Alicia Higueruelo
Alicia Higueruelo
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Cited by
Cited by
Structural bioinformatics
J Gu, PE Bourne
John Wiley & Sons, 2009
Arpeggio: a web server for calculating and visualising interatomic interactions in protein structures
HC Jubb, AP Higueruelo, B Ochoa-Montaņo, WR Pitt, DB Ascher, ...
Journal of molecular biology 429 (3), 365-371, 2017
Structural biology and drug discovery for protein–protein interactions
H Jubb, AP Higueruelo, A Winter, TL Blundell
Trends in pharmacological sciences 33 (5), 241-248, 2012
Atomic interactions and profile of small molecules disrupting protein–protein interfaces: the TIMBAL database
AP Higueruelo, A Schreyer, GRJ Bickerton, WR Pitt, CR Groom, ...
Chemical biology & drug design 74 (5), 457-467, 2009
Protein–protein interactions as druggable targets: recent technological advances
AP Higueruelo, H Jubb, TL Blundell
Current opinion in pharmacology 13 (5), 791-796, 2013
Biophysical and computational fragment-based approaches to targeting protein–protein interactions: applications in structure-guided drug discovery
A Winter, AP Higueruelo, M Marsh, A Sigurdardottir, WR Pitt, TL Blundell
Quarterly reviews of biophysics 45 (4), 383-426, 2012
IRAK-4 inhibitors. Part III: a series of imidazo [1, 2-a] pyridines
GM Buckley, R Fosbeary, JL Fraser, L Gowers, AP Higueruelo, LA James, ...
Bioorganic & medicinal chemistry letters 18 (12), 3656-3660, 2008
TIMBAL v2: update of a database holding small molecules modulating protein–protein interactions
AP Higueruelo, H Jubb, TL Blundell
Database 2013, bat039, 2013
IRAK-4 inhibitors. Part II: a structure-based assessment of imidazo [1, 2-a] pyridine binding
GM Buckley, TA Ceska, JL Fraser, L Gowers, CR Groom, AP Higueruelo, ...
Bioorganic & medicinal chemistry letters 18 (11), 3291-3295, 2008
Comprehensive, atomic-level characterization of structurally characterized protein-protein interactions: the PICCOLO database
GR Bickerton, AP Higueruelo, TL Blundell
BMC bioinformatics 12, 1-15, 2011
IRAK-4 inhibitors. Part 1: A series of amides
GM Buckley, L Gowers, AP Higueruelo, K Jenkins, SR Mack, T Morgan, ...
Bioorganic & medicinal chemistry letters 18 (11), 3211-3214, 2008
A DFT computational study of the bis-silylation reaction of acetylene catalyzed by palladium complexes
A Bottoni, AP Higueruelo, GP Miscione
Journal of the American Chemical Society 124 (19), 5506-5513, 2002
What can we learn from the evolution of protein-ligand interactions to aid the design of new therapeutics?
AP Higueruelo, A Schreyer, GRJ Bickerton, TL Blundell, WR Pitt
PLoS One 7 (12), e51742, 2012
Hotspots api: a python package for the detection of small molecule binding hotspots and application to structure-based drug design
PR Curran, CJ Radoux, MD Smilova, RA Sykes, AP Higueruelo, ...
Journal of chemical information and modeling 60 (4), 1911-1916, 2020
Biomolecular forms and functions: a celebration of 50 years of the Ramachandran map
M Gupta
World Scientific, 2013
Protein-protein interactions: structures and druggability
DB Ascher, HC Jubb, DEV Pires, T Ochi, A Higueruelo, TL Blundell
Multifaceted roles of crystallography in modern drug discovery, 141-163, 2015
SInCRe—structural interactome computational resource for Mycobacterium tuberculosis
R Metri, S Hariharaputran, G Ramakrishnan, P Anand, US Raghavender, ...
Database 2015, bav060, 2015
Structural interactomics: informatics approaches to aid the interpretation of genetic variation and the development of novel therapeutics
S Lee, A Brown, WR Pitt, AP Higueruelo, S Gong, GR Bickerton, ...
Molecular Biosystems 5 (12), 1456-1472, 2009
TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species
S Malhotra, G Mugumbate, TL Blundell, AP Higueruelo
Database 2017, bax041, 2017
Fragment-Based Methods for Lead Discovery
NP Pitt, WR Higueruelo, AP Todorov
In silico lead discovery, 83-116, 2010
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