Marc Birtwistle
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Raf family kinases: old dogs have learned new tricks
D Matallanas, M Birtwistle, D Romano, A Zebisch, J Rauch, ...
Genes & cancer 2 (3), 232-260, 2011
The library of integrated network-based cellular signatures NIH program: system-level cataloging of human cells response to perturbations
AB Keenan, SL Jenkins, KM Jagodnik, S Koplev, E He, D Torre, Z Wang, ...
Cell systems 6 (1), 13-24, 2018
Cell fate decisions are specified by the dynamic ERK interactome
A Von Kriegsheim, D Baiocchi, M Birtwistle, D Sumpton, W Bienvenut, ...
Nature cell biology 11 (12), 1458-1464, 2009
Critical role of histone turnover in neuronal transcription and plasticity
I Maze, W Wenderski, KM Noh, RC Bagot, N Tzavaras, I Purushothaman, ...
Neuron 87 (1), 77-94, 2015
Ligand‐dependent responses of the ErbB signaling network: experimental and modeling analyses
MR Birtwistle, M Hatakeyama, N Yumoto, BA Ogunnaike, JB Hoek, ...
Molecular systems biology 3 (1), 144, 2007
The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier
OE Sturm, R Orton, J Grindlay, M Birtwistle, V Vyshemirsky, D Gilbert, ...
Science signaling 3 (153), ra90-ra90, 2010
Ligand-specific c-Fos expression emerges from the spatiotemporal control of ErbB network dynamics
T Nakakuki, MR Birtwistle, Y Saeki, N Yumoto, K Ide, T Nagashima, ...
Cell 141 (5), 884-896, 2010
Evaluating strategies to normalise biological replicates of Western blot data
A Degasperi, MR Birtwistle, N Volinsky, J Rauch, W Kolch, ...
PloS one 9 (1), e87293, 2014
Bistability in the Rac1, PAK, and RhoA signaling network drives actin cytoskeleton dynamics and cell motility switches
KM Byrne, N Monsefi, JC Dawson, A Degasperi, JC Bukowski-Wills, ...
Cell systems 2 (1), 38-48, 2016
A multi-center study on the reproducibility of drug-response assays in mammalian cell lines
M Niepel, M Hafner, CE Mills, K Subramanian, EH Williams, M Chung, ...
Cell systems 9 (1), 35-48. e5, 2019
Novel somatic mutations to PI3K pathway genes in metastatic melanoma
AY Shull, A Latham-Schwark, P Ramasamy, K Leskoske, D Oroian, ...
Public Library of Science 7 (8), e43369, 2012
Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise
MR Birtwistle, J Rauch, A Kiyatkin, E Aksamitiene, M Dobrzyński, JB Hoek, ...
BMC systems biology 6, 1-12, 2012
NFκB and HIF display synergistic behaviour during hypoxic inflammation
U Bruning, SF Fitzpatrick, T Frank, M Birtwistle, CT Taylor, A Cheong
Cellular and Molecular Life Sciences 69, 1319-1329, 2012
Four‐dimensional dynamics of MAPK information‐processing systems
BN Kholodenko, MR Birtwistle
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 1 (1), 28-44, 2009
ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2
A von Thun, M Birtwistle, G Kalna, J Grindlay, D Strachan, W Kolch, ...
Journal of cell science 125 (6), 1465-1477, 2012
Drug response consistency in CCLE and CGP
M Bouhaddou, MS DiStefano, EA Riesel, E Carrasco, HY Holzapfel, ...
Nature 540 (7631), E9-E10, 2016
Cell size assays for mass cytometry
AD Stern, AH Rahman, MR Birtwistle
Cytometry Part A 91 (1), 14-24, 2017
A comparison of mRNA sequencing with random primed and 3′-directed libraries
Y Xiong, M Soumillon, J Wu, J Hansen, B Hu, JG Van Hasselt, ...
Scientific reports 7 (1), 14626, 2017
A mechanistic pan-cancer pathway model informed by multi-omics data interprets stochastic cell fate responses to drugs and mitogens
M Bouhaddou, AM Barrette, AD Stern, RJ Koch, MS DiStefano, EA Riesel, ...
PLoS computational biology 14 (3), e1005985, 2018
Endocytosis and signalling: a meeting with mathematics
MR Birtwistle, BN Kholodenko
Molecular oncology 3 (4), 308-320, 2009
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