Alicia P Higueruelo
Alicia P Higueruelo
Sosei Heptares
Verified email at soseiheptares.com
TitleCited byYear
Arpeggio: a web server for calculating and visualising interatomic interactions in protein structures
HC Jubb, AP Higueruelo, B Ochoa-Montaņo, WR Pitt, DB Ascher, ...
Journal of molecular biology 429 (3), 365-371, 2017
154*2017
Atomic interactions and profile of small molecules disrupting protein–protein interfaces: the TIMBAL database
AP Higueruelo, A Schreyer, GRJ Bickerton, WR Pitt, CR Groom, ...
Chemical biology & drug design 74 (5), 457-467, 2009
1532009
Structural biology and drug discovery for protein–protein interactions
H Jubb, AP Higueruelo, A Winter, TL Blundell
Trends in pharmacological sciences 33 (5), 241-248, 2012
1522012
Protein–protein interactions as druggable targets: recent technological advances
AP Higueruelo, H Jubb, TL Blundell
Current opinion in pharmacology 13 (5), 791-796, 2013
982013
Biophysical and computational fragment-based approaches to targeting protein–protein interactions: applications in structure-guided drug discovery
A Winter, AP Higueruelo, M Marsh, A Sigurdardottir, WR Pitt, TL Blundell
Quarterly reviews of biophysics 45 (4), 383-426, 2012
812012
IRAK-4 inhibitors. Part III: a series of imidazo [1, 2-a] pyridines
GM Buckley, R Fosbeary, JL Fraser, L Gowers, AP Higueruelo, LA James, ...
Bioorganic & medicinal chemistry letters 18 (12), 3656-3660, 2008
792008
IRAK-4 inhibitors. Part II: a structure-based assessment of imidazo [1, 2-a] pyridine binding
GM Buckley, TA Ceska, JL Fraser, L Gowers, CR Groom, AP Higueruelo, ...
Bioorganic & medicinal chemistry letters 18 (11), 3291-3295, 2008
742008
IRAK-4 inhibitors. Part 1: a series of amides
GM Buckley, L Gowers, AP Higueruelo, K Jenkins, SR Mack, T Morgan, ...
Bioorganic & medicinal chemistry letters 18 (11), 3211-3214, 2008
542008
Comprehensive, atomic-level characterization of structurally characterized protein-protein interactions: the PICCOLO database
GR Bickerton, AP Higueruelo, TL Blundell
BMC bioinformatics 12 (1), 313, 2011
532011
TIMBAL v2: update of a database holding small molecules modulating protein–protein interactions
AP Higueruelo, H Jubb, TL Blundell
Database 2013, 2013
482013
A DFT computational study of the bis-silylation reaction of acetylene catalyzed by palladium complexes
A Bottoni, AP Higueruelo, GP Miscione
Journal of the American Chemical Society 124 (19), 5506-5513, 2002
352002
What can we learn from the evolution of protein-ligand interactions to aid the design of new therapeutics?
AP Higueruelo, A Schreyer, GRJ Bickerton, TL Blundell, WR Pitt
PloS one 7 (12), e51742, 2012
212012
Structural interactomics: informatics approaches to aid the interpretation of genetic variation and the development of novel therapeutics
S Lee, A Brown, WR Pitt, AP Higueruelo, S Gong, GR Bickerton, ...
Molecular Biosystems 5 (12), 1456-1472, 2009
102009
SInCRe—structural interactome computational resource for Mycobacterium tuberculosis
R Metri, S Hariharaputran, G Ramakrishnan, P Anand, US Raghavender, ...
Database 2015, 2015
82015
Protein-protein interactions: structures and druggability
DB Ascher, HC Jubb, DEV Pires, T Ochi, A Higueruelo, TL Blundell
Multifaceted Roles of Crystallography in Modern Drug Discovery, 141-163, 2015
82015
Fragment-Based Methods for Lead Discovery
NP Pitt, WR Higueruelo, AP Todorov
In silico lead discovery, 83-116, 2010
5*2010
TIBLE: a web-based, freely accessible resource for small-molecule binding data for mycobacterial species
S Malhotra, G Mugumbate, TL Blundell, AP Higueruelo
Database 2017, 2017
22017
Multiprotein assemblies: modulating cell activity through targeting protein-protein interfaces
AP HIGUERUELO, H JUBB, TOML BLUNDELL
Biomolecular Forms and Functions: A Celebration of 50 Years of the …, 2013
12013
Molecular recognition from atomic interactions: insights into drug discovery
AP Higueruelo
University of Cambridge, 2012
2012
The Discovery and Characterization of Protein–Protein Interactions
CW Bertoncini, A Higueruelo, X Salvatella
Protein Surface Recognition: Approaches for Drug Discovery, 1-21, 2010
2010
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Articles 1–20