Metalloregulation of the tumor suppressor protein p53: zinc mediates the renaturation of p53 after exposure to metal chelators in vitro and in intact cells C Méplan, MJ Richard, P Hainaut Oncogene 19 (46), 5227-5236, 2000 | 292 | 2000 |
Two common single nucleotide polymorphisms in the gene encoding β‐carotene 15, 15′‐monoxygenase alter β‐carotene metabolism in female volunteers WC Leung, S Hessel, C Meplan, J Flint, V Oberhauser, F Tourniaire, ... The FASEB Journal 23 (4), 1041-1053, 2009 | 272 | 2009 |
Cadmium induces conformational modifications of wild-type p53 and suppresses p53 response to DNA damage in cultured cells C Méplan, K Mann, P Hainaut Journal of Biological Chemistry 274 (44), 31663-31670, 1999 | 250 | 1999 |
Genetic polymorphisms in the human selenoprotein P gene determine the response of selenoprotein markers to selenium supplementation in a gender‐specific manner (the SELGEN study) C Méplan, LK Crosley, F Nicol, GJ Beckett, AF Howie, KE Hill, G Horgan, ... The FASEB Journal 21 (12), 3063-3074, 2007 | 243 | 2007 |
Selenium status is associated with colorectal cancer risk in the European prospective investigation of cancer and nutrition cohort DJ Hughes, V Fedirko, M Jenab, L Schomburg, C Méplan, H Freisling, ... International journal of cancer 136 (5), 1149-1161, 2015 | 223 | 2015 |
Redox signalling and transition metals in the control of the p53 pathway C Méplan, MJ Richard, P Hainaut Biochemical pharmacology 59 (1), 25-33, 2000 | 212 | 2000 |
Effects of tobacco smoke and benzo[a]pyrene on human endothelial cell and monocyte stress responses M Vayssier-Taussat, T Camilli, Y Aron, C Meplan, P Hainaut, BS Polla, ... American Journal of Physiology-Heart and Circulatory Physiology 280 (3 …, 2001 | 175 | 2001 |
Genetic variants in selenoprotein genes increase risk of colorectal cancer C Méplan, DJ Hughes, B Pardini, A Naccarati, P Soucek, L Vodickova, ... Carcinogenesis 31 (6), 1074-1079, 2010 | 167 | 2010 |
Effects of selenium status and polymorphisms in selenoprotein genes on prostate cancer risk in a prospective study of European men A Steinbrecher, C Méplan, J Hesketh, L Schomburg, T Endermann, ... Cancer epidemiology, biomarkers & prevention 19 (11), 2958-2968, 2010 | 151 | 2010 |
Selenium and viral infection: are there lessons for COVID-19? G Bermano, C Méplan, DK Mercer, JE Hesketh British journal of nutrition 125 (6), 618-627, 2021 | 147 | 2021 |
Four selenoproteins, protein biosynthesis, and Wnt signalling are particularly sensitive to limited selenium intake in mouse colon A Kipp, A Banning, EM van Schothorst, C Meplan, L Schomburg, C Evelo, ... Molecular nutrition & food research 53 (12), 1561-1572, 2009 | 143 | 2009 |
Functional effects of a common single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene: interaction with sex C Méplan, LK Crosley, F Nicol, GW Horgan, JC Mathers, JR Arthur, ... The American journal of clinical nutrition 87 (4), 1019-1027, 2008 | 131 | 2008 |
Supplementation of healthy volunteers with nutritionally relevant amounts of selenium increases the expression of lymphocyte protein biosynthesis genes V Pagmantidis, C Méplan, EM van Schothorst, J Keijer, JE Hesketh The American journal of clinical nutrition 87 (1), 181-189, 2008 | 130 | 2008 |
Relative abundance of selenoprotein P isoforms in human plasma depends on genotype, se intake, and cancer status C Méplan, F Nicol, BT Burtle, LK Crosley, JR Arthur, JC Mathers, ... Antioxidants & redox signaling 11 (11), 2631-2640, 2009 | 126 | 2009 |
Association between maternal micronutrient status, oxidative stress, and common genetic variants in antioxidant enzymes at 15 weeks׳ gestation in nulliparous women who … HD Mistry, CA Gill, LO Kurlak, PT Seed, JE Hesketh, C Méplan, ... Free radical biology and medicine 78, 147-155, 2015 | 96 | 2015 |
Selenium and cancer: a story that should not be forgotten-insights from genomics C Méplan, J Hesketh Advances in Nutrition and Cancer, 145-166, 2014 | 96 | 2014 |
Trace elements and ageing, a genomic perspective using selenium as an example C Méplan Journal of Trace Elements in Medicine and Biology 25, S11-S16, 2011 | 93 | 2011 |
The influence of selenium and selenoprotein gene variants on colorectal cancer risk C Méplan, J Hesketh Mutagenesis 27 (2), 177-186, 2012 | 88 | 2012 |
Selenium and chronic diseases: a nutritional genomics perspective C Méplan Nutrients 7 (5), 3621-3651, 2015 | 87 | 2015 |
Association between polymorphisms in glutathione peroxidase and selenoprotein P genes, glutathione peroxidase activity, HRT use and breast cancer risk C Meplan, LO Dragsted, G Ravn-Haren, A Tjønneland, U Vogel, ... PloS one 8 (9), e73316, 2013 | 84 | 2013 |