| NASH limits anti-tumour surveillance in immunotherapy-treated HCC D Pfister, NG Núñez, R Pinyol, O Govaere, M Pinter, M Szydlowska, ... Nature 592 (7854), 450-456, 2021 | 768 | 2021 |
| Quiescence modulates stem cell maintenance and regenerative capacity in the aging brain G Kalamakis, D Brüne, S Ravichandran, J Bolz, W Fan, F Ziebell, T Stiehl, ... Cell 176 (6), 1407-1419. e14, 2019 | 312 | 2019 |
| Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming L Solé-Boldo, G Raddatz, S Schütz, JP Mallm, K Rippe, AS Lonsdorf, ... Communications biology 3 (1), 188, 2020 | 283 | 2020 |
| Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH M Dudek, D Pfister, S Donakonda, P Filpe, A Schneider, M Laschinger, ... Nature 592 (7854), 444-449, 2021 | 281 | 2021 |
| DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats D Brocks, CR Schmidt, M Daskalakis, HS Jang, NM Shah, D Li, J Li, ... Nature genetics 49 (7), 1052-1060, 2017 | 270 | 2017 |
| Genome-wide nucleosome positioning during embryonic stem cell development VB Teif, Y Vainshtein, M Caudron-Herger, JP Mallm, C Marth, T Höfer, ... Nature structural & molecular biology 19 (11), 1185-1192, 2012 | 267 | 2012 |
| Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues M Delacher, CD Imbusch, D Weichenhan, A Breiling, A Hotz-Wagenblatt, ... Nature immunology 18 (10), 1160-1172, 2017 | 221 | 2017 |
| HP1 is involved in regulating the global impact of DNA methylation on alternative splicing A Yearim, S Gelfman, R Shayevitch, S Melcer, O Glaich, JP Mallm, ... Cell reports 10 (7), 1122-1134, 2015 | 218 | 2015 |
| Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity M Hick, U Herrmann, SW Weyer, JP Mallm, JA Tschäpe, M Borgers, ... Acta neuropathologica 129, 21-37, 2015 | 202 | 2015 |
| HMGB2 loss upon senescence entry disrupts genomic organization and induces CTCF clustering across cell types A Zirkel, M Nikolic, K Sofiadis, JP Mallm, CA Brackley, H Gothe, ... Molecular cell 70 (4), 730-744. e6, 2018 | 181 | 2018 |
| Precursors for nonlymphoid-tissue Treg cells reside in secondary lymphoid organs and are programmed by the transcription factor BATF M Delacher, CD Imbusch, A Hotz-Wagenblatt, JP Mallm, K Bauer, ... Immunity 52 (2), 295-312. e11, 2020 | 159 | 2020 |
| Nucleosome repositioning links DNA (de) methylation and differential CTCF binding during stem cell development VB Teif, DA Beshnova, Y Vainshtein, C Marth, JP Mallm, T Höfer, K Rippe Genome research 24 (8), 1285-1295, 2014 | 154 | 2014 |
| Suv4-20h2 mediates chromatin compaction and is important for cohesin recruitment to heterochromatin M Hahn, S Dambacher, S Dulev, AY Kuznetsova, S Eck, S Wörz, D Sadic, ... Genes & development 27 (8), 859-872, 2013 | 134 | 2013 |
| Environment‐induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children T Bauer, S Trump, N Ishaque, L Thürmann, L Gu, M Bauer, M Bieg, Z Gu, ... Molecular Systems Biology 12 (3), 861, 2016 | 119 | 2016 |
| Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels T Roider, J Seufert, A Uvarovskii, F Frauhammer, M Bordas, N Abedpour, ... Nature cell biology 22 (7), 896-906, 2020 | 113 | 2020 |
| Haematopoietic stem cells in perisinusoidal niches are protected from ageing M Saçma, J Pospiech, R Bogeska, W de Back, JP Mallm, V Sakk, K Soller, ... Nature cell biology 21 (11), 1309-1320, 2019 | 108 | 2019 |
| Estimating novel potential drug targets of Plasmodium falciparum by analysing the metabolic network of knock-out strains in silico S Fatumo, K Plaimas, JP Mallm, G Schramm, E Adebiyi, M Oswald, R Eils, ... Infection, Genetics and Evolution 9 (3), 351-358, 2009 | 106 | 2009 |
| Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging R Bogeska, AM Mikecin, P Kaschutnig, M Fawaz, M Büchler-Schäff, D Le, ... Cell stem cell 29 (8), 1273-1284. e8, 2022 | 96 | 2022 |
| Specificity, propagation, and memory of pericentric heterochromatin K Müller‐Ott, F Erdel, A Matveeva, JP Mallm, A Rademacher, M Hahn, ... Molecular systems biology 10 (8), 746, 2014 | 95 | 2014 |
| Hypermutation of the inactive X chromosome is a frequent event in cancer N Jäger, M Schlesner, DTW Jones, S Raffel, JP Mallm, KM Junge, ... Cell 155 (3), 567-581, 2013 | 89 | 2013 |
Karsten RippeHead of Division of Chromatin Networks, DKFZ & BioQuantVerified email at dkfz.de
