Steve Hood PHD FRSB
Steve Hood PHD FRSB
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Safety and efficacy of drisapersen for the treatment of Duchenne muscular dystrophy (DEMAND II): an exploratory, randomised, placebo-controlled phase 2 study
T Voit, H Topaloglu, V Straub, F Muntoni, N Deconinck, G Campion, ...
The Lancet Neurology 13 (10), 987-996, 2014
Characterization of rhodamine-123 as a tracer dye for use in in vitro drug transport assays
S Forster, AE Thumser, SR Hood, N Plant
PloS one 7 (3), e33253, 2012
A Randomized, Double‐Blind, Placebo‐Controlled, First‐Time‐in‐Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of …
K Han, J Cremer, R Elston, S Oliver, S Baptiste‐Brown, S Chen, ...
Clinical Pharmacology in Drug Development 8 (6), 790-801, 2019
The dynamics of compound, transcript, and protein effects after treatment with 2OMePS antisense oligonucleotides in mdx mice
IEC Verhaart, L Van Vliet-van Den Dool, JA Sipkens, SJ De Kimpe, ...
Molecular Therapy-Nucleic Acids 3, 2014
Impact of transcription factor profile and chromatin conformation on human hepatocyte CYP3A gene expression
A Phillips, SR Hood, GG Gibson, NJ Plant
Drug Metabolism and Disposition 33 (2), 233-242, 2005
Optimization of stress response through the nuclear receptor-mediated cortisol signalling network
A Kolodkin, N Sahin, A Phillips, SR Hood, FJ Bruggeman, HV Westerhoff, ...
Nature Communications 4 (1), 1792, 2013
Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling
CC Horgan, A Nagelkerke, TE Whittaker, V Nele, L Massi, U Kauscher, ...
Journal of Materials Chemistry B 8 (20), 4447-4459, 2020
Simultaneous label-free autofluorescence and multi-harmonic imaging reveals in vivo structural and metabolic changes in murine skin
JH Lee, JJ Rico-Jimenez, C Zhang, A Alex, EJ Chaney, R Barkalifa, ...
Biomedical optics express 10 (10), 5431-5444, 2019
Highly purified extracellular vesicles from human cardiomyocytes demonstrate preferential uptake by human endothelial cells
L Zwi-Dantsis, CW Winter, U Kauscher, A Ferrini, B Wang, TE Whittaker, ...
Nanoscale 12 (38), 19844-19854, 2020
Coordinate induction of hepatic fatty acyl-CoA oxidase and P4504A1 in rat after activation of the peroxisome proliferator-activated receptor (PPAR) by sulphur-substituted fatty …
A Demoz, H Vaagenes, N Aarsaether, E Hvattum, J Skorve, M Gottlicher, ...
Xenobiotica 24 (9), 943-956, 1994
Navigating CYP1A Induction and Arylhydrocarbon Receptor Agonism in Drug Discovery. A Case History with S1P1 Agonists
SJ Taylor, EH Demont, J Gray, N Deeks, A Patel, D Nguyen, M Taylor, ...
Journal of Medicinal Chemistry 58 (20), 8236-8256, 2015
Longitudinal monitoring of cell metabolism in biopharmaceutical production using label‐free fluorescence lifetime imaging microscopy
SM Sternisha, P Mukherjee, A Alex, EJ Chaney, R Barkalifa, B Wan, ...
Biotechnology Journal 16 (7), 2000629, 2021
Differential uptake of antisense oligonucleotides in mouse hepatocytes and macrophages revealed by simultaneous two-photon excited fluorescence and coherent Raman imaging
P Mukherjee, E Aksamitiene, A Alex, J Shi, K Bera, C Zhang, DR Spillman, ...
nucleic acid therapeutics 32 (3), 163-176, 2022
Quantification of drugs in brain and liver mimetic tissue models Using Raman spectroscopy
N Woodhouse, J Majer, P Marshall, S Hood, I Notingher
Applied Spectroscopy 77 (3), 246-260, 2023
Preclinical and Phase 1 Assessment of Antisense Oligonucleotide Bepirovirsen in Hepatitis B Virus–Transgenic Mice and Healthy Human Volunteers: Support for Clinical Dose …
K Han, D Theodore, G McMullen, E Swayze, M McCaleb, G Billioud, ...
Clinical Pharmacology in Drug Development 11 (10), 1191-1202, 2022
Characterization of Rhodamine-123 as a Tracer Dye for Use in
S Forster, AE Thumser, SR Hood, N Plant
vitro, 2012
Will nanomedicine deliver on its promise of changing therapeutics or remain an interesting and important research tool in cell biology and physiology?
R Kirsh, S Hood, C Brook, A Gilmartin, P Dell'orco, T Meek
International Journal of Pharmaceutics 454 (1), 530-531, 2013
CYP3A and nuclear receptor messenger RNA expression in liver and HuH7 cells
AL Phillips, SR Hood, GG Gibson, NJ Plant
Drug Metabolism Reviews 35, 83-83, 2003
Evaluating virtual staining for high-throughput screening
S Tonks, CY Hsu, S Hood, R Musso, C Hopely, S Titus, A Krull, M Doan, ...
2023 IEEE 20th International Symposium on Biomedical Imaging (ISBI), 1-5, 2023
Comparison of Pharmacokinetics of the GalNAc-Conjugated Antisense Oligonucleotide GSK3389404 in Participants with Chronic Hepatitis B Infection across the Asia-Pacific Region
K Han, H Ito, R Elston, J Cremer, S Hood, M Paff, D Theodore
Antimicrobial Agents and Chemotherapy 67 (1), e00900-22, 2023
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