| Strategy and success for the directed evolution of enzymes PA Dalby Current opinion in structural biology 21 (4), 473-480, 2011 | 239 | 2011 |
| Optimising enzyme function by directed evolution PA Dalby Current opinion in structural biology 13 (4), 500-505, 2003 | 193 | 2003 |
| Accelerated design of bioconversion processes using automated microscale processing techniques GJ Lye, P Ayazi-Shamlou, F Baganz, PA Dalby, JM Woodley TRENDS in Biotechnology 21 (1), 29-37, 2003 | 182 | 2003 |
| One‐pot synthesis of amino‐alcohols using a de‐novo transketolase and β‐alanine: Pyruvate transaminase pathway in Escherichia coli CU Ingram, M Bommer, MEB Smith, PA Dalby, JM Ward, HC Hailes, ... Biotechnology and bioengineering 96 (3), 559-569, 2007 | 172 | 2007 |
| Two strategies to engineer flexible loops for improved enzyme thermostability H Yu, Y Yan, C Zhang, PA Dalby Scientific reports 7 (1), 41212, 2017 | 158 | 2017 |
| Directed evolution of biocatalytic processes EG Hibbert, F Baganz, HC Hailes, JM Ward, GJ Lye, JM Woodley, ... Biomolecular engineering 22 (1-3), 11-19, 2005 | 152 | 2005 |
| Directed evolution strategies for improved enzymatic performance EG Hibbert, PA Dalby Microbial Cell Factories 4, 1-6, 2005 | 121 | 2005 |
| Directed evolution of transketolase activity on non-phosphorylated substrates EG Hibbert, T Senussi, SJ Costelloe, W Lei, MEB Smith, JM Ward, ... Journal of biotechnology 131 (4), 425-432, 2007 | 104 | 2007 |
| A multidisciplinary approach toward the rapid and preparative-scale biocatalytic synthesis of chiral amino alcohols: a concise transketolase-/ω-transaminase-mediated synthesis … MEB Smith, BH Chen, EG Hibbert, U Kaulmann, K Smithies, JL Galman, ... Organic Process Research & Development 14 (1), 99-107, 2010 | 98 | 2010 |
| Directed evolution of transketolase substrate specificity towards an aliphatic aldehyde EG Hibbert, T Senussi, MEB Smith, SJ Costelloe, JM Ward, HC Hailes, ... Journal of biotechnology 134 (3-4), 240-245, 2008 | 91 | 2008 |
| Evolutionary analysis of the TPP-dependent enzyme family SJ Costelloe, JM Ward, PA Dalby Journal of molecular evolution 66, 36-49, 2008 | 89 | 2008 |
| Enhancing and Reversing the Stereoselectivity of Escherichia coli Transketolase via Single‐Point Mutations MEB Smith, EG Hibbert, AB Jones, PA Dalby, HC Hailes Advanced Synthesis & Catalysis 350 (16), 2631-2638, 2008 | 87 | 2008 |
| Non-α-hydroxylated aldehydes with evolved transketolase enzymes A Cázares, JL Galman, LG Crago, MEB Smith, J Strafford, L Ríos-Solís, ... Organic & biomolecular chemistry 8 (6), 1301-1309, 2010 | 86 | 2010 |
| High‐throughput measurement of protein stability in microtiter plates JP Aucamp, AM Cosme, GJ Lye, PA Dalby Biotechnology and Bioengineering 89 (5), 599-607, 2005 | 78 | 2005 |
| Engineering enzymes for biocatalysis PA Dalby Recent patents on biotechnology 1 (1), 1-9, 2007 | 76 | 2007 |
| Mapping the aggregation kinetics of a therapeutic antibody fragment N Chakroun, D Hilton, SS Ahmad, GW Platt, PA Dalby Molecular pharmaceutics 13 (2), 307-319, 2016 | 67 | 2016 |
| Folding intermediates of wild-type and mutants of barnase. I. Use of Φ-value analysis and m-values to probe the cooperative nature of the folding pre-equilibrium PA Dalby, M Oliveberg, AR Fersht Journal of molecular biology 276 (3), 625-646, 1998 | 67 | 1998 |
| Coupled molecular dynamics mediate long-and short-range epistasis between mutations that affect stability and aggregation kinetics H Yu, PA Dalby Proceedings of the National Academy of Sciences 115 (47), E11043-E11052, 2018 | 66 | 2018 |
| Identification and use of an alkane transporter plug-in for applications in biocatalysis and whole-cell biosensing of alkanes C Grant, D Deszcz, YC Wei, RJ MartInez-Torres, P Morris, T Folliard, ... Scientific reports 4 (1), 5844, 2014 | 66 | 2014 |
| Better biocatalytic processes faster: new tools for the implementation of biocatalysis in organic synthesis GJ Lye, PA Dalby, JM Woodley Organic process research & development 6 (4), 434-440, 2002 | 61 | 2002 |
