| Engineered CAR T cells targeting the cancer-associated Tn-glycoform of the membrane mucin MUC1 control adenocarcinoma AD Posey Jr, RD Schwab, AC Boesteanu, C Steentoft, U Mandel, ... Immunity 44 (6), 1444-1454, 2016 | 583 | 2016 |
| Engineered CAR T cells targeting the cancer-associated Tn-glycoform of the membrane mucin MUC1 control adenocarcinoma AD Posey Jr, RD Schwab, AC Boesteanu, C Steentoft, U Mandel, ... Immunity 44 (6), 1444-1454, 2016 | 583 | 2016 |
| T‐cell receptor binding affinities and kinetics: impact on T‐cell activity and specificity JD Stone, AS Chervin, DM Kranz Immunology 126 (2), 165-176, 2009 | 475 | 2009 |
| Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains DT Harris, MV Hager, SN Smith, Q Cai, JD Stone, P Kruger, M Lever, ... The Journal of Immunology 200 (3), 1088-1100, 2018 | 154 | 2018 |
| A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs) JD Stone, DH Aggen, A Schietinger, H Schreiber, DM Kranz Oncoimmunology 1 (6), 863-873, 2012 | 125 | 2012 |
| Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies JD Stone, DM Kranz Investigating and harnessing T-cell functions with engineered immune …, 2015 | 124 | 2015 |
| TCR affinity for p/MHC formed by tumor antigens that are self-proteins: impact on efficacy and toxicity JD Stone, DT Harris, DM Kranz Current Opinion in Immunology 33, 16-22, 2015 | 117 | 2015 |
| HLA-restricted epitope identification and detection of functional T cell responses by using MHC–peptide and costimulatory microarrays JD Stone, WE Demkowicz, LJ Stern Proceedings of the National Academy of Sciences of the United States of …, 2005 | 109 | 2005 |
| The impact of TCR-binding properties and antigen presentation format on T cell responsiveness AS Chervin, JD Stone, PD Holler, A Bai, J Chen, HN Eisen, DM Kranz The Journal of Immunology 183 (2), 1166-1178, 2009 | 107 | 2009 |
| Soluble peptide–MHC monomers cause activation of CD8+ T cells through transfer of the peptide to T cell MHC molecules Q Ge, JD Stone, MT Thompson, JR Cochran, M Rushe, HN Eisen, J Chen, ... Proceedings of the National Academy of Sciences 99 (21), 13729-13734, 2002 | 92 | 2002 |
| Receptor proximity, not intermolecular orientation, is critical for triggering T-cell activation JR Cochran, TO Cameron, JD Stone, JB Lubetsky, LJ Stern Journal of Biological Chemistry 276 (30), 28068-28074, 2001 | 88 | 2001 |
| Noble metals strip peptides from class II MHC proteins SL De Wall, C Painter, JD Stone, R Bandaranayake, DC Wiley, ... Nature chemical biology 2 (4), 197, 2006 | 85 | 2006 |
| Single-chain VαVβ T-cell receptors function without mispairing with endogenous TCR chains DH Aggen, AS Chervin, TM Schmitt, B Engels, JD Stone, SA Richman, ... Gene therapy 19 (4), 365, 2012 | 77 | 2012 |
| Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation LL Jones, LA Colf, JD Stone, KC Garcia, DM Kranz The Journal of Immunology 181 (9), 6255-6264, 2008 | 74 | 2008 |
| T-cell activation by soluble MHC oligomers can be described by a two-parameter binding model JD Stone, JR Cochran, LJ Stern Biophysical journal 81 (5), 2547-2557, 2001 | 56 | 2001 |
| CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement JD Stone, LJ Stern The Journal of Immunology 176 (3), 1498-1505, 2006 | 54 | 2006 |
| T cell receptor engineering JD Stone, AS Chervin, DH Aggen, DM Kranz Methods in enzymology 503, 189-222, 2012 | 52 | 2012 |
| A novel T cell receptor single-chain signaling complex mediates antigen-specific T cell activity and tumor control JD Stone, DT Harris, CM Soto, AS Chervin, DH Aggen, EJ Roy, DM Kranz Cancer Immunology, Immunotherapy, 1-14, 2014 | 46 | 2014 |
| Interaction of streptavidin-based peptide–MHC oligomers (tetramers) with cell-surface TCRs JD Stone, MN Artyomov, AS Chervin, AK Chakraborty, HN Eisen, ... The Journal of Immunology 187 (12), 6281-6290, 2011 | 40 | 2011 |
| Exploration of the P6/P7 region of the peptide-binding site of the human class II major histocompatability complex protein HLA-DR1 Z Zavala-Ruiz, EJ Sundberg, JD Stone, DB DeOliveira, IC Chan, ... Journal of Biological Chemistry 278 (45), 44904-44912, 2003 | 40 | 2003 |
Adam ChervinUniversity of IllinoisVerified email at life.illinois.edu
