Sheikh Naeem Shafqat
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Short-chain dehydrogenases/reductases (SDR): the 2002 update
U Oppermann, C Filling, M Hult, N Shafqat, X Wu, M Lindh, J Shafqat, ...
Chemico-biological interactions 143, 247-253, 2003
Expanded substrate screenings of human and Drosophila type 10 17β-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism …
N Shafqat, HU Marschall, C Filling, E Nordling, XQ Wu, L Björk, J Thyberg, ...
Biochemical Journal 376 (1), 49-60, 2003
Human and rodent type 1 11β-hydroxysteroid dehydrogenases are 7β-hydroxycholesterol dehydrogenases involved in oxysterol metabolism
M Hult, B Elleby, N Shafqat, S Svensson, A Rane, H Jörnvall, ...
Cellular and Molecular Life Sciences CMLS 61 (7), 992-999, 2004
A non‐enzymatic function of 17β‐hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival
K Rauschenberger, K Schöler, JO Sass, S Sauer, Z Djuric, C Rumig, ...
EMBO molecular medicine 2 (2), 51-62, 2010
Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits.
N Shafqat, JR Muniz, ES Pilka, E Papagrigoriou, F von Delft, ...
Biochem. J 452, 27-36, 2013
Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3
S Porté, E Valencia, EA Yakovtseva, E Borràs, N Shafqat, JÉ Debreczeny, ...
Journal of Biological Chemistry 284 (25), 17194-17205, 2009
Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design
N Shafqat, A Turnbull, J Zschocke, U Oppermann, WW Yue
Journal of molecular biology 398 (4), 497-506, 2010
Active site variability of type 1 11β-hydroxysteroid dehydrogenase revealed by selective inhibitors and cross-species comparisons
M Hult, N Shafqat, B Elleby, D Mitschke, S Svensson, M Forsgren, T Barf, ...
Molecular and cellular endocrinology 248 (1-2), 26-33, 2006
Comparative enzymology of 11β-hydroxysteroid dehydrogenase type 1 from glucocorticoid resistant (guinea pig) versus sensitive (human) species
N Shafqat, B Elleby, S Svensson, J Shafqat, H Jörnvall, L Abrahmsen, ...
Journal of Biological Chemistry 278 (3), 2030-2035, 2003
Hep27, a member of the short-chain dehydrogenase/reductase family, is an NADPH-dependent dicarbonyl reductase expressed in vascular endothelial tissue
N Shafqat, J Shafqat, G Eissner, HU Marschall, K Tryggvason, U Eriksson, ...
Cellular and Molecular Life Sciences CMLS 63 (10), 1205-1213, 2006
Adenosine‐5′‐phosphosulfate–a multifaceted modulator of bifunctional 3′‐phospho‐adenosine‐5′‐phosphosulfate synthases and related enzymes
JW Mueller, N Shafqat
The FEBS journal 280 (13), 3050-3057, 2013
Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure–activity relationships
C Bhatia, S Oerum, J Bray, KL Kavanagh, N Shafqat, W Yue, ...
Chemico-biological interactions 234, 114-125, 2015
Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS
A Chaikuad, N Shafqat, R Al-Mokhtar, G Cameron, AR Clarke, RL Brady, ...
Biochemical Journal 435 (2), 401-409, 2011
A structural mapping of mutations causing succinyl-CoA: 3-ketoacid CoA transferase (SCOT) deficiency
N Shafqat, KL Kavanagh, JO Sass, E Christensen, T Fukao, WH Lee, ...
Journal of inherited metabolic disease 36 (6), 983-987, 2013
Subcellular targeting analysis of SDR-type hydroxysteroid dehydrogenases
C Filling, X Wu, N Shafqat, M Hult, E Mårtensson, J Shafqat, ...
Molecular and cellular endocrinology 171 (1-2), 99-101, 2001
Evaluation of micro-parallel liquid chromatography as a method for HTS-coupled actives verification
A Simeonov, A Yasgar, C Klumpp, W Zheng, N Shafqat, U Oppermann, ...
Assay and drug development technologies 5 (6), 815-824, 2007
U Oppermann, C Filling, M Hult, N Shafqat, X Wu, M Lindh, J Shafqat, ...
Chem. Biol. Interact 143, 247-253, 2003
Crystal Structure Of Human 17-Beta-Hydroxysteroid Dehydrogenase Type 4 In Complex With NAD
Lukacik, P., Shafqat, N., Kavanagh, K., Bray, J., Von Delft, F., Edwards, A ...
Protein Data Bank, 2005
SDR goes SGC: a structural genomics initiative
U Oppermann, K Kavanagh, KD Guo, S Ng, P Lukacik, XQ Wu, ...
Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment
A Azizi, NH Mumin, N Shafqat
F1000Research 10 (221), 221, 2021
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