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Oleg Borbulevych
Oleg Borbulevych
QuantumBio Inc.
Verified email at quantumbioinc.com - Homepage
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Cited by
Year
T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility
OY Borbulevych, KH Piepenbrink, BE Gloor, DR Scott, RF Sommese, ...
Immunity 31 (6), 885-896, 2009
2302009
TCRs used in cancer gene therapy cross-react with MART-1/Melan-A tumor antigens via distinct mechanisms
OY Borbulevych, SM Santhanagopolan, M Hossain, BM Baker
The Journal of Immunology 187 (5), 2453-2463, 2011
1752011
Increased immunogenicity of an anchor-modified tumor-associated antigen is due to the enhanced stability of the peptide/MHC complex: implications for vaccine design
OY Borbulevych, TK Baxter, Z Yu, NP Restifo, BM Baker
The Journal of Immunology 174 (8), 4812-4820, 2005
1432005
The trans influence of F, Cl, Br and I ligands in a series of square-planar Pd(II) complexes. Relative affinities of halide anions for the metal centre in trans-[(Ph3P)2Pd(Ph)X]
JP Flemming, MC Pilon, OY Borbulevitch, MY Antipin, VV Grushin
Inorganica Chimica Acta 280 (12), 87-98, 1998
1221998
Structures of MART-126/27–35 Peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition
OY Borbulevych, FK Insaidoo, TK Baxter, DJ Powell Jr, LA Johnson, ...
Journal of molecular biology 372 (5), 1123-1136, 2007
1122007
Lipoxygenase interactions with natural flavonoid, quercetin, reveal a complex with protocatechuic acid in its X‐ray structure at 2.1 Å resolution
OY Borbulevych, J Jankun, SH Selman, E Skrzypczak‐Jankun
Proteins: structure, function, and bioinformatics 54 (1), 13-19, 2004
1072004
Conformational melding permits a conserved binding geometry in TCR recognition of foreign and self molecular mimics
OY Borbulevych, KH Piepenbrink, BM Baker
The Journal of Immunology 186 (5), 2950-2958, 2011
972011
T cell receptor recognition via cooperative conformational plasticity
SJ Gagnon, OY Borbulevych, RL Davis-Harrison, RV Turner, M Damirjian, ...
Journal of molecular biology 363 (1), 228-243, 2006
902006
Disparate degrees of hypervariable loop flexibility control T-cell receptor cross-reactivity, specificity, and binding mechanism
DR Scott, OY Borbulevych, KH Piepenbrink, SA Corcelli, BM Baker
Journal of molecular biology 414 (3), 385-400, 2011
892011
Loss of T cell antigen recognition arising from changes in peptide and major histocompatibility complex protein flexibility: implications for vaccine design
FK Insaidoo, OY Borbulevych, M Hossain, SM Santhanagopolan, ...
Journal of Biological Chemistry 286 (46), 40163-40173, 2011
712011
Accurate macromolecular crystallographic refinement: incorporation of the linear scaling, semiempirical quantum-mechanics program DivCon into the PHENIX refinement package
OY Borbulevych, JA Plumley, RI Martin, KM Merz, LM Westerhoff
Acta Crystallographica Section D: Biological Crystallography 70 (5), 1233-1247, 2014
582014
Unraveling a hotspot for TCR recognition on HLA-A2: evidence against the existence of peptide-independent TCR binding determinants
SJ Gagnon, OY Borbulevych, RL Davis-Harrison, TK Baxter, JR Clemens, ...
Journal of molecular biology 353 (3), 556-573, 2005
502005
Experimental and theoretical study of the structure of N, N-dimethyl-4-nitroaniline derivatives as model compounds for non-linear optical organic materials
OY Borbulevych, RD Clark, A Romero, L Tan, MY Antipin, VN Nesterov, ...
Journal of Molecular Structure 604 (1), 73-86, 2002
502002
Probing dimerization and structural flexibility of mammalian lipoxygenases by small-angle X-ray scattering
W Shang, I Ivanov, DI Svergun, OY Borbulevych, AM Aleem, S Stehling, ...
Journal of molecular biology 409 (4), 654-668, 2011
472011
Fluorine substitutions in an antigenic peptide selectively modulate T-cell receptor binding in a minimally perturbing manner
KH Piepenbrink, OY Borbulevych, RF Sommese, J Clemens, ...
Biochemical Journal 423 (3), 353-361, 2009
422009
Effect of crystal freezing and small-molecule binding on internal cavity size in a large protein: X-ray and docking studies of lipoxygenase at ambient and low temperature at 2 …
E Skrzypczak-Jankun, OY Borbulevych, MI Zavodszky, MR Baranski, ...
Acta Crystallographica Section D: Biological Crystallography 62 (7), 766-775, 2006
422006
Soybean lipoxygenase-3 in complex with 4-nitrocatechol
E Skrzypczak-Jankun, OY Borbulevych, J Jankun
Acta Crystallographica Section D: Biological Crystallography 60 (3), 613-615, 2004
402004
Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A* 0201: implications for WT1-based cancer therapeutics
OY Borbulevych, P Do, BM Baker
Molecular immunology 47 (15), 2519-2524, 2010
372010
Increased peptide contacts govern high affinity binding of a modified TCR whilst maintaining a native pMHC docking mode
DK Cole, M Sami, DR Scott, PJ Rizkallah, OY Borbulevych, PT Todorov, ...
Frontiers in immunology 4, 168, 2013
362013
Lysine Nζ-decarboxylation switch and activation of the β-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus
O Borbulevych, M Kumarasiri, B Wilson, LI Llarrull, M Lee, D Hesek, Q Shi, ...
Journal of Biological Chemistry 286 (36), 31466-31472, 2011
312011
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