Leonardo Bottolo
Leonardo Bottolo
Reader in Statistics for Biomedicine, Dept of Medical Genetics, University of Cambridge
Verified email at cam.ac.uk
Title
Cited by
Cited by
Year
A second generation human haplotype map of over 3.1 million SNPs
International HapMap Consortium
Nature 449 (7164), 851, 2007
8077*2007
Sure independence screening for ultrahigh dimensional feature space
J Fan, J Lv
Journal of the Royal Statistical Society: Series B (Statistical Methodology …, 2008
19312008
Genome-wide detection and characterization of positive selection in human populations
PC Sabeti, P Varilly, B Fry, J Lohmueller, E Hostetter, C Cotsapas, X Xie, ...
Nature 449 (7164), 913-918, 2007
15602007
A fine-scale map of recombination rates and hotspots across the human genome
S Myers, L Bottolo, C Freeman, G McVean, P Donnelly
Science 310 (5746), 321-324, 2005
11042005
A haplotype map of the human genome
D Altshuler, P Donnelly, International HapMap Consortium
Nature 437 (7063), nature04226, 2005
10672005
A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk
M Heinig, E Petretto, C Wallace, L Bottolo, M Rotival, H Lu, Y Li, R Sarwar, ...
Nature 467 (7314), 460-464, 2010
2672010
Low copy number of the salivary amylase gene predisposes to obesity
M Falchi, JSES Moustafa, P Takousis, F Pesce, A Bonnefond, ...
Nature genetics 46 (5), 492-497, 2014
1952014
Evolutionary stochastic search for Bayesian model exploration
L Bottolo, S Richardson
Bayesian Analysis 5 (3), 583-618, 2010
1882010
Endonuclease G is a novel determinant of cardiac hypertrophy and mitochondrial function
C McDermott-Roe, J Ye, R Ahmed, XM Sun, A Serafín, J Ware, L Bottolo, ...
Nature 478 (7367), 114-118, 2011
1272011
Deciphering the complex: Methodological overview of statistical models to derive OMICS‐based biomarkers
M Chadeau‐Hyam, G Campanella, T Jombart, L Bottolo, L Portengen, ...
Environmental and molecular mutagenesis 54 (7), 542-557, 2013
1032013
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus
MR Johnson, J Behmoaras, L Bottolo, ML Krishnan, K Pernhorst, ...
Nature communications 6 (1), 1-11, 2015
982015
The distribution and causes of meiotic recombination in the human genome
S Myers, CCA Spencer, A Auton, L Bottolo, C Freeman, P Donnelly, ...
Biochemical Society Transactions 34 (4), 526-530, 2006
952006
Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease
MR Johnson, K Shkura, SR Langley, A Delahaye-Duriez, P Srivastava, ...
Nature neuroscience 19 (2), 223-232, 2016
872016
Bayesian detection of expression quantitative trait loci hot spots
L Bottolo, E Petretto, S Blankenberg, F Cambien, SA Cook, L Tiret, ...
Genetics 189 (4), 1449-1459, 2011
752011
New insights into the genetic control of gene expression using a Bayesian multi-tissue approach
E Petretto, L Bottolo, SR Langley, M Heinig, C McDermott-Roe, R Sarwar, ...
PLoS Comput Biol 6 (4), e1000737, 2010
682010
GUESS-ing polygenic associations with multiple phenotypes using a GPU-based evolutionary stochastic search algorithm
L Bottolo, M Chadeau-Hyam, DI Hastie, T Zeller, B Liquet, P Newcombe, ...
PLoS Genet 9 (8), e1003657, 2013
542013
Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue
AJ Walley, P Jacobson, M Falchi, L Bottolo, JC Andersson, E Petretto, ...
International journal of obesity 36 (1), 137-147, 2012
512012
Bayesian models for sparse regression analysis of high dimensional data
S Richardson, L Bottolo, JS Rosenthal
Bayesian Statistics 9, 539-569, 2010
502010
Multi-tissue analysis of co-expression networks by higher-order generalized singular value decomposition identifies functionally coherent transcriptional modules
X Xiao, A Moreno-Moral, M Rotival, L Bottolo, E Petretto
PLoS genet 10 (1), e1004006, 2014
452014
Bayesian analysis of extreme values by mixture modeling
L Bottolo, G Consonni, P Dellaportas, A Lijoi
Extremes 6 (1), 25-47, 2003
452003
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Articles 1–20