Identification of an Atg8-Atg3 Protein–Protein Interaction Inhibitor from the Medicines for Malaria Venture Malaria Box Active in Blood and Liver Stage Plasmodium falciparum … AUP Hain, D Bartee, NG Sanders, AS Miller, DJ Sullivan, J Levitskaya, ... Journal of medicinal chemistry 57 (11), 4521-4531, 2014 | 54 | 2014 |
Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues EL Varner, S Trefely, D Bartee, E von Krusenstiern, L Izzo, C Bekeova, ... Open Biology 10 (9), 200187, 2020 | 42 | 2020 |
PI3K drives the de novo synthesis of coenzyme A from vitamin B5 CC Dibble, SA Barritt, GE Perry, EC Lien, RC Geck, SE DuBois-Coyne, ... Nature 608 (7921), 192-198, 2022 | 36 | 2022 |
Targeting the Unique Mechanism of Bacterial 1-Deoxy-d-xylulose-5-phosphate Synthase D Bartee, CL Freel Meyers Biochemistry 57 (29), 4349-4356, 2018 | 34 | 2018 |
Toward Understanding the Chemistry and Biology of 1-Deoxy-d-xylulose 5-Phosphate (DXP) Synthase: A Unique Antimicrobial Target at the Heart of Bacterial Metabolism D Bartee, CL Freel Meyers Accounts of Chemical Research 51 (10), 2546-2555, 2018 | 31 | 2018 |
Site-Specific Synthesis of N4-Acetylcytidine in RNA Reveals Physiological Duplex Stabilization D Bartee, KD Nance, JL Meier Journal of the American Chemical Society 144 (8), 3487-3496, 2022 | 24 | 2022 |
Enamide Prodrugs of Acetyl Phosphonate Deoxy-d-xylulose-5-phosphate Synthase Inhibitors as Potent Antibacterial Agents D Bartee, S Sanders, PD Phillips, MJ Harrison, AT Koppisch, ... ACS infectious diseases 5 (3), 406-417, 2019 | 24 | 2019 |
Challenges and Hallmarks of Establishing Alkylacetylphosphonates as Probes of Bacterial 1-Deoxy-d-xylulose 5-Phosphate Synthase S Sanders, RJ Vierling, D Bartee, AA DeColli, MJ Harrison, JL Aklinski, ... ACS Infectious Diseases 3 (7), 467-478, 2017 | 24 | 2017 |
Hydroxybenzaldoximes Are D‐GAP‐Competitive Inhibitors of E. coli 1‐Deoxy‐D‐Xylulose‐5‐Phosphate Synthase D Bartee, F Morris, A Al‐khouja, CL Freel Meyers ChemBioChem 16 (12), 1771-1781, 2015 | 21 | 2015 |
Redox‐dependent lipoylation of mitochondrial proteins in Plasmodium falciparum GA Afanador, KA Matthews, D Bartee, JE Gisselberg, MS Walters, ... Molecular microbiology 94 (1), 156-171, 2014 | 20 | 2014 |
Growth medium-dependent antimicrobial activity of early stage MEP pathway inhibitors S Sanders, D Bartee, MJ Harrison, PD Phillips, AT Koppisch, ... PloS one 13 (5), e0197638, 2018 | 18 | 2018 |
Synthesis and Evaluation of Fluoroalkyl Phosphonyl Analogues of 2-C-Methylerythritol Phosphate as Substrates and Inhibitors of IspD from Human Pathogens D Bartee, MJ Wheadon, CL Freel Meyers The Journal of Organic Chemistry, 2018 | 16 | 2018 |
A novel lipoate attachment enzyme is shared by Plasmodium and Chlamydia species GA Afanador, AJ Guerra, RP Swift, RE Rodriguez, D Bartee, KA Matthews, ... Molecular Microbiology 106 (3), 439-451, 2017 | 14 | 2017 |
Arrow pushing in RNA modification sequencing D Bartee, ST Gamage, CN Link, JL Meier Chemical Society Reviews 50 (17), 9482-9502, 2021 | 9 | 2021 |
Direct anabolic metabolism of three-carbon propionate to a six-carbon metabolite occurs in vivo across tissues and species MT Doan, MD Neinast, EL Varner, KC Bedi, D Bartee, H Jiang, S Trefely, ... Journal of lipid research 63 (6), 2022 | 1 | 2022 |
Quantitative prospective and retrospective mass spectrometry of lactoyl-CoA in mammalian cells and tissues EL Varner, S Trefely, D Bartee, E von Krusenstiern, L Izzo, C Bekeova, ... BioRxiv, 2020.03. 15.992859, 2020 | 1 | 2020 |
Direct anabolic three carbon metabolism via propionate to a six carbon metabolite occurs in human heart and in vivo across mouse tissues MT Doan, MD Neinast, EL Varner, K Bedi, D Bartee, H Jiang, S Trefely, ... bioRxiv, 758706, 2019 | 1 | 2019 |
Investigating inhibitors of 1-deoxy-d-xylulose 5-phosphate synthase in a mouse model of UTI EC Chen, RL Shapiro, A Pal, D Bartee, K DeLong, DM Carter, ... Microbiology Spectrum, e03896-23, 2024 | | 2024 |
Towards new antimicrobials: Targeting bacterial central metabolism through inhibition of methylerythritol phosphate pathway enzymes DL Bartee Johns Hopkins University, 2018 | | 2018 |
IDENTIFICATION OF COMPOUNDS WHICH INHIBIT ATG8-ATG3 PROTEIN-PROTEIN INTERACTION AND THEIR USE AS ANTIPARASITICAL AGENTS J Bosch, AUP Hain, C Freel Meyers, D Bartee US Patent 20,170,044,150, 2017 | | 2017 |