Kimberly Siegmund
Kimberly Siegmund
Professor of Biostatistics, University of Southern California
Verified email at
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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
DJ Weisenberger, KD Siegmund, M Campan, J Young, TI Long, ...
Nature genetics 38 (7), 787-793, 2006
A Big Bang model of human colorectal tumor growth
A Sottoriva, H Kang, Z Ma, TA Graham, MP Salomon, J Zhao, P Marjoram, ...
Nature genetics 47 (3), 209-216, 2015
Low-level processing of Illumina Infinium DNA methylation beadarrays
TJ Triche Jr, DJ Weisenberger, D Van Den Berg, PW Laird, KD Siegmund
Nucleic acids research 41 (7), e90-e90, 2013
DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons
KD Siegmund, CM Connor, M Campan, TI Long, DJ Weisenberger, ...
PloS one 2 (9), e895, 2007
Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression
SA Selamat, BS Chung, L Girard, W Zhang, Y Zhang, M Campan, ...
Genome research 22 (7), 1197-1211, 2012
Association of breast cancer DNA methylation profiles with hormone receptor status and response to tamoxifen
M Widschwendter, KD Siegmund, HM Müller, H Fiegl, C Marth, ...
Cancer research 64 (11), 3807-3813, 2004
Recommendations for the design and analysis of epigenome-wide association studies
KB Michels, AM Binder, S Dedeurwaerder, CB Epstein, JM Greally, I Gut, ...
Nature methods 10 (10), 949-955, 2013
Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human sperm
S Houshdaran, VK Cortessis, K Siegmund, A Yang, PW Laird, RZ Sokol
PloS one 2 (12), e1289, 2007
Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer
EM Wolff, HM Byun, HF Han, S Sharma, PW Nichols, KD Siegmund, ...
PLoS genetics 6 (4), e1000917, 2010
Environmental epigenetics: prospects for studying epigenetic mediation of exposure–response relationships
VK Cortessis, DC Thomas, AJ Levine, CV Breton, TM Mack, KD Siegmund, ...
Human genetics 131, 1565-1589, 2012
Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue-and individual-specific DNA methylation patterns
HM Byun, KD Siegmund, F Pan, DJ Weisenberger, G Kanel, PW Laird, ...
Human molecular genetics 18 (24), 4808-4817, 2009
Bis-SNP: combined DNA methylation and SNP calling for Bisulfite-seq data
Y Liu, KD Siegmund, PW Laird, BP Berman
Genome biology 13, 1-14, 2012
Molecular Characterization of MSI-H Colorectal Cancer by MLHI Promoter Methylation, Immunohistochemistry, and Mismatch Repair Germline Mutation Screening
JN Poynter, KD Siegmund, DJ Weisenberger, TI Long, SN Thibodeau, ...
Cancer Epidemiology Biomarkers & Prevention 17 (11), 3208-3215, 2008
Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients
MG Friedrich, DJ Weisenberger, JC Cheng, S Chandrasoma, ...
Clinical Cancer Research 10 (22), 7457-7465, 2004
Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue
EM Wolff, Y Chihara, F Pan, DJ Weisenberger, KD Siegmund, K Sugano, ...
Cancer research 70 (20), 8169-8178, 2010
The PREMM1, 2, 6 model predicts risk of MLH1, MSH2, and MSH6 germline mutations based on cancer history
F Kastrinos, EW Steyerberg, R Mercado, J Balmaña, S Holter, S Gallinger, ...
Gastroenterology 140 (1), 73-81. e5, 2011
Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers
KD Siegmund, P Marjoram, YJ Woo, S Tavaré, D Shibata
Proceedings of the National Academy of Sciences 106 (12), 4828-4833, 2009
The methylenetetrahydrofolate reductase 677C→ T polymorphism and distal colorectal adenoma risk
AJ Levine, KD Siegmund, CM Ervin, A Diep, ER Lee, HD Frankl, ...
Cancer Epidemiology Biomarkers & Prevention 9 (7), 657-663, 2000
Associations between smoking, alcohol consumption, and colorectal cancer, overall and by tumor microsatellite instability status
JN Poynter, RW Haile, KD Siegmund, PT Campbell, JC Figueiredo, ...
Cancer epidemiology, biomarkers & prevention 18 (10), 2745-2750, 2009
DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma
SA Selamat, JS Galler, AD Joshi, MN Fyfe, M Campan, KD Siegmund, ...
PloS one 6 (6), e21443, 2011
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