Alexander K Buell
Alexander K Buell
Professor of Protein Biophysics, Technical University of Denmark, DTU
Verified email at dtu.dk
TitleCited byYear
Nanostructured films from hierarchical self-assembly of amyloidogenic proteins
TPJ Knowles, TW Oppenheim, AK Buell, DY Chirgadze, ME Welland
Nature nanotechnology 5 (3), 204, 2010
2742010
Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation
AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, ...
Proceedings of the National Academy of Sciences 111 (21), 7671-7676, 2014
2732014
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, ...
Nature chemical biology 11 (3), 229, 2015
2452015
The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation
N Lorenzen, SB Nielsen, AK Buell, JD Kaspersen, P Arosio, BS Vad, ...
Journal of the American Chemical Society 136 (10), 3859-3868, 2014
1392014
Protein aggregation in crowded environments
DA White, AK Buell, TPJ Knowles, ME Welland, CM Dobson
Journal of the American Chemical Society 132 (14), 5170-5175, 2010
1192010
Binding of the Molecular Chaperone alpha B-Crystallin to A beta Amyloid Fibrils Inhibits Fibril Elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ...
Biophysical journal 101 (7), 1681-1689, 2011
1172011
Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy
D Pinotsi, AK Buell, C Galvagnion, CM Dobson, GS Kaminski Schierle, ...
Nano letters 14 (1), 339-345, 2013
1142013
Ostwald’s rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers
A Levin, TO Mason, L Adler-Abramovich, AK Buell, G Meisl, C Galvagnion, ...
Nature communications 5, 5219, 2014
942014
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson’s disease
G Tóth, SJ Gardai, W Zago, CW Bertoncini, N Cremades, SL Roy, ...
PLoS One 9 (2), e87133, 2014
892014
Expanding the solvent chemical space for self-assembly of dipeptide nanostructures
TO Mason, DY Chirgadze, A Levin, L Adler-Abramovich, E Gazit, ...
ACS nano 8 (2), 1243-1253, 2014
892014
A label‐free, quantitative assay of amyloid fibril growth based on intrinsic fluorescence
D Pinotsi, AK Buell, CM Dobson, GS Kaminski Schierle, CF Kaminski
ChemBioChem 14 (7), 846-850, 2013
882013
Detailed analysis of the energy barriers for amyloid fibril growth
AK Buell, A Dhulesia, DA White, TPJ Knowles, CM Dobson, ME Welland
Angewandte Chemie International Edition 51 (21), 5247-5251, 2012
842012
Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
C Galvagnion, JWP Brown, MM Ouberai, P Flagmeier, M Vendruscolo, ...
Proceedings of the National Academy of Sciences 113 (26), 7065-7070, 2016
802016
Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation
P Flagmeier, G Meisl, M Vendruscolo, TPJ Knowles, CM Dobson, ...
Proceedings of the National Academy of Sciences 113 (37), 10328-10333, 2016
722016
Protein microgels from amyloid fibril networks
U Shimanovich, I Efimov, TO Mason, P Flagmeier, AK Buell, A Gedanken, ...
ACS nano 9 (1), 43-51, 2015
702015
Electrostatic effects in filamentous protein aggregation
AK Buell, P Hung, X Salvatella, ME Welland, CM Dobson, TPJ Knowles
Biophysical journal 104 (5), 1116-1126, 2013
702013
Population of nonnative states of lysozyme variants drives amyloid fibril formation
AK Buell, A Dhulesia, MF Mossuto, N Cremades, JR Kumita, M Dumoulin, ...
Journal of the American Chemical Society 133 (20), 7737-7743, 2011
662011
Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages
T Guilliams, F El-Turk, AK Buell, EM O'Day, FA Aprile, EK Esbjörner, ...
Journal of molecular biology 425 (14), 2397-2411, 2013
592013
Frequency factors in a landscape model of filamentous protein aggregation
AK Buell, JR Blundell, CM Dobson, ME Welland, EM Terentjev, ...
Physical review letters 104 (22), 228101, 2010
562010
Interactions between amyloidophilic dyes and their relevance to studies of amyloid inhibitors
AK Buell, CM Dobson, TPJ Knowles, ME Welland
Biophysical journal 99 (10), 3492-3497, 2010
522010
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Articles 1–20