Christopher Dobson
Christopher Dobson
Verified email at cam.ac.uk - Homepage
TitleCited byYear
Protein misfolding, functional amyloid, and human disease
F Chiti, CM Dobson
Annu. Rev. Biochem. 75, 333-366, 2006
52342006
Protein folding and misfolding
CM Dobson
Nature 426 (6968), 884, 2003
40932003
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
M Bucciantini, E Giannoni, F Chiti, F Baroni, L Formigli, J Zurdo, N Taddei, ...
nature 416 (6880), 507, 2002
24112002
Protein misfolding, evolution and disease
CM Dobson
Trends in biochemical sciences 24 (9), 329-332, 1999
20161999
Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution
M Stefani, CM Dobson
Journal of molecular medicine 81 (11), 678-699, 2003
15742003
Designing conditions for in vitro formation of amyloid protofilaments and fibrils
F Chiti, P Webster, N Taddei, A Clark, M Stefani, G Ramponi, CM Dobson
Proceedings of the National Academy of Sciences 96 (7), 3590-3594, 1999
11631999
Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis
DR Booth, M Sunde, V Bellotti, CV Robinson, WL Hutchinson, PE Fraser, ...
Nature 385 (6619), 787, 1997
11271997
Rationalization of the effects of mutations on peptide andprotein aggregation rates
F Chiti, M Stefani, N Taddei, G Ramponi, CM Dobson
Nature 424 (6950), 805, 2003
10312003
The amyloid state and its association with protein misfolding diseases
TPJ Knowles, M Vendruscolo, CM Dobson
Nature reviews Molecular cell biology 15 (6), 384, 2014
10022014
The structural basis of protein folding and its links with human disease
CM Dobson
Philosophical Transactions of the Royal Society of London. Series B …, 2001
9552001
Protein folding: a perspective from theory and experiment
CM Dobson, A Šali, M Karplus
Angewandte Chemie International Edition 37 (7), 868-893, 1998
9211998
Principles of protein folding, misfolding and aggregation
CM Dobson
Seminars in cell & developmental biology 15 (1), 3-16, 2004
9002004
Amyloid fibrils from muscle myoglobin
M Fändrich, MA Fletcher, CM Dobson
Nature 410 (6825), 165, 2001
8152001
Chemical space and biology
CM Dobson
Nature 432 (7019), 824, 2004
8142004
The protofilament structure of insulin amyloid fibrils
JL Jiménez, EJ Nettleton, M Bouchard, CV Robinson, CM Dobson, ...
Proceedings of the National Academy of Sciences 99 (14), 9196-9201, 2002
8112002
Hydrodynamic radii of native and denatured proteins measured by pulse field gradient NMR techniques
DK Wilkins, SB Grimshaw, V Receveur, CM Dobson, JA Jones, LJ Smith
Biochemistry 38 (50), 16424-16431, 1999
8061999
The folding of hen lysozyme involves partially structured intermediates and multiple pathways
SE Radford, CM Dobson, PA Evans
Nature 358 (6384), 302, 1992
8011992
Amyloid fibril formation by an SH3 domain
JI Guijarro, M Sunde, JA Jones, ID Campbell, CM Dobson
Proceedings of the National Academy of Sciences 95 (8), 4224-4228, 1998
7281998
An analytical solution to the kinetics of breakable filament assembly
TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, ...
Science 326 (5959), 1533-1537, 2009
6942009
Amyloid formation by globular proteins under native conditions
F Chiti, CM Dobson
Nature chemical biology 5 (1), 15, 2009
6942009
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