| Multi-step organic synthesis using solid-supported reagents and scavengers: a new paradigm in chemical library generation SV Ley, IR Baxendale, RN Bream, PS Jackson, AG Leach, ... Journal of the Chemical Society, Perkin Transactions 1, 3815-4195, 2000 | 958 | 2000 |
| An overview of the synthetic routes to the best selling drugs containing 6-membered heterocycles M Baumann, IR Baxendale Beilstein journal of organic chemistry 9 (1), 2265-2319, 2013 | 793 | 2013 |
| An overview of the key routes to the best selling 5-membered ring heterocyclic pharmaceuticals M Baumann, IR Baxendale, SV Ley, N Nikbin Beilstein Journal of Organic Chemistry 7 (1), 442-495, 2011 | 596 | 2011 |
| The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule BCS Cross, PJ Bond, PG Sadowski, BK Jha, J Zak, JM Goodman, ... Proceedings of the National Academy of Sciences 109 (15), E869-E878, 2012 | 577 | 2012 |
| The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry M Baumann, IR Baxendale Beilstein journal of organic chemistry 11 (1), 1194-1219, 2015 | 388 | 2015 |
| The use of gases in flow synthesis CJ Mallia, IR Baxendale Organic Process Research & Development 20 (2), 327-360, 2016 | 347 | 2016 |
| New tools and concepts for modern organic synthesis SV Ley, IR Baxendale Nature Reviews Drug Discovery 1 (8), 573-586, 2002 | 347 | 2002 |
| Flow ozonolysis using a semipermeable Teflon AF-2400 membrane to effect gas− liquid contact M O’Brien, IR Baxendale, SV Ley Organic letters 12 (7), 1596-1598, 2010 | 338 | 2010 |
| Microwave‐assisted Suzuki coupling reactions with an encapsulated palladium catalyst for batch and continuous‐flow transformations IR Baxendale, CM Griffiths‐Jones, SV Ley, GK Tranmer Chemistry–A European Journal 12 (16), 4407-4416, 2006 | 306 | 2006 |
| ReactIR flow cell: a new analytical tool for continuous flow chemical processing CF Carter, H Lange, SV Ley, IR Baxendale, B Wittkamp, JG Goode, ... Organic Process Research & Development 14 (2), 393-404, 2010 | 297 | 2010 |
| The integration of flow reactors into synthetic organic chemistry IR Baxendale Journal of Chemical Technology & Biotechnology 88 (4), 519-552, 2013 | 295 | 2013 |
| Multistep synthesis using modular flow reactors: Bestmann–Ohira reagent for the formation of alkynes and triazoles IR Baxendale, SV Ley, AC Mansfield, CD Smith Angewandte Chemie 121 (22), 4077-4081, 2009 | 263 | 2009 |
| The continuous‐flow synthesis of carboxylic acids using CO2 in a tube‐in‐tube gas permeable membrane reactor A Polyzos, M O'Brien, TP Petersen, IR Baxendale, SV Ley Angewandte Chemie-International Edition 50 (5), 1190, 2011 | 260 | 2011 |
| A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly IR Baxendale, J Deeley, CM Griffiths-Jones, SV Ley, S Saaby, ... Chemical communications, 2566-2568, 2006 | 242 | 2006 |
| Hydrogenation in flow: Homogeneous and heterogeneous catalysis using Teflon AF-2400 to effect gas–liquid contact at elevated pressure M O'Brien, N Taylor, A Polyzos, IR Baxendale, SV Ley Chemical Science 2 (7), 1250-1257, 2011 | 237 | 2011 |
| KMnO4-Mediated Oxidation as a Continuous Flow Process J Sedelmeier, SV Ley, IR Baxendale, M Baumann Organic letters 12 (16), 3618-3621, 2010 | 229 | 2010 |
| A flow-based synthesis of Imatinib: the API of Gleevec MD Hopkin, IR Baxendale, SV Ley Chemical communications 46 (14), 2450-2452, 2010 | 218 | 2010 |
| Achieving continuous manufacturing: Technologies and approaches for synthesis, workup, and isolation of drug substance. May 20–21, 2014 Continuous Manufacturing Symposium IR Baxendale, RD Braatz, BK Hodnett, KF Jensen, MD Johnson, ... Journal of pharmaceutical sciences 104 (3), 781-791, 2015 | 196 | 2015 |
| Total syntheses of natural products containing spirocarbocycles LK Smith, IR Baxendale Organic & Biomolecular Chemistry 13 (39), 9907-9933, 2015 | 192 | 2015 |
| Total synthesis of the amaryllidaceae alkaloid (+)‐plicamine and its unnatural enantiomer by using solid‐supported reagents and scavengers in a multistep sequence of reactions IR Baxendale, SV Ley, C Piutti Angewandte Chemie 114 (12), 2298-2301, 2002 | 186 | 2002 |
Christopher SmithUniversity of ReadingVerified email at reading.ac.uk
