Alex O'Neill
Alex O'Neill
Professor of Antimicrobial Research, University of Leeds
Verified email at - Homepage
Cited by
Cited by
Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections
JG Hurdle, AJ O'Neill, I Chopra, RE Lee
Nature Reviews Microbiology 9 (1), 62-75, 2011
Mechanistic investigation into antibacterial behaviour of suspensions of ZnO nanoparticles against E. coli
L Zhang, Y Jiang, Y Ding, N Daskalakis, L Jeuken, M Povey, AJ O’neill, ...
Journal of Nanoparticle Research 12, 1625-1636, 2010
Staphylococcus aureus biofilms promote horizontal transfer of antibiotic resistance
VJ Savage, I Chopra, AJ O'Neill
Antimicrobial agents and chemotherapy 57 (4), 1968-1970, 2013
Treatment of health-care-associated infections caused by Gram-negative bacteria: a consensus statement
I Chopra, C Schofield, M Everett, A O'Neill, K Miller, M Wilcox, JM Frère, ...
The Lancet infectious diseases 8 (2), 133-139, 2008
Increased mutability of Pseudomonas aeruginosa in biofilms
K Driffield, K Miller, JM Bostock, AJ O'neill, I Chopra
Journal of antimicrobial chemotherapy 61 (5), 1053-1056, 2008
The role of mutators in the emergence of antibiotic-resistant bacteria
I Chopra, AJ O’Neill, K Miller
Drug Resistance Updates 6 (3), 137-145, 2003
Silver resistance in Gram-negative bacteria: a dissection of endogenous and exogenous mechanisms
CP Randall, A Gupta, N Jackson, D Busse, AJ O'neill
Journal of Antimicrobial Chemotherapy 70 (4), 1037-1046, 2015
Prospects for aminoacyl-tRNA synthetase inhibitors as new antimicrobial agents
JG Hurdle, AJ O'Neill, I Chopra
Antimicrobial agents and chemotherapy 49 (12), 4821-4833, 2005
ABC-F proteins mediate antibiotic resistance through ribosomal protection
LKR Sharkey, TA Edwards, AJ O’Neill
mBio 7 (2), e01975-15, 2016
Exploiting current understanding of antibiotic action for discovery of new drugs
I Chopra, L Hesse, AJ O'Neill
Journal of applied microbiology 92 (s1), 4S-15S, 2002
The target of daptomycin is absent from Escherichia coli and other gram-negative pathogens
CP Randall, KR Mariner, I Chopra, AJ O'Neill
Antimicrobial agents and chemotherapy 57 (1), 637-639, 2013
Analysis of mupirocin resistance and fitness in Staphylococcus aureus by molecular genetic and structural modeling techniques
JG Hurdle, AJ O'neill, E Ingham, C Fishwick, I Chopra
Antimicrobial agents and chemotherapy 48 (11), 4366-4376, 2004
Consequences of daptomycin-mediated membrane damage in Staphylococcus aureus
JK Hobbs, K Miller, AJ O’neill, I Chopra
Journal of antimicrobial chemotherapy 62 (5), 1003-1008, 2008
Mutation frequencies for resistance to fusidic acid and rifampicin in Staphylococcus aureus
AJ O'Neill, JH Cove, I Chopra
Journal of Antimicrobial Chemotherapy 47 (5), 647-650, 2001
Preclinical evaluation of novel antibacterial agents by microbiological and molecular techniques
AJ O’Neill, I Chopra
Expert opinion on investigational drugs 13 (8), 1045-1063, 2004
The silver cation (Ag+): antistaphylococcal activity, mode of action and resistance studies
CP Randall, LB Oyama, JM Bostock, I Chopra, AJ O'Neill
Journal of Antimicrobial Chemotherapy 68 (1), 131-138, 2013
Genetic basis of resistance to fusidic acid in staphylococci
AJ O'neill, F McLaws, G Kahlmeter, AS Henriksen, I Chopra
Antimicrobial agents and chemotherapy 51 (5), 1737-1740, 2007
Molecular genetic and structural modeling studies of Staphylococcus aureus RNA polymerase and the fitness of rifampin resistance genotypes in relation to clinical prevalence
AJ O'Neill, T Huovinen, CWG Fishwick, I Chopra
Antimicrobial agents and chemotherapy 50 (1), 298-309, 2006
Target protection as a key antibiotic resistance mechanism
DN Wilson, V Hauryliuk, GC Atkinson, AJ O’Neill
Nature Reviews Microbiology 18 (11), 637-648, 2020
In vivo transfer of high-level mupirocin resistance from Staphylococcus epidermidis to methicillin-resistant Staphylococcus aureus associated with failure of mupirocin prophylaxis
JG Hurdle, AJ O'Neill, L Mody, I Chopra, SF Bradley
Journal of Antimicrobial Chemotherapy 56 (6), 1166-1168, 2005
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