Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum MB Reed, KJ Saliba, SR Caruana, K Kirk, AF Cowman Nature 403 (6772), 906-909, 2000 | 1064 | 2000 |
Membrane transport in the malaria-infected erythrocyte K Kirk Physiological reviews 81 (2), 495-537, 2001 | 511 | 2001 |
Chloroquine transport via the malaria parasite’s chloroquine resistance transporter RE Martin, RV Marchetti, AI Cowan, SM Howitt, S Bröer, K Kirk science 325 (5948), 1680-1682, 2009 | 373 | 2009 |
Transport of diverse substrates into malaria-infected erythrocytes via a pathway showing functional characteristics of a chloride channel. K Kirk, HA Horner, BC Elford, JC Ellory, CI Newbold Journal of Biological Chemistry 269 (5), 3339-3347, 1994 | 284 | 1994 |
Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance PG Bray, RE Martin, L Tilley, SA Ward, K Kirk, DA Fidock Molecular microbiology 56 (2), 323-333, 2005 | 267 | 2005 |
Calothrixins A and B, novel pentacyclic metabolites from Calothrix cyanobacteria with potent activity against malaria parasites and human cancer cells RW Rickards, JM Rothschild, AC Willis, NM de Chazal, J Kirk, K Kirk, ... Tetrahedron 55 (47), 13513-13520, 1999 | 257 | 1999 |
The malaria parasite's chloroquine resistance transporter is a member of the drug/metabolite transporter superfamily RE Martin, K Kirk Molecular biology and evolution 21 (10), 1938-1949, 2004 | 255 | 2004 |
Transport and metabolism of the essential vitamin pantothenic acid in human erythrocytes infected with the malaria parasite Plasmodium falciparum KJ Saliba, HA Horner, K Kirk Journal of Biological Chemistry 273 (17), 10190-10195, 1998 | 255 | 1998 |
Coenzyme A biosynthesis: an antimicrobial drug target C Spry, K Kirk, KJ Saliba FEMS microbiology reviews 32 (1), 56-106, 2008 | 250 | 2008 |
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 230 | 2016 |
A surface transporter family conveys the trypanosome differentiation signal S Dean, R Marchetti, K Kirk, KR Matthews Nature 459 (7244), 213-217, 2009 | 230 | 2009 |
(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium MB Jiménez-Díaz, D Ebert, Y Salinas, A Pradhan, AM Lehane, ... Proceedings of the National Academy of Sciences 111 (50), E5455-E5462, 2014 | 214 | 2014 |
Na+ regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarials NJ Spillman, RJW Allen, CW McNamara, BKS Yeung, EA Winzeler, ... Cell host & microbe 13 (2), 227-237, 2013 | 200 | 2013 |
The'permeome'of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum RE Martin, RI Henry, JL Abbey, JD Clements, K Kirk Genome biology 6 (3), 1-22, 2005 | 200 | 2005 |
pH regulation in the intracellular malaria parasite, Plasmodium falciparum: H+ extrusion via a V-type H+-ATPase KJ Saliba, K Kirk Journal of Biological Chemistry 274 (47), 33213-33219, 1999 | 200 | 1999 |
Transport of organic substrates via a volume-activated channel. K Kirk, JC Ellory, JD Young Journal of Biological Chemistry 267 (33), 23475-23478, 1992 | 191 | 1992 |
The pH of the digestive vacuole of Plasmodium falciparum is not associated with chloroquine resistance R Hayward, KJ Saliba, K Kirk Journal of cell science 119 (6), 1016-1025, 2006 | 176 | 2006 |
Swelling-activated organic osmolyte channels K Kirk The Journal of membrane biology 158 (1), 1-16, 1997 | 170 | 1997 |
Swelling-activated and isoprenaline-activated chloride currents in guinea pig cardiac myocytes have distinct electrophysiology and pharmacology. JI Vandenberg, A Yoshida, K Kirk, T Powell The Journal of general physiology 104 (6), 997-1017, 1994 | 159 | 1994 |
The Plasmodium falciparum-infected red blood cell L Tilley, MWA Dixon, K Kirk The international journal of biochemistry & cell biology 43 (6), 839-842, 2011 | 156 | 2011 |