Stephen Thorpe
Cited by
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The response of bone marrow-derived mesenchymal stem cells to dynamic compression following TGF-β3 induced chondrogenic differentiation
SD Thorpe, CT Buckley, T Vinardell, FJ O’Brien, VA Campbell, DJ Kelly
Annals of biomedical engineering 38 (9), 2896-2909, 2010
Dynamic compression can inhibit chondrogenesis of mesenchymal stem cells
SD Thorpe, CT Buckley, T Vinardell, FJ O’Brien, VA Campbell, DJ Kelly
Biochemical and biophysical research communications 377 (2), 458-462, 2008
Functional properties of cartilaginous tissues engineered from infrapatellar fat pad-derived mesenchymal stem cells
CT Buckley, T Vinardell, SD Thorpe, MG Haugh, E Jones, D McGonagle, ...
Journal of biomechanics 43 (5), 920-926, 2010
The effect of concentration, thermal history and cell seeding density on the initial mechanical properties of agarose hydrogels
CT Buckley, SD Thorpe, FJ O’Brien, AJ Robinson, DJ Kelly
Journal of the mechanical behavior of biomedical materials 2 (5), 512-521, 2009
Biophysical regulation of chromatin architecture instills a mechanical memory in mesenchymal stem cells
SJ Heo, SD Thorpe, TP Driscoll, RL Duncan, DA Lee, RL Mauck
Scientific reports 5, 16895, 2015
Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression
EG Meyer, CT Buckley, SD Thorpe, DJ Kelly
Journal of biomechanics 43 (13), 2516-2523, 2010
Continuous and uninterrupted oxygen tension influences the colony formation and oxidative metabolism of human mesenchymal stem cells
G Pattappa, SD Thorpe, NC Jegard, HK Heywood, JD de Bruijn, DA Lee
Tissue Engineering Part C: Methods 19 (1), 68-79, 2013
Chondrogenesis and integration of mesenchymal stem cells within an in vitro cartilage defect repair model
T Vinardell, SD Thorpe, CT Buckley, DJ Kelly
Annals of biomedical engineering 37 (12), 2556, 2009
Differentiation alters stem cell nuclear architecture, mechanics, and mechano-sensitivity
SJ Heo, TP Driscoll, SD Thorpe, NL Nerurkar, BM Baker, MT Yang, ...
Elife 5, e18207, 2016
Cell–matrix interactions regulate mesenchymal stem cell response to hydrostatic pressure
AJ Steward, SD Thorpe, T Vinardell, CT Buckley, DR Wagner, DJ Kelly
Acta Biomaterialia 8 (6), 2153-2159, 2012
Modulating gradients in regulatory signals within mesenchymal stem cell seeded hydrogels: a novel strategy to engineer zonal articular cartilage
SD Thorpe, T Nagel, SF Carroll, DJ Kelly
PLoS One 8 (4), e60764, 2013
Temporal and spatial changes in cartilage-matrix-specific gene expression in mesenchymal stem cells in response to dynamic compression
MG Haugh, EG Meyer, SD Thorpe, T Vinardell, GP Duffy, DJ Kelly
Tissue Engineering Part A 17 (23-24), 3085-3093, 2011
Engineering of large cartilaginous tissues through the use of microchanneled hydrogels and rotational culture
CT Buckley, SD Thorpe, DJ Kelly
Tissue Engineering Part A 15 (11), 3213-3220, 2009
Composition–function relations of cartilaginous tissues engineered from chondrocytes and mesenchymal stem cells isolated from bone marrow and infrapatellar fat pad
T Vinardell, CT Buckley, SD Thorpe, DJ Kelly
Journal of tissue engineering and regenerative medicine 5 (9), 673-683, 2011
European Society of Biomechanics SM Perren Award 2012: The external mechanical environment can override the influence of local substrate in determining stem cell fate
SD Thorpe, CT Buckley, AJ Steward, DJ Kelly
Journal of Biomechanics 45 (15), 2483-2492, 2012
Stem cell differentiation increases membrane-actin adhesion regulating cell blebability, migration and mechanics
K Sliogeryte, SD Thorpe, DA Lee, L Botto, MM Knight
Scientific reports 4 (1), 1-9, 2014
Adipogenic differentiation of hMSCs is mediated by recruitment of IGF‐1r onto the primary cilium associated with cilia elongation
MT Dalbay, SD Thorpe, JT Connelly, JP Chapple, MM Knight
Stem Cells 33 (6), 1952-1961, 2015
Dynamic regulation of nuclear architecture and mechanics—a rheostatic role for the nucleus in tailoring cellular mechanosensitivity
SD Thorpe, DA Lee
Nucleus 8 (3), 287-300, 2017
GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment
E Cortes, M Sarper, B Robinson, D Lachowski, A Chronopoulos, ...
EMBO reports 20 (1), e46556, 2019
Differential effects of LifeAct-GFP and actin-GFP on cell mechanics assessed using micropipette aspiration
K Sliogeryte, SD Thorpe, Z Wang, CL Thompson, N Gavara, MM Knight
Journal of biomechanics 49 (2), 310-317, 2016
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