Daniel Nichol
Daniel Nichol
Evolutionary Genomics and Modelling, Institute of Cancer Research, UK
Verified email at icr.ac.uk
Cited by
Cited by
Steering evolution with sequential therapy to prevent the emergence of bacterial antibiotic resistance
D Nichol, P Jeavons, AG Fletcher, RA Bonomo, PK Maini, JL Paul, ...
PLoS Comput Biol 11 (9), e1004493, 2015
Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancer
A Dhawan, D Nichol, F Kinose, ME Abazeed, A Marusyk, EB Haura, ...
Scientific Reports 7 (1), 1-9, 2017
Antibiotic collateral sensitivity is contingent on the repeatability of evolution
D Nichol, J Rutter, C Bryant, AM Hujer, S Lek, MD Adams, P Jeavons, ...
Nature communications 10 (1), 1-10, 2019
The 2019 mathematical oncology roadmap
RC Rockne, A Hawkins-Daarud, KR Swanson, JP Sluka, JA Glazier, ...
Physical biology 16 (4), 041005, 2019
Stochasticity in the Genotype-Phenotype Map: Implications for the Robustness and Persistence of Bet-Hedging
D Nichol, M Robertson-Tessi, P Jeavons, ARA Anderson
Genetics 204 (4), 1523-1539, 2016
Evolutionary dynamics of residual disease in human glioblastoma
I Spiteri, G Caravagna, GD Cresswell, A Vatsiou, D Nichol, A Acar, ...
Annals of Oncology 30 (3), 456-463, 2019
The spatiotemporal evolution of lymph node spread in early breast cancer
P Barry, A Vatsiou, I Spiteri, D Nichol, GD Cresswell, A Acar, N Trahearn, ...
Clinical Cancer Research 24 (19), 4763-4770, 2018
Combining radiomics and mathematical modeling to elucidate mechanisms of resistance to immune checkpoint blockade in non-small cell lung cancer
D Saeed-Vafa, R Bravo, JA Dean, A El-Kenawi, NM Père, M Strobl, ...
bioRxiv, 190561, 2017
Exploiting evolutionary herding to control drug resistance in cancer
A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ...
BioRxiv, 566950, 2019
Exploiting evolutionary steering to induce collateral drug sensitivity in cancer
A Acar, D Nichol, J Fernandez-Mateos, GD Cresswell, I Barozzi, SP Hong, ...
Nature Communications 11 (1), 1-14, 2020
Model-based tumor subclonal reconstruction
G Caravagna, T Heide, M Williams, L Zapata, D Nichol, K Chkhaidze, ...
bioRxiv, 586560, 2019
Mapping the breast cancer metastatic cascade onto ctDNA using genetic and epigenetic clonal tracking
GD Cresswell, D Nichol, I Spiteri, H Tari, L Zapata, T Heide, CC Maley, ...
Nature Communications 11 (1), 1-12, 2020
Measuring single cell divisions in human tissues from multi-region sequencing data
B Werner, J Case, MJ Williams, K Chkhaidze, D Temko, ...
Nature Communications 11 (1), 1-9, 2020
Model genotype–phenotype mappings and the algorithmic structure of evolution
D Nichol, M Robertson-Tessi, ARA Anderson, P Jeavons
Journal of the Royal Society Interface 16 (160), 20190332, 2019
A low-cost, open source, self-contained bacterial EVolutionary biorEactor (EVE)
V Gopalakrishnan, NP Krishnan, E McClure, J Pelesko, D Guo, ...
bioRxiv, 729434, 2019
Measuring single cell divisions in human cancers from multi-region sequencing data
B Werner, J Case, MJ Williams, K Chkhaidze, D Temko, ...
bioRxiv, 560243, 2019
It's too soon to pull the plug on antibiotic cycling
D Nichol, RA Bonomo, JG Scott
The Lancet Infectious Diseases 18 (5), 493, 2018
Clonal Evolution of Alternative Splicing in Colorectal Cancer at Single Gland Resolution
J Househam, T Heide, I Spiteri, C Kimberley, D Nichol, E Lakatos, ...
Understanding drug resistance through computational models of the genotype-phenotype mapping
D Nichol
University of Oxford, 2018
Harnessing the lymphocyte meta-phenotype to optimize adoptive cell therapy
A Buttenschoen, A Elkenawi, F El Moustaid, A Fletcher, C Grassberger, ...
bioRxiv, 085910, 2016
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