayan, ...
Journal of Biological Chemistry 286 (35), 31043-31054, 2011
Molecular dynamics simulations of the ligand-binding domain of the ionotropic glutamate receptor GluR2
Y Arinaminpathy, MSP Sansom, PC Biggin
Biophysical journal 82 (2), 676-683, 2002
The dielectric properties of water within model transbilayer pores
MS Sansom, GR Smith, C Adcock, PC Biggin
Biophysical journal 73 (5), 2404-2415, 1997
Accurate calculation of the absolute free energy of binding for drug molecules
M Aldeghi, A Heifetz, MJ Bodkin, S Knapp, PC Biggin
Chemical science 7 (1), 207-218, 2016
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Articles 1–20