Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia C Blauwendraat, X Reed, L Krohn, K Heilbron, S Bandres-Ciga, M Tan, ... Brain 143 (1), 234-248, 2020 | 180 | 2020 |
Genetic analysis of amyotrophic lateral sclerosis identifies contributing pathways and cell types S Saez-Atienzar, S Bandres-Ciga, RG Langston, JJ Kim, SW Choi, ... Science advances 7 (3), eabd9036, 2021 | 66 | 2021 |
Hexokinases link DJ-1 to the PINK1/parkin pathway DN Hauser, A Mamais, MM Conti, CT Primiani, R Kumaran, AA Dillman, ... Molecular neurodegeneration 12, 1-17, 2017 | 53 | 2017 |
Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia A Mamais, JH Kluss, L Bonet-Ponce, N Landeck, RG Langston, N Smith, ... PLoS biology 19 (12), e3001480, 2021 | 51 | 2021 |
Comparisons of interfacial Phe, Tyr, and Trp residues as determinants of orientation and dynamics for GWALP transmembrane peptides KA Sparks, NJ Gleason, R Gist, R Langston, DV Greathouse, RE Koeppe Biochemistry 53 (22), 3637-3645, 2014 | 50 | 2014 |
LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies M Emmenegger, E De Cecco, M Hruska‐Plochan, T Eninger, ... EMBO molecular medicine 13 (9), e14745, 2021 | 49 | 2021 |
Association of a common genetic variant with Parkinson’s disease is mediated by microglia RG Langston, A Beilina, X Reed, A Kaganovich, AB Singleton, ... Science Translational Medicine 14 (655), eabp8869, 2022 | 47 | 2022 |
The G2385R risk factor for Parkinson's disease enhances CHIP-dependent intracellular degradation of LRRK2 IN Rudenko, A Kaganovich, RG Langston, A Beilina, K Ndukwe, ... Biochemical Journal 474 (9), 1547-1558, 2017 | 40 | 2017 |
The function of orthologues of the human Parkinson's disease gene LRRK2 across species: implications for disease modelling in preclinical research RG Langston, IN Rudenko, MR Cookson Biochemical Journal 473 (3), 221-232, 2016 | 34 | 2016 |
Heparin-binding peptide as a novel affinity tag for purification of recombinant proteins J Morris, S Jayanthi, R Langston, A Daily, A Kight, DS McNabb, R Henry, ... Protein expression and purification 126, 93-103, 2016 | 28 | 2016 |
The Polg mutator phenotype does not cause dopaminergic neurodegeneration in DJ-1-deficient mice DN Hauser, CT Primiani, RG Langston, R Kumaran, MR Cookson Eneuro 2 (1), 2015 | 20 | 2015 |
Coding and Noncoding Variation in LRRK2 and Parkinson's Disease Risk J Lake, X Reed, RG Langston, MA Nalls, Z Gan‐Or, MR Cookson, ... Movement disorders 37 (1), 95-105, 2022 | 19 | 2022 |
Characteristics and career outcomes of Neurosurgery Research and Education Foundation research fellowship recipients TA Wilson, RG Langston, KH Wong, A Rodriguez Journal of Neurosurgery 132 (3), 802-808, 2019 | 17 | 2019 |
Evaluating N-benzylgalactonoamidines as putative transition state analogs for β-galactoside hydrolysis QH Fan, S Striegler, RG Langston, JD Barnett Organic & biomolecular chemistry 12 (17), 2792-2800, 2014 | 14 | 2014 |
Differences in stability, activity and mutation effects between human and mouse leucine-rich repeat kinase 2 RG Langston, IN Rudenko, R Kumaran, DN Hauser, A Kaganovich, ... Neurochemical research 44, 1446-1459, 2019 | 10 | 2019 |
Generation of fourteen isogenic cell lines for Parkinson’s disease-associated leucine-rich repeat kinase (LRRK2) A Beylina, RG Langston, D Rosen, X Reed, MR Cookson Stem cell research 53, 102354, 2021 | 9 | 2021 |
Pathways of protein synthesis and degradation in PD pathogenesis RG Langston, MR Cookson Progress in Brain Research 252, 217-270, 2020 | 7 | 2020 |
Use of a modified STROOP test to assess color discrimination deficit in Parkinson's disease RG Langston, T Virmani Frontiers in Neurology 9, 407689, 2018 | 7 | 2018 |
Recent trends in NIH funding for top surgeon-scientists RG Langston, EH Zhao, KH Wong, A Rodriguez The American Journal of Surgery 222 (2), 281-285, 2021 | 6 | 2021 |
Divergent patterns of healthy aging across human brain regions at single-cell resolution reveal links to neurodegenerative disease MF Duffy, J Ding, RG Langston, SI Shah, MA Nalls, SW Scholz, ... bioRxiv, 2023 | 5 | 2023 |