T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility OY Borbulevych, KH Piepenbrink, BE Gloor, DR Scott, RF Sommese, ... Immunity 31 (6), 885-896, 2009 | 230 | 2009 |
TCRs used in cancer gene therapy cross-react with MART-1/Melan-A tumor antigens via distinct mechanisms OY Borbulevych, SM Santhanagopolan, M Hossain, BM Baker The Journal of Immunology 187 (5), 2453-2463, 2011 | 175 | 2011 |
Increased immunogenicity of an anchor-modified tumor-associated antigen is due to the enhanced stability of the peptide/MHC complex: implications for vaccine design OY Borbulevych, TK Baxter, Z Yu, NP Restifo, BM Baker The Journal of Immunology 174 (8), 4812-4820, 2005 | 143 | 2005 |
The trans influence of F, Cl, Br and I ligands in a series of square-planar Pd(II) complexes. Relative affinities of halide anions for the metal centre in trans-[(Ph3P)2Pd(Ph)X] JP Flemming, MC Pilon, OY Borbulevitch, MY Antipin, VV Grushin Inorganica Chimica Acta 280 (12), 87-98, 1998 | 122 | 1998 |
Structures of MART-126/27–35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition OY Borbulevych, FK Insaidoo, TK Baxter, DJ Powell Jr, LA Johnson, ... Journal of molecular biology 372 (5), 1123-1136, 2007 | 112 | 2007 |
Lipoxygenase interactions with natural flavonoid, quercetin, reveal a complex with protocatechuic acid in its X‐ray structure at 2.1 Å resolution OY Borbulevych, J Jankun, SH Selman, E Skrzypczak‐Jankun Proteins: structure, function, and bioinformatics 54 (1), 13-19, 2004 | 107 | 2004 |
Conformational melding permits a conserved binding geometry in TCR recognition of foreign and self molecular mimics OY Borbulevych, KH Piepenbrink, BM Baker The Journal of Immunology 186 (5), 2950-2958, 2011 | 97 | 2011 |
T cell receptor recognition via cooperative conformational plasticity SJ Gagnon, OY Borbulevych, RL Davis-Harrison, RV Turner, M Damirjian, ... Journal of molecular biology 363 (1), 228-243, 2006 | 90 | 2006 |
Disparate degrees of hypervariable loop flexibility control T-cell receptor cross-reactivity, specificity, and binding mechanism DR Scott, OY Borbulevych, KH Piepenbrink, SA Corcelli, BM Baker Journal of molecular biology 414 (3), 385-400, 2011 | 89 | 2011 |
Loss of T cell antigen recognition arising from changes in peptide and major histocompatibility complex protein flexibility: implications for vaccine design FK Insaidoo, OY Borbulevych, M Hossain, SM Santhanagopolan, ... Journal of Biological Chemistry 286 (46), 40163-40173, 2011 | 71 | 2011 |
Accurate macromolecular crystallographic refinement: incorporation of the linear scaling, semiempirical quantum-mechanics program DivCon into the PHENIX refinement package OY Borbulevych, JA Plumley, RI Martin, KM Merz, LM Westerhoff Acta Crystallographica Section D: Biological Crystallography 70 (5), 1233-1247, 2014 | 58 | 2014 |
Unraveling a hotspot for TCR recognition on HLA-A2: evidence against the existence of peptide-independent TCR binding determinants SJ Gagnon, OY Borbulevych, RL Davis-Harrison, TK Baxter, JR Clemens, ... Journal of molecular biology 353 (3), 556-573, 2005 | 50 | 2005 |
Experimental and theoretical study of the structure of N, N-dimethyl-4-nitroaniline derivatives as model compounds for non-linear optical organic materials OY Borbulevych, RD Clark, A Romero, L Tan, MY Antipin, VN Nesterov, ... Journal of Molecular Structure 604 (1), 73-86, 2002 | 50 | 2002 |
Probing dimerization and structural flexibility of mammalian lipoxygenases by small-angle X-ray scattering W Shang, I Ivanov, DI Svergun, OY Borbulevych, AM Aleem, S Stehling, ... Journal of molecular biology 409 (4), 654-668, 2011 | 47 | 2011 |
Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner KH Piepenbrink, OY Borbulevych, RF Sommese, J Clemens, ... Biochemical Journal 423 (3), 353-361, 2009 | 42 | 2009 |
Effect of crystal freezing and small-molecule binding on internal cavity size in a large protein: X-ray and docking studies of lipoxygenase at ambient and low temperature at 2 … E Skrzypczak-Jankun, OY Borbulevych, MI Zavodszky, MR Baranski, ... Acta Crystallographica Section D: Biological Crystallography 62 (7), 766-775, 2006 | 42 | 2006 |
Soybean lipoxygenase-3 in complex with 4-nitrocatechol E Skrzypczak-Jankun, OY Borbulevych, J Jankun Acta Crystallographica Section D: Biological Crystallography 60 (3), 613-615, 2004 | 41 | 2004 |
Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A* 0201: implications for WT1-based cancer therapeutics OY Borbulevych, P Do, BM Baker Molecular immunology 47 (15), 2519-2524, 2010 | 37 | 2010 |
Increased peptide contacts govern high affinity binding of a modified TCR whilst maintaining a native pMHC docking mode DK Cole, M Sami, DR Scott, PJ Rizkallah, OY Borbulevych, PT Todorov, ... Frontiers in immunology 4, 168, 2013 | 36 | 2013 |
Lysine Nζ-decarboxylation switch and activation of the β-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus O Borbulevych, M Kumarasiri, B Wilson, LI Llarrull, M Lee, D Hesek, Q Shi, ... Journal of Biological Chemistry 286 (36), 31466-31472, 2011 | 31 | 2011 |