Induction of a central memory and stem cell memory phenotype in functionally active CD4+ and CD8+ CAR T cells produced in an automated good manufacturing practice … F Blaeschke, D Stenger, T Kaeuferle, S Willier, R Lotfi, AD Kaiser, ... Cancer Immunology, Immunotherapy 67, 1053-1066, 2018 | 148 | 2018 |
Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR D Stenger, TA Stief, T Kaeuferle, S Willier, F Rataj, K Schober, B Vick, ... Blood, The Journal of the American Society of Hematology 136 (12), 1407-1418, 2020 | 110 | 2020 |
DNA methylation mediated control of gene expression is critical for development of crown gall tumors J Gohlke, CJ Scholz, S Kneitz, D Weber, J Fuchs, R Hedrich, R Deeken PLoS genetics 9 (2), e1003267, 2013 | 76 | 2013 |
CLEC12A and CD33 coexpression as a preferential target for pediatric AML combinatorial immunotherapy S Willier, P Rothämel, M Hastreiter, J Wilhelm, D Stenger, F Blaeschke, ... Blood, The Journal of the American Society of Hematology 137 (8), 1037-1049, 2021 | 53 | 2021 |
Leukemia-induced dysfunctional TIM-3+CD4+ bone marrow T cells increase risk of relapse in pediatric B-precursor ALL patients F Blaeschke, S Willier, D Stenger, M Lepenies, MA Horstmann, ... Leukemia 34 (10), 2607-2620, 2020 | 35 | 2020 |
Augmenting anti-CD19 and anti-CD22 CAR T-cell function using PD-1-CD28 checkpoint fusion proteins F Blaeschke, D Stenger, A Apfelbeck, BL Cadilha, MR Benmebarek, ... Blood Cancer Journal 11 (6), 108, 2021 | 19 | 2021 |
Design and evaluation of TIM-3-CD28 checkpoint fusion proteins to improve anti-CD19 CAR T-cell function F Blaeschke, E Ortner, D Stenger, J Mahdawi, A Apfelbeck, N Habjan, ... Frontiers in Immunology 13, 845499, 2022 | 12 | 2022 |
Leukemia escape in immune desert: intraocular relapse of pediatric pro-B-ALL during systemic control by CD19-CAR T cells S Willier, J Raedler, F Blaeschke, D Stenger, MP Escudero, F Jurgeleit, ... Journal for Immunotherapy of Cancer 8 (2), 2020 | 9 | 2020 |
Genome‐wide off‐target analyses of CRISPR/Cas9‐mediated T‐cell receptor engineering in primary human T cells T Kaeuferle, TA Stief, S Canzar, NN Kutlu, S Willier, D Stenger, ... Clinical & Translational Immunology 11 (1), e1372, 2022 | 6 | 2022 |
Endogenous TCR Promotes D Stenger, TA Stief, T Kaeuferle, S Willier, F Rataj, K Schober Vivo, 2020 | 5 | 2020 |
CD19-specific CAR T cells with a central memory and stem memory phenotype-automated generation in a closed, gmp-compatible system from peripheral blood of pediatric patients … F Blaeschke, D Stenger, T Kaeuferle, S Willier, R Lotfi, A Kaiser, ... BONE MARROW TRANSPLANTATION 52, S27-S28, 2017 | 2 | 2017 |
Bone marrow T cells are driven into exhaustion by acute leukemia in pediatric patients based on protein and transcriptome analysis S Willier, P Rothaemel, J Wilhelm, D Stenger, T Kaeuferle, I Schmid, ... Blood 132, 3722, 2018 | 1 | 2018 |
CD28 CAR T Cells for the Treatment of T Cell Malignancies S Willier, J Färber, T Ispyrlidou, D Stenger, SLM Nikolaides, PF Ernst, ... Blood 142, 3448, 2023 | | 2023 |
Genome2̆010wide off\0̆10target analyses of CRISPR/Cas9\u1̆0mediated T\u20̆cell receptor engineering in primary human T cells T Kaeuferle, TA Stief, S Canzar, NN Kutlu, S Willier, D Stenger, ... Clinical & Translational Immunology 11 (1), 2022 | | 2022 |
Breaking PD-11-mediated Resistance in anti-CD19 and anti-CD22 Car T Cells with PD-1/CD28 Fusion Receptors F Blaeschke, A Apfelbeck, D Stenger, J Mahdawi, M Lepenies, F Rataj, ... BONE MARROW TRANSPLANTATION 55 (SUPPL 1), 258-259, 2020 | | 2020 |
TIM-3-mediated immunosurveillance of acute lymphoblastic leukemia by CD4+ bone marrow T cells: Implications for relapse and graft-versus-leukemia effects F Blaeschke, S Willier, D Stenger, M Lepenies, MA Horstmann, ... BONE MARROW TRANSPLANTATION 54, 25-25, 2019 | | 2019 |
Bone marrow T-cells are tumor-infiltrating T-cells in pediatric patients with acute leukemia and their phenotype reflects immune evasion of leukemic blasts SM Willier, P Rothaemel, J Wilhelm, D Stenger, T Kaeuferle, I Schmid, ... CANCER IMMUNOLOGY RESEARCH 7 (2), 2019 | | 2019 |
Anti-CD19 CAR T-cells with a CRISPR/Cas9-mediated T-cell receptor knockout show high functionality in the absence of alloreactivity in vitro D Stenger, T Stief, T Kaeuferle, SM Willier, F Rataj, K Schober, R Lotfi, ... CANCER IMMUNOLOGY RESEARCH 7 (2), 2019 | | 2019 |
Abstract A043: Anti-CD19 CAR T-cells with a CRISPR/Cas9-mediated T-cell receptor knockout show high functionality in the absence of alloreactivity in vitro D Stenger, T Stief, T Käuferle, SM Willier, F Rataj, K Schober, R Lotfi, ... Cancer Immunology Research 7 (2_Supplement), A043-A043, 2019 | | 2019 |
Abstract A224: Bone marrow T-cells are tumor-infiltrating T-cells in pediatric patients with acute leukemia and their phenotype reflects immune evasion of leukemic blasts SM Willier, P Rothaemel, J Wilhelm, D Stenger, T Käuferle, I Schmid, ... Cancer Immunology Research 7 (2_Supplement), A224-A224, 2019 | | 2019 |