| Receptor for advanced glycation end products (RAGE)-mediated neurite outgrowth and activation of NF-κB require the cytoplasmic domain of the receptor but different downstream … HJ Huttunen, C Fages, H Rauvala Journal of Biological Chemistry 274 (28), 19919-19924, 1999 | 805 | 1999 |
| Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation HJ Huttunen, J Kuja-Panula, G Sorci, AL Agneletti, R Donato, H Rauvala Journal of Biological Chemistry 275 (51), 40096-40105, 2000 | 787 | 2000 |
| Receptor for advanced glycation end products-binding COOH-terminal motif of amphoterin inhibits invasive migration and metastasis HJ Huttunen, C Fages, J Kuja-Panula, AJ Ridley, H Rauvala Cancer research 62 (16), 4805-4811, 2002 | 422 | 2002 |
| The ACAT inhibitor CP-113,818 markedly reduces amyloid pathology in a mouse model of Alzheimer's disease B Hutter-Paier, HJ Huttunen, L Puglielli, CB Eckman, DY Kim, ... Neuron 44 (2), 227-238, 2004 | 330 | 2004 |
| Mechanisms of secretion and spreading of pathological tau protein CA Brunello, M Merezhko, RL Uronen, HJ Huttunen Cellular and Molecular Life Sciences 77, 1721-1744, 2020 | 226 | 2020 |
| Amphoterin as an extracellular regulator of cell motility: from discovery to disease HJ Huttunen, H Rauvala Journal of internal medicine 255 (3), 351-366, 2004 | 216 | 2004 |
| Regulation of cell migration by amphoterin C Fages, R Nolo, HJ Huttunen, EL Eskelinen, H Rauvala Journal of cell science 113 (4), 611-620, 2000 | 206 | 2000 |
| Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation HJ Huttunen, J Kuja-Panula, H Rauvala Journal of Biological Chemistry 277 (41), 38635-38646, 2002 | 197 | 2002 |
| N‐Glycans on the receptor for advanced glycation end products influence amphoterin binding and neurite outgrowth G Srikrishna, HJ Huttunen, L Johansson, B Weigle, Y Yamaguchi, ... Journal of neurochemistry 80 (6), 998-1008, 2002 | 195 | 2002 |
| Heparin-binding proteins HB-GAM (pleiotrophin) and amphoterin in the regulation of cell motility H Rauvala, HJ Huttunen, C Fages, M Kaksonen, T Kinnunen, S Imai, ... Matrix Biology 19 (5), 377-387, 2000 | 195 | 2000 |
| PCSK9 regulates neuronal apoptosis by adjusting ApoER2 levels and signaling K Kysenius, P Muggalla, K Mätlik, U Arumäe, HJ Huttunen Cellular and molecular life sciences 69, 1903-1916, 2012 | 143 | 2012 |
| Secretion of tau via an unconventional non-vesicular mechanism M Merezhko, CA Brunello, X Yan, H Vihinen, E Jokitalo, RL Uronen, ... Cell reports 25 (8), 2027-2035. e4, 2018 | 139 | 2018 |
| S100B Interaction With the Receptor for Advanced Glycation End Products (RAGE) A Novel Receptor-Mediated Mechanism for Myocyte Apoptosis Postinfarction JN Tsoporis, S Izhar, H Leong-Poi, JF Desjardins, HJ Huttunen, TG Parker Circulation Research 106 (1), 93-101, 2010 | 134 | 2010 |
| Microglial activation induces cell death, inhibits neurite outgrowth and causes neurite retraction of differentiated neuroblastoma cells G Münch, J Gasic-Milenkovic, S Dukic-Stefanovic, B Kuhla, K Heinrich, ... Experimental brain research 150, 1-8, 2003 | 110 | 2003 |
| GDNF and Parkinson’s disease: where next? A summary from a recent workshop RA Barker, A Björklund, DM Gash, A Whone, A Van Laar, JH Kordower, ... Journal of Parkinson's disease 10 (3), 875-891, 2020 | 95 | 2020 |
| HtrA2 regulates β-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation HJ Huttunen, SY Guénette, C Peach, C Greco, W Xia, DY Kim, C Barren, ... Journal of biological chemistry 282 (38), 28285-28295, 2007 | 88 | 2007 |
| CDNF protein therapy in Parkinson’s disease HJ Huttunen, M Saarma Cell Transplantation 28 (4), 349-366, 2019 | 74 | 2019 |
| Prolyl oligopeptidase enhances α-synuclein dimerization via direct protein-protein interaction MH Savolainen, X Yan, TT Myöhänen, HJ Huttunen Journal of Biological Chemistry 290 (8), 5117-5126, 2015 | 74 | 2015 |
| Internalized Tau sensitizes cells to stress by promoting formation and stability of stress granules CA Brunello, X Yan, HJ Huttunen Scientific Reports 6 (1), 30498, 2016 | 72 | 2016 |
| Thyroxin regulates BDNF expression to promote survival of injured neurons A Shulga, A Blaesse, K Kysenius, HJ Huttunen, K Tanhuanpää, ... Molecular and Cellular Neuroscience 42 (4), 408-418, 2009 | 70 | 2009 |
Ville JokinenAalto University, Department of Chemistry and Materials ScienceVerified email at aalto.fi
