| Ageing as a risk factor for neurodegenerative disease Y Hou, X Dan, M Babbar, Y Wei, SG Hasselbalch, DL Croteau, VA Bohr Nature Reviews Neurology 15 (10), 565-581, 2019 | 1991 | 2019 |
| Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer’s disease EF Fang, Y Hou, K Palikaras, BA Adriaanse, JS Kerr, B Yang, S Lautrup, ... Nature neuroscience 22 (3), 401-412, 2019 | 1135 | 2019 |
| NAD+ in aging: molecular mechanisms and translational implications EF Fang, S Lautrup, Y Hou, TG Demarest, DL Croteau, MP Mattson, ... Trends in molecular medicine 23 (10), 899-916, 2017 | 431 | 2017 |
| NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency Y Hou, S Lautrup, S Cordonnier, Y Wang, DL Croteau, E Zavala, Y Zhang, ... Proceedings of the National Academy of Sciences 115 (8), E1876-E1885, 2018 | 397 | 2018 |
| NAD+ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer’s disease via cGAS–STING Y Hou, Y Wei, S Lautrup, B Yang, Y Wang, S Cordonnier, MP Mattson, ... Proceedings of the National Academy of Sciences 118 (37), e2011226118, 2021 | 211 | 2021 |
| NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome EF Fang, Y Hou, S Lautrup, MB Jensen, B Yang, T SenGupta, D Caponio, ... Nature communications 10 (1), 5284, 2019 | 187 | 2019 |
| Genome instability in Alzheimer disease Y Hou, H Song, DL Croteau, M Akbari, VA Bohr Mechanisms of Ageing and Development 161, 83-94, 2017 | 112 | 2017 |
| Toward understanding genomic instability, mitochondrial dysfunction and aging NB Fakouri, Y Hou, TG Demarest, LS Christiansen, MN Okur, JG Mohanty, ... The FEBS Journal 286 (6), 1058-1073, 2019 | 66 | 2019 |
| NAD+ supplementation prevents STING‐induced senescence in ataxia telangiectasia by improving mitophagy B Yang, X Dan, Y Hou, JH Lee, N Wechter, S Krishnamurthy, R Kimura, ... Aging Cell 20 (4), e13329, 2021 | 59 | 2021 |
| Traditional Chinese Nootropic Medicine Radix Polygalae and Its Active Constituent Onjisaponin B Reduce β-Amyloid Production and Improve Cognitive Impairments X Li, J Cui, Y Yu, W Li, Y Hou, X Wang, D Qin, C Zhao, X Yao, J Zhao, ... PLoS One 11 (3), e0151147, 2016 | 47 | 2016 |
| Smart Soup, a traditional Chinese medicine formula, ameliorates amyloid pathology and related cognitive deficits Y Hou, Y Wang, J Zhao, X Li, J Cui, J Ding, Y Wang, X Zeng, Y Ling, ... PloS one 9 (11), e111215, 2014 | 39 | 2014 |
| In vitro and in vivo detection of mitophagy in human cells, C. elegans, and mice EF Fang, K Palikaras, N Sun, EM Fivenson, RD Spangler, JS Kerr, ... JoVE (Journal of Visualized Experiments), e56301, 2017 | 38 | 2017 |
| NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress B Yang, DM Figueroa, Y Hou, M Babbar, SL Baringer, DL Croteau, ... Free Radical Biology and Medicine 141, 47-58, 2019 | 20 | 2019 |
| Alzheimer’s amyloid-β accelerates human neuronal cell senescence which could be rescued by Sirtuin-1 and aspirin Y Li, J Lu, Y Hou, S Huang, G Pei Frontiers in Cellular Neuroscience 16, 906270, 2022 | 13 | 2022 |
| Alzheimer’s Amyloid-β Accelerates Cell Senescence and Suppresses the SIRT1/NRF2 Pathway in Human Microglial Cells Y An, Y Li, Y Hou, S Huang, G Pei Oxidative Medicine and Cellular Longevity 2022, 2022 | 12 | 2022 |
| Nicotinamide adenine dinucleotide supplementation drives gut microbiota variation in Alzheimer’s mouse model X Chu, Y Hou, Q Meng, DL Croteau, Y Wei, S De, KG Becker, VA Bohr Frontiers in Aging Neuroscience 14, 993615, 2022 | 8 | 2022 |
| Roles of NAD+ in Health and Aging S Lautrup, Y Hou, EF Fang, VA Bohr Cold Spring Harbor Perspectives in Medicine 14 (1), a041193, 2024 | 3 | 2024 |
| TGFβR-1/ALK5 inhibitor RepSox induces enteric glia-to-neuron transition and influences gastrointestinal mobility in adult mice C Shi, J Lian, B Zhang, J Cha, Q Hua, X Pi, Y Hou, X Xie, R Zhang Acta Pharmacologica Sinica 44 (1), 92-104, 2023 | 2 | 2023 |
| The cGAS-STING signaling pathway is modulated by urolithin A HB Madsen, JH Park, X Chu, Y Hou, Z Li, LJ Rasmussen, DL Croteau, ... Mechanisms of Ageing and Development 217, 111897, 2024 | 1 | 2024 |
| RecQ dysfunction contributes to social and depressive-like behavior and affects aldolase activity in mice Y Hou, JH Park, X Dan, X Chu, B Yang, M Hussain, DL Croteau, VA Bohr Neurobiology of Disease 180, 106092, 2023 | 1 | 2023 |
Deborah L CroteauNational Institute on Aging, NIHVerified email at nih.gov
