| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2161 | 2019 |
| Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ... Nature genetics 43 (5), 436-441, 2011 | 2133 | 2011 |
| Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline K Talbot, HY Wang, H Kazi, LY Han, KP Bakshi, A Stucky, RL Fuino, ... The Journal of clinical investigation 122 (4), 1316-1338, 2012 | 1817 | 2012 |
| The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease SE Arnold, BT Hyman, J Flory, AR Damasio, GW Van Hoesen Cerebral cortex 1 (1), 103-116, 1991 | 1760 | 1991 |
| Loneliness and risk of Alzheimer disease RS Wilson, KR Krueger, SE Arnold, JA Schneider, JF Kelly, LL Barnes, ... Archives of general psychiatry 64 (2), 234-240, 2007 | 1743 | 2007 |
| Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis WJ Jansen, R Ossenkoppele, DL Knol, BM Tijms, P Scheltens, ... Jama 313 (19), 1924-1938, 2015 | 1482 | 2015 |
| Primary age-related tauopathy (PART): a common pathology associated with human aging JF Crary, JQ Trojanowski, JA Schneider, JF Abisambra, EL Abner, ... Acta neuropathologica 128, 755-766, 2014 | 1312 | 2014 |
| Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums SE Arnold, Z Arvanitakis, SL Macauley-Rambach, AM Koenig, HY Wang, ... Nature Reviews Neurology 14 (3), 168-181, 2018 | 1128 | 2018 |
| Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis Y Iturria-Medina, RC Sotero, PJ Toussaint, JM Mateos-Pérez, AC Evans Nature communications 7 (1), 11934, 2016 | 988 | 2016 |
| An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers TR Bomfim, L Forny-Germano, LB Sathler, J Brito-Moreira, JC Houzel, ... The Journal of clinical investigation 122 (4), 1339-1353, 2012 | 908 | 2012 |
| Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 896 | 2017 |
| The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study DA Bennett, JA Schneider, Y Tang, SE Arnold, RS Wilson The Lancet Neurology 5 (5), 406-412, 2006 | 895 | 2006 |
| Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer’s Coordinating Centre JB Toledo, SE Arnold, K Raible, J Brettschneider, SX Xie, M Grossman, ... Brain 136 (9), 2697-2706, 2013 | 786 | 2013 |
| Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson’s disease HI Hurtig, JQ Trojanowski, J Galvin, D Ewbank, ML Schmidt, VMY Lee, ... Neurology 54 (10), 1916-1921, 2000 | 722 | 2000 |
| Education modifies the relation of AD pathology to level of cognitive function in older persons DA Bennett, RS Wilson, JA Schneider, DA Evans, CF Mendes de Leon, ... Neurology 60 (12), 1909-1915, 2003 | 703 | 2003 |
| Altered neuregulin 1–erbB4 signaling contributes to NMDA> receptor hypofunction in schizophrenia CG Hahn, HY Wang, DS Cho, K Talbot, RE Gur, WH Berrettini, K Bakshi, ... Nature medicine 12 (7), 824-828, 2006 | 688 | 2006 |
| FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease NL Foster, JL Heidebrink, CM Clark, WJ Jagust, SE Arnold, NR Barbas, ... Brain 130 (10), 2616-2635, 2007 | 686 | 2007 |
| Depressive symptoms, cognitive decline, and risk of AD in older persons RS Wilson, LL Barnes, CF Mendes de Leon, NT Aggarwal, JS Schneider, ... Neurology 59 (3), 364-370, 2002 | 664 | 2002 |
| Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy GU Höglinger, NM Melhem, DW Dickson, PMA Sleiman, LS Wang, L Klei, ... Nature genetics 43 (7), 699-705, 2011 | 615 | 2011 |
| Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions VM Van Deerlin, PMA Sleiman, M Martinez-Lage, A Chen-Plotkin, ... Nature genetics 42 (3), 234-239, 2010 | 589 | 2010 |
