| Safety and efficacy of drisapersen for the treatment of Duchenne muscular dystrophy (DEMAND II): an exploratory, randomised, placebo-controlled phase 2 study T Voit, H Topaloglu, V Straub, F Muntoni, N Deconinck, G Campion, ... The Lancet Neurology 13 (10), 987-996, 2014 | 383 | 2014 |
| Characterization of rhodamine-123 as a tracer dye for use in in vitro drug transport assays S Forster, AE Thumser, SR Hood, N Plant PloS one 7 (3), e33253, 2012 | 204 | 2012 |
| A Randomized, Double‐Blind, Placebo‐Controlled, First‐Time‐in‐Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of … K Han, J Cremer, R Elston, S Oliver, S Baptiste‐Brown, S Chen, ... Clinical Pharmacology in Drug Development 8 (6), 790-801, 2019 | 48 | 2019 |
| The dynamics of compound, transcript, and protein effects after treatment with 2OMePS antisense oligonucleotides in mdx mice IEC Verhaart, L Van Vliet-van Den Dool, JA Sipkens, SJ De Kimpe, ... Molecular Therapy-Nucleic Acids 3, 2014 | 34 | 2014 |
| Impact of transcription factor profile and chromatin conformation on human hepatocyte CYP3A gene expression A Phillips, SR Hood, GG Gibson, NJ Plant Drug Metabolism and Disposition 33 (2), 233-242, 2005 | 29 | 2005 |
| Optimization of stress response through the nuclear receptor-mediated cortisol signalling network A Kolodkin, N Sahin, A Phillips, SR Hood, FJ Bruggeman, HV Westerhoff, ... Nature Communications 4 (1), 1792, 2013 | 28 | 2013 |
| Simultaneous label-free autofluorescence and multi-harmonic imaging reveals in vivo structural and metabolic changes in murine skin JH Lee, JJ Rico-Jimenez, C Zhang, A Alex, EJ Chaney, R Barkalifa, ... Biomedical optics express 10 (10), 5431-5444, 2019 | 27 | 2019 |
| Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling CC Horgan, A Nagelkerke, TE Whittaker, V Nele, L Massi, U Kauscher, ... Journal of Materials Chemistry B 8 (20), 4447-4459, 2020 | 26 | 2020 |
| Highly purified extracellular vesicles from human cardiomyocytes demonstrate preferential uptake by human endothelial cells L Zwi-Dantsis, CW Winter, U Kauscher, A Ferrini, B Wang, TE Whittaker, ... Nanoscale 12 (38), 19844-19854, 2020 | 23 | 2020 |
| Coordinate induction of hepatic fatty acyl-CoA oxidase and P4504A1 in rat after activation of the peroxisome proliferator-activated receptor (PPAR) by sulphur-substituted fatty … A Demoz, H Vaagenes, N Aarsaether, E Hvattum, J Skorve, M Gottlicher, ... Xenobiotica 24 (9), 943-956, 1994 | 16 | 1994 |
| Navigating CYP1A Induction and Arylhydrocarbon Receptor Agonism in Drug Discovery. A Case History with S1P1 Agonists SJ Taylor, EH Demont, J Gray, N Deeks, A Patel, D Nguyen, M Taylor, ... Journal of Medicinal Chemistry 58 (20), 8236-8256, 2015 | 15 | 2015 |
| Longitudinal monitoring of cell metabolism in biopharmaceutical production using label‐free fluorescence lifetime imaging microscopy SM Sternisha, P Mukherjee, A Alex, EJ Chaney, R Barkalifa, B Wan, ... Biotechnology Journal 16 (7), 2000629, 2021 | 13 | 2021 |
| Differential uptake of antisense oligonucleotides in mouse hepatocytes and macrophages revealed by simultaneous two-photon excited fluorescence and coherent Raman imaging P Mukherjee, E Aksamitiene, A Alex, J Shi, K Bera, C Zhang, DR Spillman, ... nucleic acid therapeutics 32 (3), 163-176, 2022 | 11 | 2022 |
| Preclinical and Phase 1 Assessment of Antisense Oligonucleotide Bepirovirsen in Hepatitis B Virus–Transgenic Mice and Healthy Human Volunteers: Support for Clinical Dose … K Han, D Theodore, G McMullen, E Swayze, M McCaleb, G Billioud, ... Clinical Pharmacology in Drug Development 11 (10), 1191-1202, 2022 | 8 | 2022 |
| Quantification of drugs in brain and liver mimetic tissue models Using Raman spectroscopy N Woodhouse, J Majer, P Marshall, S Hood, I Notingher Applied Spectroscopy 77 (3), 246-260, 2023 | 7 | 2023 |
| Characterization of Rhodamine-123 as a Tracer Dye for Use in S Forster, AE Thumser, SR Hood, N Plant vitro, 2012 | 7 | 2012 |
| Will nanomedicine deliver on its promise of changing therapeutics or remain an interesting and important research tool in cell biology and physiology? R Kirsh, S Hood, C Brook, A Gilmartin, P Dell'orco, T Meek International Journal of Pharmaceutics 454 (1), 530-531, 2013 | 5 | 2013 |
| CYP3A and nuclear receptor messenger RNA expression in liver and HuH7 cells AL Phillips, SR Hood, GG Gibson, NJ Plant Drug Metabolism Reviews 35, 83-83, 2003 | 5 | 2003 |
| Evaluating virtual staining for high-throughput screening S Tonks, CY Hsu, S Hood, R Musso, C Hopely, S Titus, A Krull, M Doan, ... 2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI), 1-5, 2023 | 4 | 2023 |
| Comparison of Pharmacokinetics of the GalNAc-Conjugated Antisense Oligonucleotide GSK3389404 in Participants with Chronic Hepatitis B Infection across the Asia-Pacific Region K Han, H Ito, R Elston, J Cremer, S Hood, M Paff, D Theodore Antimicrobial Agents and Chemotherapy 67 (1), e00900-22, 2023 | 3 | 2023 |
