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Thomas Sheard
Thomas Sheard
Verified email at sheffield.ac.uk - Homepage
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Year
Three-dimensional and chemical mapping of intracellular signaling nanodomains in health and disease with enhanced expansion microscopy
TMD Sheard, ME Hurley, J Colyer, E White, R Norman, E Pervolaraki, ...
ACS nano 13 (2), 2143-2157, 2019
482019
A correlative super-resolution protocol to visualise structural underpinnings of fast second-messenger signalling in primary cell types
ME Hurley, TMD Sheard, R Norman, HM Kirton, SS Shah, E Pervolaraki, ...
Methods 193, 27-37, 2021
122021
3D ultrastructural organisation of calcium release units in the avian sarcoplasmic reticulum
TMD Sheard, SR Kharche, C Pinali, HA Shiels
Journal of Experimental Biology 222 (7), jeb197640, 2019
122019
Three-dimensional visualization of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads
TMD Sheard, ME Hurley, AJ Smith, J Colyer, E White, I Jayasinghe
Philosophical Transactions of the Royal Society B 377 (1864), 20210316, 2022
82022
Enhanced expansion microscopy to measure nanoscale structural and biochemical remodeling in single cells
TMD Sheard, I Jayasinghe
Methods in Cell Biology 161, 147-180, 2021
72021
Increased SERCA2a sub-cellular heterogeneity in right-ventricular heart failure inhibits excitation-contraction coupling and modulates arrhythmogenic dynamics
M Holmes, ME Hurley, TMD Sheard, AP Benson, I Jayasinghe, ...
Philosophical Transactions of the Royal Society B 377 (1864), 20210317, 2022
52022
Correlative super-resolution analysis of cardiac calcium sparks and their molecular origins in health and disease
ME Hurley, E White, TMD Sheard, D Steele, I Jayasinghe
Open Biology 13 (5), 230045, 2023
42023
Expansion microscopy reveals subdomains in C. elegans germ granules
KM Suen, TMD Sheard, CC Lin, D Milonaityte, I Jayasinghe, JE Ladbury
Life Science Alliance 6 (4), 2023
32023
Differential labelling of human sub-cellular compartments with fluorescent dye esters and expansion microscopy
TMD Sheard, TB Shakespeare, RS Seehra, ME Spencer, KM Suen, ...
Nanoscale 15 (45), 18489-18499, 2023
32023
Geometry-preserving expansion microscopy microplates enable high-fidelity nanoscale distortion mapping
RS Seehra, SJ Warrington, BHK Allouis, TMD Sheard, ME Spencer, ...
Cell Reports Physical Science 4 (12), 2023
22023
Molecular-scale 3D visualisation of the cardiac ryanodine receptor clusters and the molecular-scale fraying of dyads
TMD Sheard, ME Hurley, AJ Smith, J Colyer, E White, I Jayasinghe
BioRxiv, 2021.10. 21.462365, 2021
12021
Visualization of angiotensin II type 1 receptors in their native cellular organization by using expansion microscopy
YDLMZ Diaz, TMD Sheard, CB Andersen, I Jayasinghe, EA Christensen
Biophysical Journal 123 (3), 464a, 2024
2024
Super-Resolution Analysis of the Origins of the Elementary Events of ER Calcium Release in Dorsal Root Ganglion Neurons
ME Hurley, SS Shah, TMD Sheard, HM Kirton, DS Steele, N Gamper, ...
Cells 13 (1), 38, 2023
2023
Correction: Expansion microscopy reveals subdomains in C. elegans germ granules
KM Suen, TMD Sheard, CC Lin, D Milonaityte, I Jayasinghe, JE Ladbury
Life Science Alliance 7 (1), e202302405-e202302405, 2023
2023
Diverse labelling of cellular compartments with NHS esters in expansion microscopy
TMD Sheard, ME Spencer, T Shakespeare, RS Seehra, KM Suen, ...
Biophysical Journal 122 (3), 275a, 2023
2023
Angiotensin II Treatment Induces Reorganization and Changes in the Lateral Dynamics of Angiotensin II Type 1 Receptor in the Plasma Membrane Elucidated by Photoactivated …
C Andersen, YM Zulueta Díaz, JL Kure, M Hessellund Eriksen, AL Lovatt, ...
Analytical Chemistry 95 (2), 730-738, 2022
2022
Correlative super-resolution microscopy of intracellular calcium release channels and fast, cytoplasmic calcium signals
M Hurley, T Sheard, E White, D Steele, I Jayasinghe
ACTA PHYSIOLOGICA 236, 27-27, 2022
2022
Molecular-scale analysis of cardiac calcium nanodomains and remodelling using expansion microscopy
TMD Sheard
University of Leeds, 2021
2021
A super-resolution protocol to correlate structural underpinnings of fast second-messenger signalling in primary cell types
ME Hurley, TMD Sheard, R Norman, HM Kirton, SS Shah, E Pervolaraki, ...
bioRxiv, 2020.09. 29.319400, 2020
2020
Peptide ligands of the cardiac ryanodine receptor as super-resolution imaging probes
TMD Sheard, L Howlett, H Kirton, Z Yang, G Gurrola, D Steele, ...
bioRxiv, 2020.06. 26.131854, 2020
2020
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Articles 1–20