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Jae Seung Lee
Jae Seung Lee
Verified email at pennmedicine.upenn.edu
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Year
Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2
M Dittmar, JS Lee, K Whig, E Segrist, M Li, B Kamalia, L Castellana, ...
Cell reports 35 (1), 2021
1682021
Pharmacological activation of STING blocks SARS-CoV-2 infection
M Li, M Ferretti, B Ying, H Descamps, E Lee, M Dittmar, JS Lee, K Whig, ...
Science immunology 6 (59), eabi9007, 2021
1382021
Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2
DC Schultz, RM Johnson, K Ayyanathan, J Miller, K Whig, B Kamalia, ...
Nature 604 (7904), 134-140, 2022
1252022
Drug repurposing screens reveal FDA approved drugs active against SARS-Cov-2
M Dittmar, JS Lee, K Whig, E Segrist, M Li, K Jurado, K Samby, H Ramage, ...
biorxiv, 2020.06. 19.161042, 2020
562020
RACK1 mediates rewiring of intracellular networks induced by hepatitis C virus infection
JS Lee, K Tabata, WI Twu, MS Rahman, HS Kim, JB Yu, MH Jee, ...
PLoS Pathogens 15 (9), e1008021, 2019
422019
New mechanism of hepatic fibrogenesis: hepatitis C virus infection induces transforming growth factor β1 production through glucose-regulated protein 94
MH Jee, KY Hong, JH Park, JS Lee, HS Kim, SH Lee, SK Jang
Journal of Virology 90 (6), 3044-3055, 2016
342016
An mRNA-specific tRNAi carrier eIF2A plays a pivotal role in cell proliferation under stress conditions: stress-resistant translation of c-Src mRNA is mediated by eIF2A
OS Kwon, S An, E Kim, J Yu, KY Hong, JS Lee, SK Jang
Nucleic acids research 45 (1), 296-310, 2017
312017
Femtomolar SARS-CoV-2 antigen detection using the microbubbling digital assay with smartphone readout enables antigen burden quantitation and tracking
H Chen, Z Li, S Feng, M Richard-Greenblatt, E Hutson, S Andrianus, ...
Clinical Chemistry 68 (1), 230-239, 2022
102022
Pyrimidine biosynthesis inhibitors synergize with nucleoside analogs to block SARS-CoV-2 infection
DC Schultz, RM Johnson, K Ayyanathan, J Miller, K Whig, B Kamalia, ...
bioRxiv, 2021.06. 24.449811, 2021
62021
Structure-activity relationships of fluorene compounds inhibiting HCV variants
HS Kim, Y You, J Mun, CG Gadhe, H Moon, JS Lee, AN Pae, M Kohara, ...
Antiviral Research 174, 104678, 2020
22020
SARS-CoV-2 ORF6 protein does not antagonize interferon signaling in respiratory epithelial Calu-3 cells during infection
M Li, K Ayyanathan, M Dittmar, J Miller, I Tapescu, JS Lee, ME McGrath, ...
Mbio 14 (4), e01194-23, 2023
12023
Evolutionary arms race between SARS-CoV-2 and interferon signaling via dynamic interaction with autophagy.
JS Lee, M Dittmar, J Miller, M Li, K Ayyanathan, MB Ferretti, J Hulahan, ...
bioRxiv, 2023.11. 13.566859, 2023
12023
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