Alexander K Buell
Alexander K Buell
Professor of Protein Biophysics, Technical University of Denmark, DTU
Verified email at
Cited by
Cited by
Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation
AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, ...
Proceedings of the National Academy of Sciences 111 (21), 7671-7676, 2014
Nanostructured films from hierarchical self-assembly of amyloidogenic proteins
TPJ Knowles, TW Oppenheim, AK Buell, DY Chirgadze, ME Welland
Nature nanotechnology 5 (3), 204, 2010
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, ...
Nature chemical biology 11 (3), 229, 2015
The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation
N Lorenzen, SB Nielsen, AK Buell, JD Kaspersen, P Arosio, BS Vad, ...
Journal of the American Chemical Society 136 (10), 3859-3868, 2014
Binding of the Molecular Chaperone alpha B-Crystallin to A beta Amyloid Fibrils Inhibits Fibril Elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ...
Biophysical journal 101 (7), 1681-1689, 2011
Direct observation of heterogeneous amyloid fibril growth kinetics via two-color super-resolution microscopy
D Pinotsi, AK Buell, C Galvagnion, CM Dobson, GS Kaminski Schierle, ...
Nano letters 14 (1), 339-345, 2014
Protein aggregation in crowded environments
DA White, AK Buell, TPJ Knowles, ME Welland, CM Dobson
Journal of the American Chemical Society 132 (14), 5170-5175, 2010
Ostwald’s rule of stages governs structural transitions and morphology of dipeptide supramolecular polymers
A Levin, TO Mason, L Adler-Abramovich, AK Buell, G Meisl, C Galvagnion, ...
Nature communications 5 (1), 1-8, 2014
Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein
C Galvagnion, JWP Brown, MM Ouberai, P Flagmeier, M Vendruscolo, ...
Proceedings of the National Academy of Sciences 113 (26), 7065-7070, 2016
Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation
P Flagmeier, G Meisl, M Vendruscolo, TPJ Knowles, CM Dobson, ...
Proceedings of the National Academy of Sciences 113 (37), 10328-10333, 2016
Expanding the solvent chemical space for self-assembly of dipeptide nanostructures
TO Mason, DY Chirgadze, A Levin, L Adler-Abramovich, E Gazit, ...
ACS nano 8 (2), 1243-1253, 2014
Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson’s disease
G Toth, SJ Gardai, W Zago, CW Bertoncini, N Cremades, SL Roy, ...
PloS one 9 (2), 2014
A label‐free, quantitative assay of amyloid fibril growth based on intrinsic fluorescence
D Pinotsi, AK Buell, CM Dobson, GS Kaminski Schierle, CF Kaminski
ChemBioChem 14 (7), 846-850, 2013
Detailed analysis of the energy barriers for amyloid fibril growth
AK Buell, A Dhulesia, DA White, TPJ Knowles, CM Dobson, ME Welland
Angewandte Chemie International Edition 51 (21), 5247-5251, 2012
Protein microgels from amyloid fibril networks
U Shimanovich, I Efimov, TO Mason, P Flagmeier, AK Buell, A Gedanken, ...
ACS nano 9 (1), 43-51, 2015
Electrostatic effects in filamentous protein aggregation
AK Buell, P Hung, X Salvatella, ME Welland, CM Dobson, TPJ Knowles
Biophysical journal 104 (5), 1116-1126, 2013
Population of nonnative states of lysozyme variants drives amyloid fibril formation
AK Buell, A Dhulesia, MF Mossuto, N Cremades, JR Kumita, M Dumoulin, ...
Journal of the American Chemical Society 133 (20), 7737-7743, 2011
Nanobodies raised against monomeric α-synuclein distinguish between fibrils at different maturation stages
T Guilliams, F El-Turk, AK Buell, EM O'Day, FA Aprile, EK Esbj÷rner, ...
Journal of molecular biology 425 (14), 2397-2411, 2013
Secondary nucleation of monomers on fibril surface dominates α-synuclein aggregation and provides autocatalytic amyloid amplification
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, ...
Quarterly reviews of biophysics 50, 2017
Frequency factors in a landscape model of filamentous protein aggregation
AK Buell, JR Blundell, CM Dobson, ME Welland, EM Terentjev, ...
Physical review letters 104 (22), 228101, 2010
The system can't perform the operation now. Try again later.
Articles 1–20