| Short-chain dehydrogenases/reductases (SDR): the 2002 update U Oppermann, C Filling, M Hult, N Shafqat, X Wu, M Lindh, J Shafqat, ... Chemico-biological interactions 143, 247-253, 2003 | 761 | 2003 |
| Expanded substrate screenings of human and Drosophila type 10 17β-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism … N Shafqat, HU Marschall, C Filling, E Nordling, XQ Wu, L Björk, J Thyberg, ... Biochemical Journal 376 (1), 49-60, 2003 | 116 | 2003 |
| A non‐enzymatic function of 17β‐hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival K Rauschenberger, K Schöler, JO Sass, S Sauer, Z Djuric, C Rumig, ... EMBO molecular medicine 2 (2), 51-62, 2010 | 102 | 2010 |
| Human and rodent type 1 11β-hydroxysteroid dehydrogenases are 7β-hydroxycholesterol dehydrogenases involved in oxysterol metabolism M Hult, B Elleby, N Shafqat, S Svensson, A Rane, H Jörnvall, ... Cellular and Molecular Life Sciences CMLS 61, 992-999, 2004 | 97 | 2004 |
| Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits. N Shafqat, JR Muniz, ES Pilka, E Papagrigoriou, F von Delft, ... Biochem. J 452, 27-36, 2013 | 80 | 2013 |
| Three-dimensional structure and enzymatic function of proapoptotic human p53-inducible quinone oxidoreductase PIG3 S Porté, E Valencia, EA Yakovtseva, E Borras, N Shafqat, JÉ Debreczeny, ... Journal of biological chemistry 284 (25), 17194-17205, 2009 | 70 | 2009 |
| Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design N Shafqat, A Turnbull, J Zschocke, U Oppermann, WW Yue Journal of molecular biology 398 (4), 497-506, 2010 | 65 | 2010 |
| Hep27, a member of the short-chain dehydrogenase/reductase family, is an NADPH-dependent dicarbonyl reductase expressed in vascular endothelial tissue N Shafqat, J Shafqat, G Eissner, HU Marschall, K Tryggvason, U Eriksson, ... Cellular and Molecular Life Sciences CMLS 63 (10), 1205-1213, 2006 | 52 | 2006 |
| Adenosine‐5′‐phosphosulfate–a multifaceted modulator of bifunctional 3′‐phospho‐adenosine‐5′‐phosphosulfate synthases and related enzymes JW Mueller, N Shafqat The FEBS journal 280 (13), 3050-3057, 2013 | 50 | 2013 |
| Active site variability of type 1 11β-hydroxysteroid dehydrogenase revealed by selective inhibitors and cross-species comparisons M Hult, N Shafqat, B Elleby, D Mitschke, S Svensson, M Forsgren, T Barf, ... Molecular and Cellular Endocrinology 248 (1-2), 26-33, 2006 | 50 | 2006 |
| Comparative enzymology of 11β-hydroxysteroid dehydrogenase type 1 from glucocorticoid resistant (guinea pig) versus sensitive (human) species N Shafqat, B Elleby, S Svensson, J Shafqat, H Jörnvall, L Abrahmsen, ... Journal of Biological Chemistry 278 (3), 2030-2035, 2003 | 41 | 2003 |
| Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure–activity relationships C Bhatia, S Oerum, J Bray, KL Kavanagh, N Shafqat, W Yue, ... Chemico-biological interactions 234, 114-125, 2015 | 38 | 2015 |
| Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS A Chaikuad, N Shafqat, R Al-Mokhtar, G Cameron, AR Clarke, RL Brady, ... Biochemical journal 435 (2), 401-409, 2011 | 36 | 2011 |
| A structural mapping of mutations causing succinyl-CoA: 3-ketoacid CoA transferase (SCOT) deficiency N Shafqat, KL Kavanagh, JO Sass, E Christensen, T Fukao, WH Lee, ... Journal of inherited metabolic disease 36, 983-987, 2013 | 34 | 2013 |
| Kinetic and structural evidence of the alkenal/one reductase specificity of human ζ-crystallin S Porté, A Moeini, I Reche, N Shafqat, U Oppermann, J Farrés, X Parés Cellular and Molecular Life Sciences 68 (6), 1065 - 1077, 2011 | 20 | 2011 |
| Subcellular targeting analysis of SDR-type hydroxysteroid dehydrogenases C Filling, X Wu, N Shafqat, M Hult, E Mårtensson, J Shafqat, ... Molecular and cellular endocrinology 171 (1-2), 99-101, 2001 | 14 | 2001 |
| Phytochemicals with anti 5-alpha-reductase activity: a prospective for prostate cancer treatment A Azizi, NH Mumin, N Shafqat F1000Research 10, 2021 | 12 | 2021 |
| Role of Immunotherapy in the treatment of cancer: A systematic review SP Ling, LC Ming, JS Dhaliwal, M Gupta, C Ardianto, KW Goh, Z Hussain, ... Cancers 14 (21), 5205, 2022 | 8 | 2022 |
| Knowledge, attitude and practice towards the use of over-the-counter medicines: An online survey among Bruneian adults amid the COVID-19 pandemic FBS Bahrin Dzulkharnain, N Shafqat, A Hermansyah, CS Tan, D Koh, ... Sustainability 14 (15), 9033, 2022 | 5 | 2022 |
| Evaluation of micro-parallel liquid chromatography as a method for HTS-coupled actives verification A Simeonov, A Yasgar, C Klumpp, W Zheng, N Shafqat, U Oppermann, ... Assay and drug development technologies 5 (6), 815-824, 2007 | 5 | 2007 |
Frank von DelftPrincipal Investigator: Protein Crystallography, SGC, Oxford UniversityVerified email at sgc.ox.ac.uk
